To characterize the gene networks underlying the
fusion of myoblasts into muscle fibers during embryonic development and muscle repair.
«We were able to identify the receptor BAI3, a protein at the
surface of myoblasts, as one of the crucial missing links in the fusion of muscle cells,» adds Dr. Côté.
During the developmental phase, cells are formed by the
combination of myoblasts, which are undifferentiated, mononucleated cells.
Other potential treatments after careful consideration of side - effects and that are recommended under the supervision of a cardiologist include medications such as carvedilol and metoprolol or
injections of myoblasts (viable cells) into the myocardium (heart muscle).
The
fusion of myoblasts is a critical step in the formation of embryonic muscle fibers as it determines muscle size, among other things.