Sentences with phrase «of nanomedicines»

«The main focus now is to search for techniques allowing for increased accumulation of nanomedicines in the tumor which should potentially allow for higher efficacy and in parallel thinking about more sophisticated constructs which are capable of interacting with the tumor microenvironment,» he said.

«In order to increase therapeutic effectiveness, it is critical to find general principles that can positively influence uptake of nanomedicines into cells,» says Shastri.

«Despite huge efforts in the field of nanomedicine, fewer nanoparticle technologies than expected have made it to clinical trials.

Further work needs to be done, too, in determining how best to deliver the treatment and in other areas, such as modifying the size and surface chemistry of the nanomedicine so that the body can accommodate it safely.

«Probably the neatest thing about this is that so much of nanomedicine has been about exploiting the magnetic and optical properties of nanomaterials, and we have great examples of that at Rice,» Colvin said.

«We demonstrated that the co-administration of the iRGD peptide with the particles can enhance the effectiveness of pancreatic cancer treatment in the tumor model, leading to increased tumor shrinkage, disappearance of metastases and enhanced animal survival» said Meng, an adjunct assistant professor of nanomedicine.

Professor Knight added: «Super resolution microscopy is a major step forward and we are looking forward to using this technology in a wide range of applications from stem cell behaviour to understanding arthritis or the development of nanomedicine.»

The study, by Marvin and Ann Dilley White Chair and Distinguished Professor Dr. Tadeusz Malinski and two graduate students, Alamzeb Khan and Hazem Dawoud, has been published in the International Journal of Nanomedicine.

Professor Subbu Venkatraman, Chair of NTU's School of Materials Science and Engineering and Prof Wong's research partner, said the successful study of liposomal latanoprost can be hailed one of Singapore's early successes in the emerging area of nanomedicine.

The manipulation and analysis of biological objects will open a new door to early disease diagnosis and the discovery of nanomedicine.»

Ferrari, considered one of the founders of nanomedicine and transport oncophysics (the physics of mass transport within a cancer lesion), says researchers and clinicians need to understand the limitations of transport mechanisms to identify effective immunotherapy treatments for patients.

International journal of nanomedicine, 8.

Inhaled chemotherapy in lung cancer: future concept of nanomedicine.

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

Nanotheranostics publishes innovative and original basic, translational and clinical research reflecting the fields of nanomedicine, nanoimaging, drug and gene delivery, nanoelectronic biosensors, and other areas.

In the field of nanomedicine, CEA - Léti has developed, over the past 9 years, a growing expertise in molecular optical imaging based on fluorescence imaging, and on nanocarriers for drug delivery.

The first volume of the Nanomedicine book series describes the set of basic capabilities of molecular machine systems that may be required by many, if not most, medical nanorobotic devices, including the physical, chemical, thermodynamic, mechanical, and biological limits of such devices.

«Such long term, collaborative interactions are paying off, leading to the gelling of the nanomedicine community.»

We hope that this special issue may help to bring the different actors of nanomedicine closer together and encourage scientists to better understand other actors which act outside their own comfort zone.

He is also in the Advisory Board of Nanomedicine, Nanotechnology Reviews and the Journal of Peptide Science.

Each issue of Nanomedicine: NBM presents theoretical and experimental research results related to nanoscience and nanotechnology in life sciences, including Basic, Translational, and Clinical research, and commercialization of results.

Not exact matches

Maastricht, The Netherlands, 1 November 2017 — Cristal Therapeutics, a clinical stage biopharmaceutical company developing targeted nanomedicines for the treatment of cancer and other diseases with high unmet patient need, announced today that it has begun a Phase 1b...

In his first few years as a principal investigator (PI), working with stem cells and emerging nanotechnologies to develop nanomedicines, Ferreira was able to make do by licensing some of his technologies and securing industry funding and Portuguese government grants.

Xiaoyuan Chen, Ph.D., Chief of the Laboratory of Molecular Imaging and Nanomedicine at NIBIB, and his team attempted to solve this problem by developing a radiotracer that could identify prostate cancer at all stages.

said co-corresponding author Morteza Mahmoudi, PhD, an instructor in the Center for Nanomedicine and Department of Anesthesiology at BWH.

«The siRNA delivery targeted carriers constructed today hone in on specific cells and require chemical conjugation of the targeting agent,» says Prof. Dan Peer of the Laboratory of Precision Nanomedicine at TAU's School of Molecular Cell Biology and Biotechnology, who led the research.

For this study, Tomasson collaborated with nanomedicine expert Gregory M. Lanza, MD, PhD, the Oliver M. Langenberg Distinguished Professor of Science and Practice of Medicine, whose lab synthesized and modified a compound discovered by Edward V. Prochownik, MD, PhD, of the University of Pittsburgh.

