Sentences with phrase «of myotubes»
Along those lines, it was also recently shown that ROS function as important signaling molecules for muscle hypertrophy in vitro, where it was found that IGF - 1 induced hypertrophy of myotubes in culture is suppressed by antioxidants (15).
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Within days, the neural stem cells began to make proteins typical of muscle cells, and even joined with the muscle cells to form myotubes, tubes of fused cells that make up the bulk of living muscle.
In vitro experiments in myogenic cells initially suggested that IL - 15 was an anabolic factor for skeletal muscle, able to stimulate the accumulation of contractile protein in differentiated myotubes (8 — 10).
Post-transcriptional regulation of autophagy in C2C12 myotubes following starvation and nutrient restoration.
However, further investigations are needed to clarify whether previous metabolic influences at the level of quiescent satellite cells in vivo can induce irreversible metabolic changes in cultured human myotubes.
In this context, cultures of primary human myotubes offer excellent material for performing studies under standardized conditions.
Our dose - response curve at chronic high insulin levels allowed us to differentiate between a primary defect (probably genetic) and the induction of secondary insulin resistance in myotube cultures due to hyperinsulinemia.
Our «biased» profiling is based on an in vitro model of mouse terminally differentiated myotubes, induced to re-enter the cell cycle by the E1A oncogene (23).
Overexpression of FOXO3A in mouse myotubes also significantly up - regulates MAFbx expression (49).
Amino acids and insulin act additively to regulate components of the ubiquitin - proteasome pathway in C2C12 myotubes