This permits chronic and excessive oxidation
of the myofibers and disruption of the proper oxidant - antioxidant balance.»
Not exact matches
«They end up with many dysfunctional mitochondria, which compromise repair
of injured
myofibers.
Although reactive oxygen species can damage cells when produced in high amounts, according to a study published online Sept. 5, 2017 by Science Signaling and featured on the journal's cover, these oxidative species are crucial signals that start the process
of repairing
myofiber.
Mitochondria help injured muscle cells (
myofibers) repair by soaking up calcium that enters from the site
of injury and using it to trigger increased production
of reactive oxygen species.
We investigated the role
of Srf in two cellular compartments
of mouse skeletal muscle (
myofibers and adult muscle stem cells) upon different perturbation
of muscle homeostasis (hypertrophy, atrophy, regeneration).
Abstract During muscle regeneration, the conversion
of muscle stem cells to terminally differentiated
myofibers requires multiple cell fate transitions.
In the present seminar, I will summarize our findings concerning the role
of Srf in
myofibers to control muscle mass and I will present recent data identifying Srf as a master regulator
of muscle stem cell fusion and demonstrating the implication
of F - actin architecture in this process.
Effect
of the different experimental conditions on the glycogen, intracellular glucose, and G6P content in cultures
of human
myofibers.
Effect
of preculturing human satellite cell cultures in increasing concentrations
of insulin on the basal and insulin - stimulated glucose transport activity in cultures
of human
myofibers.
Note elongated median nuclei and the two parallel strands
of striated
myofibers.
(I) Closeup
of (F)(orange square) showing cross-sectioned
myofibers (red arrow).
Efficacy
of 3 days / wk resistance training on
myofiber hypertrophy and myogenic mechanisms in young vs. older adults