The country's 2006 — 2010 Science & Technology Plan identified nanotechnology and new materials as part of eight promotion areas and helped establish a new section of Japan's National Institute of Health Sciences (NIHS) that focuses on nanomedicine.

They'll also work with materials scientists to create a reproduction that mirrors the composition of different - shaped nanoparticles to see how they navigate through the bloodstream so the team can run virtual tests of new treatments in nanomedicine.

Singapore has shown to be a powerhouse of nanotech research as «it is pouring lots of money into recruiting high - level scientists in nanomedicine and nanotechnology,» says Scott McNeil, who heads the U.S. National Cancer Institute's Nanotechnology Characterization Laboratory (NCL).

In late 2009, the Lundbeck Foundation announced a grant of $ 6 million to establish the Lundbeck Foundation Nanomedicine Centre for Individualised Management of Tissue Damage and Regeneration, at Aarhus University.

Shieh is currently leading the International Institute of Macromolecular Analysis and Nanomedicine Innovation (IMANI), which is focused on translating molecular discoveries to the clinic.

Lal serves as co-director for the Center of Excellence for Nanomedicine and Engineering, a subcenter of the Institute of Engineering in Medicine at UC San Diego.

«This technology has the potential to profoundly change the way breast cancer in particular and cancers in general are both studied and treated,» said Chad A. Mirkin, a nanomedicine expert and a corresponding author of the study.

Published in Nanomedicine, the study identified a new mechanism of targeting multi-subunit complexes that are critical to the function of viruses, bacteria or cancer, thus reducing or possibly even eliminating their resistance to targeted drugs.

In their report that has received advance online publication in Nature Nanotechnology, a research team based at the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) describes how a nanomedicine that combines photodynamic therapy — the use of light to trigger a chemical reaction — with a molecular therapy drug targeted against common treatment resistance pathways reduced a thousand-fold the dosage of the molecular therapy drug required to suppress tumor progression and metastatic outgrowth in an animal model.

A combination of iron - oxide nanoparticles and an alternating magnetic field, which together generate heat, have activated an immune system response to tumors in mice according to an accepted manuscript by Dartmouth - Hitchcock Norris Cotton Center researchers in the journal Nanomedicine: Nanotechnology, Biology and Medicine released online on February 24, 2014.

She became a member of the Center for Drug Delivery and Nanomedicine (CDDN) and director of the CNS Drug Delivery Program at CDDN in 2004.

«We think that the problem begins much earlier, with the in vitro tests that are performed at the starting point of translational nanomedicine: their static design is what often accounts for the discrepancies with the later in vivo tests.»

«Surprisingly, the influence of lymph on the protein corona and the fate of nanoparticles has so far been completely neglected — although subcutaneously injected nanomedicines immediately contact the patient's lymph,» says Mioni?

The work was funded by a nine - year grant from the National Institutes of Health for the Nanomedicine Development Center for the Optical Control of Biological Function (PN2EY018241), as well a NIH grants RO1EY06855 and P30EY001583, and by a grant from the Foundation Fighting Blindness, USA.

The tough challenges we faced were to make this nanocapsule stable and biocompatible, while at the same time controlling the release of the drug at the desired rate over months,» added Prof Venkatraman, the founding director of the NTU - Northwestern Institute for Nanomedicine.

The new nanomedicine is delivered to the front of the eye via a painless injection and will stay and release the anti-glaucoma drugs slowly over the next six months.

Co-lead scientist Associate Professor Tina Wong, who is the head of the Ocular Therapeutics and Drug Delivery Research Group at the Singapore Eye Research Institute, said the new nanomedicine will benefit the elderly, as they often forget to use the daily eye drops, leading to the worsening of their conditions.

«Although treatable at the early stage, prostate cancer is prone to metastasis,» explain the team of authors, led by Xiaoyuan Chen, senior investigator, Laboratory of Molecular Imaging and Nanomedicine at the U.S. National Institute of Biomedical Imaging and Bioengineering.

The nanomedicine platform consists of silicon naphthalocyanine (SiNc) densely packed in biodegradable PEG - PCL nanoparticles.

Asst Prof Xu, who is also a researcher at the NTU - Northwestern Institute for Nanomedicine, said their new method may solve some of the most pressing problems faced in chemotherapy used to treat cancer.

Researchers in nanomedicine have long dreamed of an age when molecular - scale computing devices could be embedded in our bodies to monitor health and treat diseases before they progress.

The point was further emphasized in a press release put out by Nature Nanotechnology this week: «These findings suggest that direct and indirect effects of nanoparticles on cells are equally crucial when considering the potential risks of their use in nanomedicine.»

He is co-director of the Jonsson Comprehensive Cancer Center Cell Biology Program Area and co-director for the UCLA Center for Cell Control, a NIH Roadmap Initiative Nanomedicine Development Center.