Physical activity, mental health, and weight gain in a longitudinal observational cohort
of nonobese young adults
In fact, insulin resistance is present in ∼ 25 %
of nonobese people with normal glucose tolerance (30).
Effect of calorie restriction on the free - living physical activity levels
of nonobese humans: results of three randomized trials.
Not exact matches
The RR
of excess neonatal weight loss associated with delayed OL was similar and significant in both
nonobese and obese women (Figure 2).
Numbers
of participants in
nonobese [BMI (in kg / m2): < 30] and obese (BMI ≥ 30.0) groups, respectively, are as follows: timely OL (□; n = 102 and 34) and delayed OL (▪; n = 49 and 33)[P < 0.0001 within the
nonobese BMI group and P = 0.001 within the obese BMI group (chi - square analysis); Breslow - Day test for homogeneity
of the odds ratios (P = 0.6267), indicating that there was not a significant difference by BMI group in the association between delayed OL and excess neonatal weight loss].
One
of the most popular models is the immunodeficient
nonobese diabetic severe combined immunodeficiency (NOD scid) gamma (NSG) transgenic mouse line, which can be endowed with a humanized immune system using CD34 + hematopoietic stem cells.
One French study involving
nonobese diabetics found that a version
of a gene for a protein that transports zinc in the pancreas increased the risk
of this disease.
The physiological basis
of this variation was investigated by measuring changes in energy storage and expenditure in 16
nonobese volunteers who were fed 1000 kilocalories per day in excess
of weight - maintenance requirements for 8 weeks.
Because PD - L1 / programmed cell death (PD - 1) deficiency accelerates development
of diabetes in mouse models, Nasr et al. hypothesized that a defect in the PD - L1 / PD - 1 pathway may underpin the hyperglycemia observed in the
nonobese diabetic (NOD) mouse model.
'' (as the two independent demonstrations that resveratrol does not extend lifespan in
nonobese, wild - type mice over a wide range
of doses)» - Michael
And the claim typically persists for decades once widely - cited, despite the best efforts
of serious investigators to critique weak methodologies and flawed interpretation, or even robust demonstrations
of a null effect in healthy animals (as the two independent demonstrations that resveratrol does not extend lifespan in
nonobese, wild - type mice over a wide range
of doses).»
Since the unrelated NGT subjects have a broad BMI range, we further examined the impact
of obesity on the expression
of these six genes by comparing
nonobese and obese NGT subjects.
E: Comparison
of mRNA expression levels in adipose tissue from
nonobese (BMI < 30 kg / m2, n = 40) and obese (BMI > 30 kg / m2, n = 30) NGT subjects.
Gender factors affect fatty acids - induced insulin resistance in
nonobese humans: effects
of oral steroidal contraception
Continuous lines represent the normal metabolic condition (NGT) in both
nonobese and obese males and females, ie, for declining insulin sensitivity, there is an increase
of insulin secretion to compensate for insulin resistance, maintaining NGT (200).
Systemic delivery
of TNF - related apoptosis - inducing ligand (TRAIL) elevates levels
of tissue inhibitor
of metalloproteinase - 1 (TIMP - 1) and prevents type 1 diabetes in
nonobese diabetic mice.
These phenotypes were observed in obese and
nonobese males, indicating that obesity was not the cause
of those phenotypes.
Frankenfield D, Roth - Yousey L, Compher C. Comparison
of predictive equations for resting metabolic rate in healthy
nonobese and obese adults: a systematic review.
Ibanez L, Potau N, Marcos MV, de Zegher F. Treatment
of Hirsutism, Hyperandrogenism, Gligomenorrhea, Dyslipidemia, and Hyperinsulinism in
Nonobese, Adolescent Girls: Effect
of Flutamide.
It is possible that the subcutaneous fat, which is known to store vitamin D3, sequestered more
of the cutaneous synthesized vitamin D3 in the obese than in the
nonobese subjects because there was more fat available for this process.
There was no relation between basal vitamin D2 concentrations and 25 (OH) D. Peak blood concentrations
of vitamin D2 were not significantly different between the obese and
nonobese subjects.
One
of these trials was a 12 - wk study
of weight loss in 32
nonobese individuals, which confirmed the loss
of 6.5 %
of body weight in the ADF intervention arm compared with the nonfasting control arm (36).
Small studies
of obese and
nonobese individuals found that weight was lower by 2.5 — 8 % after 3 — 8 wk
of ADF (25, 27 — 29).
The opening line
of their discussion reads: «Alternate day fasting may adversely affect glucose tolerance in
nonobese women but not in
nonobese men.»
Gastro - intestinal effects and energy value
of polydextrose in healthy
nonobese men.