It has been known for a number of years that particular genetic variations are of importance for the functioning
of neural circuits in the brain.
These developmental defects in the
wiring of neural circuits cause very selective alterations in spatial learning and memory in adult mice.
Her lab explores the relationship between the
aging of neural circuits, the accumulation of toxic proteins and the subsequent activation of a chronic inflammatory response.
The group went on to simulate and evaluate a variety
of neural circuits by combining computational and biological approaches.
Such an improvement in learning makes a start at the brain and works in tandem with neurons in delivering greater motor control through better
management of neural circuits.
Psilocybin, a hallucinogenic compound found in magic mushrooms, may help re-set the
activity of neural circuits in the brain that are involved in depression
«There are patterns at every stage of life that are different from the patterns at other stages, and with the system we created we can see that really clearly in ways that are surprisingly complex and robust,» says Bargmann, who is the Torsten I. Wiesel Professor and head of the Lulu and Anthony Wang
Laboratory of Neural Circuits and Behavior.
In the Lu laboratory, we aim to elucidate the signaling cascades that establish neural circuit connections during brain development, to understand how sensory experiences and environmental factors affect neural circuit wiring and cognitive behaviors, and to identify novel factors required to maintain the health
of neural circuits during aging.
The work of Rakic and Jessell has provided, for the first time, a general framework for understanding the assembly
of neural circuits within the mammalian brain.
Sten Grillner has elucidated basic
principles of neural circuit organization and function that control vertebrate locomotion using lamprey as a model organism.
He hopes the study, «Activity of the C. elegans egg - laying behavior circuit is controlled by competing activation and feedback inhibition,» will lead to more insights on the
mechanics of neural circuits.
In the brain, these proteins assume an entirely different role, helping to regulate neuroplasticity — the
ability of neural circuits to reshape themselves at every stage of life.
«This and previous studies show that connectivity
of the neural circuits of two different species of sea slugs differ substantially from each other despite the presence of homologous neurons and behaviors.
Over the last ten years, Dr. Anderson has switched his research focus to the
study of neural circuits that control emotional behaviors in animal models.
Her research focuses on the signaling cascades underlying neural circuit connections during brain development, to understand how sensory experiences affect neural circuit wiring, and to identify novel factors required to maintain the
health of neural circuits during aging.
Chia - Shan Wu, Carlos J. Ballester Rosado, Hui - Chen Lu (2011) «What can we get from «BARRELs» - the rodent barrel cortex as a model to study the
establishment of neural circuits», European J. Neuroscience, 34:1663 - 76.
It's kind of chilling when you begin to suspect that such things are explainable as perhaps inevitable consequences of being the kind of creatures that we are — that we might point to some part of the brain and say it resides there as nothing more than a convoluted
net of neural circuits.
«I hope the procedure will be helpful for deriving the
parameters of neural circuits such as their connectivities, so that an incoming oscillation will trigger several different types of responses,» said Alonso.
The team suspected the mice had undergone a
kind of neural circuit workout — the repeated winning had perpetuated their drive to win.
The proposed institute would engage a dozen or more research groups in the task of figuring out how human or animal behavior springs from information processing at the
level of neural circuits.
Only by integrating the
investigation of neural circuit assembly, structure and function can we then really have a chance to comprehend how the brain as a whole gives rise to those sophisticated phenomena that make us who we are,» Donato said.
A new study by researchers at Roche in Basel, Switzerland has identified a key brain
region of the neural circuit that controls social behavior.
Published in Neuron, scientists at Cold Spring Harbor Laboratory (CSHL) report their
discovery of a neural circuit in the mouse olfactory bulb that explains how our mammalian cousins (and by extension, we) are able to adjust the gain on intense odors.
Brain Institute demonstrates in songbirds the
necessity of this neural circuit to learn vocalizations at a young age, a finding that expands the scientific understanding of some contributing factors in speech disorders in humans.
Dr. Britt obtained these results using optogenetics, which use light - responsive proteins to study the
activation of neural circuits in distinct locations, allowing the researcher to precisely dissect the roles of different neural circuits in the brain.
Compensating for random neural noise has shaped the human brain — and human intelligence — from the bottom up: the size and shape of neurons, the wiring
pattern of neural circuits, and even the language of spikes that encodes information.
Mead's students read biological journals religiously and then attempted to construct silicon
versions of the neural circuits that brain scientists were mapping out.
Our method is a first step toward developing a new mathematical toolkit to uncover the
structure of neural circuits with unknown function in the brain.»
Understanding the dynamic mechanisms that lead to the emergence of brain functions through the development and continuous
remodelling of neural circuits, and the constraints that disease and aging impose to this multi-modal plasticity has important implications that go beyond fundamental neuroscience, from education policies to brain repair.
The Max Planck Florida Institute for Neuroscience (Florida, USA) specializes in the development and application of novel technologies for probing the structure, function and
development of neural circuits.
As the use of neural implants moves toward treating cognitive disorders, one advantage of including microstimulation is the precise spatial targeting it affords, allowing for highly - controlled
manipulation of neural circuits.
Cho also explained that multiple projections from single neurons appear to be a general
feature of the neural circuits in the brain and could promote synchronized neural activity and long - term changes in the efficiency of neural communication.
So we've begun to delineate not only the sensory pathway but also the central
components of the neural circuit that is activated when the male encounters an animal from another species.»