Sentences with phrase «of normal rats»

J147 increases the levels of BDNF in the hippocampus of normal rats, as well as in huAPP / PS1 transgenic mice [7], and its synthetic precursor, CNB - 001, increases BDNF levels in rat traumatic brain injury models [54].
Octopamine has been identified in several organs of normal rats by means of a sensitive enzymatic assay.
For most of the cancer cells, 45 — 100 nM RIPK2 inhibitor 1 inhibited > 70 % of the proliferation of colon and blood cancer cells while preserving the proliferation of normal Rat - 1 and ModeK intestinal epithelial cells (Fig. 6A).
The concentration of in - situ antibody - AChR complexes was determined by precipitation with goat anti-rat serum in the presence of normal rat serum.

Not exact matches

Studies with rats have found that even short bursts of such hormones during pregnancy can result in normal genitals accompanied by transgender behaviour.
Throughout the course of the experiment, the rats getting capsaicin gained 8 percent less weight than untreated animals, and just a little more weight than rats eating a normal diet.
None of the rats died and they all appeared normal throughout the study.
In a similar study, rats were fed crude extracts of chile pods and crystalline capsaicinoids by stomach tube while allowed access to normal food and water.
Normal research based on coconut oil would entail a special diet being prepared from coconut oil and fed to animals (rats and pigs), but this would be done without proper knowledge on the type of coconut oil used and the composition of the non-lipid fraction, according to him.
The rats were randomly assigned into the control group with normal feed and saline only, and three groups with virgin coconut oil (VCO) of varying amounts added to normal feed.
The title of the study is: Dietary Supplementation with Virgin Coconut Oil Improves Lipid Profile and Hepatic Antioxidant Status and Has Potential Benefits on Cardiovascular Risk Indices in Normal Rats.
In a similar study, rats were fed crude extracts of chile pods and crystalline capsainoids by stomach tube while allowed access to normal food and water.
Rats deprived of sleep lose the ability to regulate metabolism — they eat twice the normal amount of food, but still lose weight.
In the 1930s researchers discovered that laboratory rats fed a limited diet live about 40 % longer than normal and are resistant to many chronic illnesses typical of aging.
A North Carolina State University - led research team has shown a connection between exposure to a widely used flame retardant chemical mixture and disruption of normal placental function in rats, leading to altered production of the neurotransmitter serotonin.
Researchers at Mount Sinai School of Medicine in New York City report that one or two treatments with a compound called RU38486 can disrupt traumatic memories in rats without affecting normal memories.
The team found a smaller aura of activity originating from the curved dentate gyrus than in normal rats [see image below].
When «depressed» mice and rats were given ketamine, the number of bursting cells was much lower, similar to the number in normal animals, Hu's team found.
IBM developed a technique for making carbon nanotubes emit light, paving the way for new fiber optics; Harvard scientists figured out how to deposit tiny wires on glass or plastic, opening the door for the development of supercheap computers; and at the University of Central Florida, neuroscientist Beverly Rzigalinski discovered a nanomolecular fountain of youth effect: When Rzigalinski applied cerium oxide nanoparticles to rat neurons in a petri dish, the particles seemed to strip out the free radicals that make tissues age and kept the neurons alive and functioning up to six times their normal life span.
Naked mole rats are unusual in many ways as a result of adaptations to living underground, with extreme longevity and a lack of the normal signs of aging.
Campbell chose to feed casein to rats in normal doses, with 15 to 20 percent of their diet (by weight) coming from protein.
The double strands represented material from the rat brain: either the Borna - disease brain, the normal brain, or a combination of the two.
Rats with an isolated CA1 area showed normal acquisition of an associative hippocampal - dependent spatial recognition task.
The researchers wanted to test the impact of different conditions on the rats» performance, so they placed the rats in mazes that had «enriched», «normal» or «restricted» environments.
Gore and her colleagues believe these effects are epigenetic; that is, rather than inducing genetic mutations, which would change the sequence of the rats» DNA, the fungicide is permanently silencing or reprogramming normal genes that control development and behavior.
When transplanted into the testes of rats or mice with hypogonadism, these cells survived and restored normal testosterone levels.
