But the
cells of naked mole rats behave as if they are «claustrophobic», ceasing to divide much sooner than cells from other species.
When they compared the amino acid
sequence of naked mole rat protein, the researchers found that three of these protein building blocks were different from the rat version and one was also different from the same protein in other mole rats.
Claustrophobic cells Three years ago, Gorbunova was involved in another study that described the unusual way in which the cells
of the naked mole rat behave in the lab.
They found that a dilute
solution of naked mole rat skin cells did start to proliferate, but stopped once the cells reached a certain, relatively low density.
The study was the first to analyze the life histories of
thousands of naked mole rats, and found that their risk of death doesn't go up as they grow older, as it does for every other known mammalian species.
To fake a photo of an ice borer that accompanied the hoax story, the magazine's art department Photoshopped a red - tinted trilobite onto the
head of a naked mole rat.
They reported that a factor in the cells
of naked mole rats protects and alters the activity of the proteasome, a garbage disposer for damaged and obsolete proteins.
IN A small room in the lab - animal wing of the University of Illinois at Chicago, biologist Thomas Park peers into a plastic box
full of naked mole rats.
Whether it's the discovery of the unique cancer - fighting
gene of the naked mole rat or the creation of a mouse model of melanoma, we see progress as, well, progress.
The
lifespan of naked mole rats is 10 - 30 years, while its cousins - rat and mice - can live only up to 4 years, and are very prone to tumors.
Last week, a research consortium posted the draft
sequence of the naked mole rat's genome online; further study may unlock the genetic clues to this unique animal's survival abilities.
«We thought the blind - mole - rat cells would use the same mechanism as
those of naked mole rats,» says Gorbunova, «so the fact that they do not was a big surprise».