Sentences with phrase «of myosin»

To determine whether FLRG can also inhibit myostatin activity in vivo, I generated a construct in which the FLRG coding sequence was placed downstream of a myosin light chain promoter / enhancer.

We investigated the role of myosin VI by examining the retinas of mice carrying a null mutation in the myosin VI gene.

They discovered that a form of myosin, alpha - myosin, triggers the development of autoimmunity after a heart attack.

«His extensive knowledge base of myosin motors and his enthusiasm for this application of it made him a natural partner in the project.

Hickson, et al., Glutamine prevents down regulation of myosin heavy chain synthesis and muscle atrophy from glucocorticoids, Am J Physiol, 1995, 268: E730 - E734.

A phylogenetic analysis of myosin heavy chain type II sequences corroborates that Acoela and Nemertodermatida are basal bilaterians.

A dehydrated body, with an increased concentration of myosin in its sludgy blood, is hard enough on the kidneys; add multiple doses of NSAID pain - relievers (like ibuprofen), which shrink the kidneys, and you have a perfect storm for renal failure.

Christine Petit, a molecular biologist at the Pasteur Institute in Paris, found that all 22 deaf individuals in a large family in southern Tunisia carry double copies of the myosin mutation.

In this way, we have measured the strength of the myosin pull under tension.

Steven Lade, a Ph.D. student at the Australian National University in Canberra, does the dance of myosin - V, a molecular motor that moves vesicles around inside cells by migrating along actin fibers.

Interestingly, Myh9 is also mutated in human head and neck cancers, and low expression of myosin IIa correlates with poor prognosis for the patient,» says Fuchs.

Plant genomes encode the myosin XI family of myosin proteins.

Capitanio M., Canepari M., Maffei M., Beneventi D., Monico C., Vanzi F., Bottinelli R., and F. S. Pavone, Ultrafast force - clamp spectroscopy of single molecules reveals load dependence of myosin working stroke, Nature Methods 9, 1013 - 1019 (2012).

Its structure was reminiscent of myosin, a motor protein.

The work by the Houdusse team and Cytokinetics highlights how specific modulators of myosin activity have great potential to provide new treatments against human diseases.

«There are millions of myosin molecules in a muscle fiber and each one individually generates a displacement,» said Christopher M. Yengo, associate professor of cellular and molecular physiology.

Scientists are interested in the timing of the movement of myosin along actin filaments which is driven by the power stroke — a process called lever arm swing.

They attached fluorescent probes to parts of the myosin motor and observed distance changes between the glowing probe sites to time the protein's force - generating movements.

Thus, the deficiency of vitamin E decreased the amount of myosin, glycogen, potassium, magnesium, phosphorus and creatine in muscle.

Additionally, they are all dependent upon the assumption that limiting factor for the speed at which cross-bridge cycling can occur is the speed at which the ATPase of the myosin head can hydrolyze ATP to power the process.

a protein complex in muscle fibers; composed of myosin and actin; shortens when stimulated and causes muscle contractions

He also zeroed in on the mechanics of the myosin power stroke (the myosin head) as a better place to address the problems of a failing hearts.

The research topic was determining the role of myosin in wound - induced polyploidization