Historically, the typical incidence of gliomas and schwannomas in normal rats has been about 2 per cent and 1 per cent, respectively.
«It's not obvious to me how these results from high doses in rats can tell us anything yet about normal levels of human mobile phone use,» he says.
One idea is that rats on a spartan diet keep their proteins turning over at higher rates than normal, says Brian Merry, who is studying ageing and diet at the Institute of Human Ageing in the University of Liverpool.
First, Nakashima and his colleagues photographed three laboratory rats as they sat in what he calls a «neutral» position — a kind of normal, everyday, unruffled rat pose.
The lab - grown exosomes stimulated myelin production in a sample of rat brain tissue intended to simulate multiple sclerosis damage, returning myelin levels to 77 percent of normal, Kraig and his colleagues recently reported in the Journal of Neuroimmunology.
Yeast can also carry prions, and the duo fused part of a yeast prion protein called Sup35 to a normal rat protein that controls the transcription of DNA into RNA.
After cultured rat heart cells were infected with the Coxsackie B virus, the amount of normal dystrophin declined within 3 days.
Rats born of hypoxic pregnancy with no vitamin C treatment showed increased thickening of the walls of the aorta — up to 170 % above normal — and molecular markers of disease, such as an increase in the heart's heat shock proteins, a signal of cardiac oxidative stress.
Both groups of animals ate normal lab - rat chow throughout the experiment.
The exposure levels used in the rat study were chosen to produce increases in manganese intake (relative to the normal intake of baby rats) comparable to the relative increases that would be experienced by infants and young children exposed to contaminated drinking water, soy - based formulas, or both.
, Compartmental study of diffusion and relaxation measured in vivo in normal and ischaemic rat brain and trigeminal nerve.
The lab recently developed an animal model of BED in which rats are given irregular, limited access to chocolate along with normal chow.
Over a period of 4 weeks, rats develop robust, binge eating (BE) of the chocolate with concomitant reduction in their intake of normal chow and also showed increased impulsive behaviors.
Fxna, a novel gene differentially expressed in the rat ovary at the time of folliculogenesis, is required for normal ovarian histogenesis.
Taxt T, Storm - Mathisen J (1984) Uptake of D - aspartate and L - glutamate in excitatory axon terminals in hippocampus: autoradiographic and biochemical comparison with gamma - aminobutyrate and other amino acids in normal rats and in rats with lesions Neuroscience, 11 (1), 79 - 100 PubMed 6143283
Uptake of D - aspartate and L - glutamate in excitatory axon terminals in hippocampus: autoradiographic and biochemical comparison with gamma - aminobutyrate and other amino acids in normal rats and in rats with lesions
This study investigated the influence of chronically administered curcumin on normal ageing - related parameters: lipid peroxidation, lipofuscin concentration and intraneuronal lipofuscin accumulation, activities of the enzymes superoxide dismutase (SOD), glutathione peroxidase (GPx), and Na (+), K (+), - adenosine triphosphatase (Na (+), K (+), - ATPase) in different brain regions (cerebral cortex, hippocampus, cerebellum and medulla) of 6 - and 24 - month - old rats.
For the study, Hill compared brain tissue from normal and Parkinson's - like rats using ion mobility — mass spectrometry (IMMS), a process that analyzes both the weight and speed of chemical molecules.
5/31/2007 Human Stem Cell Treatment Restores Motor Function in Paralyzed Rats Rats paralyzed due to loss of blood flow to the spine returned to near normal ambulatory function six weeks after receiving grafts of human spinal stem cells (hSSCs), researchers from the University of California, San Diego (UCSD) School of Medicine... More...
Sustained hyperleptinemia of 8 ng / ml was induced for 28 days in normal Wistar rats by infusing a recombinant adenovirus containing the rat leptin cDNA (AdCMV - leptin).
IHC image of GFAP staining in a formalin fixed, paraffin embedded normal rat brain tissue section, performed on a Leica Bond ™ system using the standard protocol F.
In the lab, Bub's group grew normal cells from the heart muscle of a rat.
The culture system supports normal differentiation of the Sprague — Dawley rat testes for 3 days (Habert et al., 1991) and has been validated for toxicological studies (Lassurguere et al., 2003; Chauvigne et al., 2009).
«If you only feed rats for four hours a day, in the middle of their normal sleep cycle, they quickly adjust to be awake before the food arrives,» Clifford Saper, PhD, study author and professor of neurology and neuroscience at Harvard Medical School wrote in an email to Health.
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