J147 increases the levels of BDNF in the hippocampus
of normal rats, as well as in huAPP / PS1 transgenic mice [7], and its synthetic precursor, CNB - 001, increases BDNF levels in rat traumatic brain injury models [54].
Octopamine has been identified in several organs
of normal rats by means of a sensitive enzymatic assay.
For most of the cancer cells, 45 — 100 nM RIPK2 inhibitor 1 inhibited > 70 % of the proliferation of colon and blood cancer cells while preserving the proliferation
of normal Rat - 1 and ModeK intestinal epithelial cells (Fig. 6A).
The concentration of in - situ antibody - AChR complexes was determined by precipitation with goat anti-rat serum in the presence
of normal rat serum.
Not exact matches
Studies with
rats have found that even short bursts
of such hormones during pregnancy can result in
normal genitals accompanied by transgender behaviour.
Throughout the course
of the experiment, the
rats getting capsaicin gained 8 percent less weight than untreated animals, and just a little more weight than
rats eating a
normal diet.
None
of the
rats died and they all appeared
normal throughout the study.
In a similar study,
rats were fed crude extracts
of chile pods and crystalline capsaicinoids by stomach tube while allowed access to
normal food and water.
Normal research based on coconut oil would entail a special diet being prepared from coconut oil and fed to animals (
rats and pigs), but this would be done without proper knowledge on the type
of coconut oil used and the composition
of the non-lipid fraction, according to him.
The
rats were randomly assigned into the control group with
normal feed and saline only, and three groups with virgin coconut oil (VCO)
of varying amounts added to
normal feed.
The title
of the study is: Dietary Supplementation with Virgin Coconut Oil Improves Lipid Profile and Hepatic Antioxidant Status and Has Potential Benefits on Cardiovascular Risk Indices in
Normal Rats.
In a similar study,
rats were fed crude extracts
of chile pods and crystalline capsainoids by stomach tube while allowed access to
normal food and water.
Rats deprived
of sleep lose the ability to regulate metabolism — they eat twice the
normal amount
of food, but still lose weight.
In the 1930s researchers discovered that laboratory
rats fed a limited diet live about 40 % longer than
normal and are resistant to many chronic illnesses typical
of aging.
A North Carolina State University - led research team has shown a connection between exposure to a widely used flame retardant chemical mixture and disruption
of normal placental function in
rats, leading to altered production
of the neurotransmitter serotonin.
Researchers at Mount Sinai School
of Medicine in New York City report that one or two treatments with a compound called RU38486 can disrupt traumatic memories in
rats without affecting
normal memories.
The team found a smaller aura
of activity originating from the curved dentate gyrus than in
normal rats [see image below].
When «depressed» mice and
rats were given ketamine, the number
of bursting cells was much lower, similar to the number in
normal animals, Hu's team found.
IBM developed a technique for making carbon nanotubes emit light, paving the way for new fiber optics; Harvard scientists figured out how to deposit tiny wires on glass or plastic, opening the door for the development
of supercheap computers; and at the University
of Central Florida, neuroscientist Beverly Rzigalinski discovered a nanomolecular fountain
of youth effect: When Rzigalinski applied cerium oxide nanoparticles to
rat neurons in a petri dish, the particles seemed to strip out the free radicals that make tissues age and kept the neurons alive and functioning up to six times their
normal life span.
Naked mole
rats are unusual in many ways as a result
of adaptations to living underground, with extreme longevity and a lack
of the
normal signs
of aging.
Campbell chose to feed casein to
rats in
normal doses, with 15 to 20 percent
of their diet (by weight) coming from protein.
The double strands represented material from the
rat brain: either the Borna - disease brain, the
normal brain, or a combination
of the two.
Rats with an isolated CA1 area showed
normal acquisition
of an associative hippocampal - dependent spatial recognition task.
The researchers wanted to test the impact
of different conditions on the
rats» performance, so they placed the
rats in mazes that had «enriched», «
normal» or «restricted» environments.
Gore and her colleagues believe these effects are epigenetic; that is, rather than inducing genetic mutations, which would change the sequence
of the
rats» DNA, the fungicide is permanently silencing or reprogramming
normal genes that control development and behavior.
When transplanted into the testes
of rats or mice with hypogonadism, these cells survived and restored
normal testosterone levels.
Historically, the typical incidence
of gliomas and schwannomas in
normal rats has been about 2 per cent and 1 per cent, respectively.
«It's not obvious to me how these results from high doses in
rats can tell us anything yet about
normal levels
of human mobile phone use,» he says.
