Sentences with phrase «of normal cells»

Free radicals are highly damaging by - products of normal cell chemistry.

However, direct evidence that fusion of normal cells by itself could trigger cancer has not been reported.

Because cancer cells grow and divide more rapidly than most of the normal cells around them, radiation therapy can successfully treat many kinds of cancer.

In 4 percent of cases, female flies were born with patches of normal cells and patches of yellow cells.

But the protein can also change the genetic sequence of a normal cell, altering the body's blueprint and making mutations that cause cancers.

When the mix of cells was three abnormal cells to one normal cell, some of abnormal cells continued to survive, but the ratio of normal cells increased.

Cancer, also called neoplasia, is the uncontrolled transformation of normal cells into abnormal ones, which usually form masses, invade nearby tissue and ultimately spread to other areas of the body.

FeLV can cause cancer by directly promoting transformation of normal cells into cancerous cells, and by causing significant immunosuppression, which makes a cat more vulnerable to both infections and cancer.

This protein is essential for the growth of normal cells, but is hyperactive in tumor cells.

Although fusion of normal cells in vitro and in vivo may be a rare event, this study shows that cell fusion between normal cells can have pathological consequences,» commented noted authority and cancer specialist William B. Coleman, Ph.D., of the Department of Pathology and Laboratory Medicine, Program in Translational Medicine at the University of North Carolina Comprehensive Cancer Center (Chapel Hill).

The transition from glucose to ketone bodies as an energy source is an ancestrally conserved adaptation to food deprivation that permits the survival of normal cells during extreme shifts in nutritional environment.

According to Eckmann, «The special thing about these processes is that they involve known molecules with very long evolutionary histories, previously receiving attention as suppressors of tumour formation within the context of normal cell division.

The research suggests that reducing production of the protein, called myoferlin, affects cancer cells in two primary ways: by changing the activation of many genes involved in metastasis in favor of normal cell behavior, and by altering mechanical properties of cancer cells — including their shape and ability to invade — so they are more likely to remain nested together rather than breaking away to travel to other tissues.

Cancer Center invesigators find that abnormal methylation disables tumor suppressor genes, leading to the loss of normal cell function.

The signs that we see in dogs are usually related to decreased numbers of normal cells (such as red blood cells which carry oxygen, white blood cells that fight infection and platelets that help with clotting) which are made in the bone marrow.

These U1 proteins are normally seen in the nucleus of normal cells, but in Alzheimer's brains they accumulated in tangle - like structures.

They also found that placing cells with low RasG12V expression at the end of a tube of normal cells allowed the mutant cells to branch and grow, drawing normal cells behind them like a bud at the tip of a growing tree branch.

Telomerase is an enzyme responsible for the production of telomeres, which play an important role in the regulation of normal cell division.

The berry is high in vitamins and antioxidants, including various polyphenols - compounds that are believed to mop up the harmful by - products of normal cell activity.

«The potency of these engineered macrophages is relatively clear, but the crucial issue is how to maximize the anti-cancer effects while minimizing side effects, namely the engulfment of normal cells.»

However, the T cells» alarm can be muted by so - called immune checkpoints, other proteins on the surface of normal cells that tamp down the immune response to prevent harmful autoimmune reaction to normal tissue.

This image shows differential susceptibility of normal cells (left) and cancer cells (right) to vtamin C.

Master heat - shock factor supports reprogramming of normal cells to enable tumor growth and metastasis

We developed SomaticSniper to detect somatic mutations in whole - genome sequencing data while allowing for tumor contamination of normal cells that occurs in some types of leukemia.

A protein known to play a role in transporting the molecular contents of normal cells into and out of various intracellular compartments can also turn such cells cancerous by stimulating a key growth - control pathway.

Cyclotherapy is a prospective therapeutic strategy for the protection of normal cells from the side effects of chemotherapy [17].

Cancer cells are like the spoiled siblings of normal cells, running rampant with unrestricted growth.

Gu's AβCs are constructed with a simplified version of a normal cell's two - layered lipid membrane.

Cancer cells are born of normal cells, a kinship that until now has caused many of our therapies to wreak havoc with the health and welfare of cancer patients.

We propose a different approach to brain cancer management that exploits the metabolic flexibility of normal cells at the expense of the genetically defective and metabolically challenged.

Antioxidants neutralize free radicals as the natural by - product of normal cell processes.

Positive effects where ROS mediate functions of normal cell metabolism include the induction of host defence genes and mobilisation of ion transport systems, and roles in redox signaling.

But in some cases, an acidic diet can make this bacteria highly aggressive and it can literally drill itself inside of a normal cell to get away from the acidity in the blood, as discovered by Robert O. Young, Ph.D..

Free radicals are known to wreak havoc on cells, the most common effect being the conversion of normal cells into cancer cells.

There it will destroy the abnormal cells that are overproducing thyroid hormone, sparing normal cells in the thyroid gland, as well as the rest of the normal cells in the body.

This means that abnormal blood cells can be produced or that production of normal cells can be halted due to an action of chloramphenicol on patient bone marrow.

«Our study also highlights that growth of normal cells and cancer cells is driven by different gene switches, suggesting that further work to find ways to control the activity of such disease - specific switches could lead to novel, highly specific approaches for therapeutic intervention», says Professor Jussi Taipale, who led the study.

We reasoned that if the hypothesis was correct, we might be able to find the src gene (the oncogene of the Rous sarcoma virus) in the DNA of normal cells.

It will be of no use to invent means for impeding the activities responsible for cancerous growth if the same activities are also required for the survival of normal cells.

Cancer arises from the transformation of normal cells into tumour cells in a multistage process that generally progresses from a pre-cancerous lesion to a malignant tumour.

Canine Thyroid Disease Example of Hyperplastic thyroid (abnormal increase in the number of normal cells) from an iodine - deficient dog Source: Washington State University

These compounds, widely present in fruits, vegetables and grains, were found to be much more effective in suppressing the growth of tumor cells than that of normal cells.

The atlas is NCI's mammoth effort to sequence the DNA of normal cells and tumor cells from 10,000 people with 20 types of cancer.

Their storage capacity is up to 1000 times higher than that of any normal cell of the leaf surface.

Only by understanding the behavior of normal cells, she maintained, would scientists learn how to prevent abnormal behaviors, such as cancer.

This work focuses on the mechanisms that underlie fundamental processes such as cell growth, the transformation of normal cells to cancer cells, and the spread, or metastasis, of cancer cells.

When they caused FATP4 to be expressed in cells that do not normally make this protein, these cells increased their uptake of fatty acids in a manner that resembled that of normal cells.