Now, researchers may finally understand an important mechanism that keeps this friendly truce intact — a finding that may lead to the development
of new therapeutic strategies for such chronic diseases.
The review's authors, Dr Jessica Quimby, of the Department of Veterinary Clinical Sciences at Ohio State University, and Dr Dori Borjesson, of the Veterinary Institute for Regenerative Cures at the University of California - Davis, consider the
emergence of this new therapeutic strategy and the current understanding of the biology and immunology of mesenchymal stem cells.
The research, led by researchers from the Department of Pathology and Experimental Therapeutics of the Faculty of Medicine and Health Sciences of the University of Barcelona and the Bellvitge Biomedical Research Institute (IDIBELL), contributes to increase the knowledge about this complex and multi-factor inflammatory disease and opens doors to the development
of new therapeutic strategies.
We hope that the discovery of the mechanism that partly or totally explains the genesis of this genomic instability will eventually lead to the development
of new therapeutic strategies,» concludes Morgane Macheret.
This discovery could lead to the development
of new therapeutic strategies to control overactive inflammation, Li said.
The understanding of cell identity, heterogeneity and plasticity in neuroblastoma has strong implications with respect to the development
of new therapeutic strategies to eradicate tumor cells in neuroblastoma patients.
Multi-disciplinary translational research programs focused on the identification and development of new therapeutic strategies