One idea is that
rats on a spartan diet keep their proteins turning over at higher rates than
normal, says Brian Merry, who is studying ageing and diet at the Institute
of Human Ageing in the University
of Liverpool.
First, Nakashima and his colleagues photographed three laboratory
rats as they sat in what he calls a «neutral» position — a kind
of normal, everyday, unruffled
rat pose.
The lab - grown exosomes stimulated myelin production in a sample
of rat brain tissue intended to simulate multiple sclerosis damage, returning myelin levels to 77 percent
of normal, Kraig and his colleagues recently reported in the Journal
of Neuroimmunology.
Yeast can also carry prions, and the duo fused part
of a yeast prion protein called Sup35 to a
normal rat protein that controls the transcription
of DNA into RNA.
After cultured
rat heart cells were infected with the Coxsackie B virus, the amount
of normal dystrophin declined within 3 days.
Rats born
of hypoxic pregnancy with no vitamin C treatment showed increased thickening
of the walls
of the aorta — up to 170 % above
normal — and molecular markers
of disease, such as an increase in the heart's heat shock proteins, a signal
of cardiac oxidative stress.
Both groups
of animals ate
normal lab -
rat chow throughout the experiment.
The exposure levels used in the
rat study were chosen to produce increases in manganese intake (relative to the
normal intake
of baby
rats) comparable to the relative increases that would be experienced by infants and young children exposed to contaminated drinking water, soy - based formulas, or both.
, Compartmental study
of diffusion and relaxation measured in vivo in
normal and ischaemic
rat brain and trigeminal nerve.
The lab recently developed an animal model
of BED in which
rats are given irregular, limited access to chocolate along with
normal chow.
Over a period
of 4 weeks,
rats develop robust, binge eating (BE)
of the chocolate with concomitant reduction in their intake
of normal chow and also showed increased impulsive behaviors.
Fxna, a novel gene differentially expressed in the
rat ovary at the time
of folliculogenesis, is required for
normal ovarian histogenesis.
Taxt T, Storm - Mathisen J (1984) Uptake
of D - aspartate and L - glutamate in excitatory axon terminals in hippocampus: autoradiographic and biochemical comparison with gamma - aminobutyrate and other amino acids in
normal rats and in
rats with lesions Neuroscience, 11 (1), 79 - 100 PubMed 6143283
Uptake
of D - aspartate and L - glutamate in excitatory axon terminals in hippocampus: autoradiographic and biochemical comparison with gamma - aminobutyrate and other amino acids in
normal rats and in
rats with lesions
This study investigated the influence
of chronically administered curcumin on
normal ageing - related parameters: lipid peroxidation, lipofuscin concentration and intraneuronal lipofuscin accumulation, activities
of the enzymes superoxide dismutase (SOD), glutathione peroxidase (GPx), and Na (+), K (+), - adenosine triphosphatase (Na (+), K (+), - ATPase) in different brain regions (cerebral cortex, hippocampus, cerebellum and medulla)
of 6 - and 24 - month - old
rats.
For the study, Hill compared brain tissue from
normal and Parkinson's - like
rats using ion mobility — mass spectrometry (IMMS), a process that analyzes both the weight and speed
of chemical molecules.
5/31/2007 Human Stem Cell Treatment Restores Motor Function in Paralyzed
Rats Rats paralyzed due to loss
of blood flow to the spine returned to near
normal ambulatory function six weeks after receiving grafts
of human spinal stem cells (hSSCs), researchers from the University
of California, San Diego (UCSD) School
of Medicine... More...
Sustained hyperleptinemia
of 8 ng / ml was induced for 28 days in
normal Wistar
rats by infusing a recombinant adenovirus containing the
rat leptin cDNA (AdCMV - leptin).
IHC image
of GFAP staining in a formalin fixed, paraffin embedded
normal rat brain tissue section, performed on a Leica Bond ™ system using the standard protocol F.
In the lab, Bub's group grew
normal cells from the heart muscle
of a
rat.
The culture system supports
normal differentiation
of the Sprague — Dawley
rat testes for 3 days (Habert et al., 1991) and has been validated for toxicological studies (Lassurguere et al., 2003; Chauvigne et al., 2009).
«If you only feed
rats for four hours a day, in the middle
of their
normal sleep cycle, they quickly adjust to be awake before the food arrives,» Clifford Saper, PhD, study author and professor
of neurology and neuroscience at Harvard Medical School wrote in an email to Health.