However, Setd7 expression increased with the progression
of myogenesis in vitro indicating the potential importance of this event for skeletal muscle development and regeneration in vivo.
Preliminary data we have now obtained further indicate that in somite cells, the activation of the NOTCH pathway triggers a «signalling module» that couples the initiation
of myogenesis with the epithelial - mesenchymal transition (EMT) that allows them to migrate into the growing muscle.
Not exact matches
«For several years, we have been studying
myogenesis, a process by which muscles are formed during embryonic development,» says Jean - François Côté, PhD, Director
of the Cytoskeletal Organization and Cell Migration research unit at the IRCM.
To assess the role
of hlh - 1 in C. elegans
myogenesis, genetic deficiencies spanning the hlh - 1 locus were isolated after gamma irradiation.
In the course
of this process, signals from the microenvironment instruct cycling MuSCs and control
myogenesis.
Accordingly, our data suggests that the failure
of regenerative
myogenesis to keep pace with disease progression in DMD is not due to muscle stem cell exhaustion, but rather is due to a cell - autonomous deficiency in asymmetric division.
Moreover, we showed that via the production
of Oncostatin - M, restorative macrophages promoted
myogenesis / angiogenesis coupling.
Title: Muscle satellite cells are primed for
myogenesis, but maintain quiescence with sequestration
of Myf5 mRNA targeted by microRNA - 31 in mRNP granules Authors: Crist CG, Montarras D, Buckingham M Date: 2012 Publication Details: Cell Stem Cell 2012 Jul 6:11 (1): 118 - 126
Altenburger, A. Wanninger, Comparative larval
myogenesis and adult myoanatomy
of the rhynchonelliform (articulate) brachiopods Argyrotheca cordata, A. cistellula, and Terebratalia transversa.