Sentences with phrase «of normal tissue»

The selection of a radiation dose is based on considerations of tumor type, tumor location, and on the tolerance of the normal tissues surrounding the tumor.

This means that a wide area of normal tissue around the tumor will be removed so that no cancer cells can be detected under a microscope from the margins of the tissue extracted.

This is done to minimize bacterial contamination of the normal tissue.

«Wide margin of normal tissue surrounding the cancer must be removed to help prevent recurrence.»

Therefore, the plan would pay only if a malignant tumour exhibits uncontrolled growth, with destruction of normal tissues at a very advanced stage.

He explains, «cadherins were mostly known for their role in the maintenance of normal tissue structure.

Israel and his team sought to understand the mechanisms that drive tumor invasion of normal tissue in glioblastoma.

Immunologist William Parker of Duke University examined samples of normal tissue from organ donors and from patients who had healthy appendixes removed during other surgeries.

These findings have significant implications to the understanding of normal tissue methylation and strongly indicate that events occurring before birth influence cancer risk later in life.

Opponents of circumcision argue the procedure can cause damage that ranges from nerve destruction and loss of normal tissue to infection, disfigurement and sometimes death.

«Our goal in a lumpectomy is to get the lump out with a small rim of normal tissue around it,» Dr. Lee said.

At the higher pH of normal tissues (around 7.2), however, heparanase was found to function in an entirely different way.

«The tumor is really like a caricature of normal tissue,» Snippert says.

Researchers from Haukeland University Hospital in Bergen, Norway, and colleagues analyzed for potential impact of normal tissue BRCA1 methylation on ovarian cancer risk.

The viscosity and elasticity of the tissue were similar to the viscosity and elasticity of normal tissue, further tests showed.

We have been fortunate to work in collaboration with the pharmaceutical company Pharmaxis, which is designing novel and highly selective small molecules that will allow the establishment of normal tissue architecture after wound repair.»

Next, Abadir and colleagues compared the effects of different concentrations of losartan and valsartan on young diabetic and aged mice during the proliferation / remodeling phase of wound healing, which involves the regrowth of normal tissue.

When activated, these cells multiply and then transform into other cell types required to replace worn out cells under conditions of normal tissue maintenance.

To the identify the tissue - wide expression pattern of this receptor, they screen the full human tissue atlas and find expression in a limited number of normal tissues and cancers, including some reproductive and lymphoid organs and cancers.

«With this new technique, we have successfully grown skin that replicates the function of normal tissue,» Tsuji said.

Tumor development to a certain degree resembles and has been compared as «caricatures» of normal tissue histogenesis and organogenesis (5).

Therefore, we hypothesized that NSCs could be used to enhance antibody - based therapies by delivering antibodies to previously inaccessible tumor foci, while minimizing the exposure of normal tissue to the therapeutic agent.

This latter postulate, called «cancer stem cell (CSC) hypothesis» was recently revived (10) mainly due to progress made on studies of normal tissue stem cells.

Another culprit can be polyps, which are an overgrowth of normal tissue in the uterus or cervix that may be caused by high estrogen levels.

When this problem occurs and no foreign agent is present, we call it an autoimmune phenomenon and assume that the cat's body mistakenly perceives some portion of its normal tissue as being a foreign agent.

These metabolic alterations include the inability of normal tissues to take up blood glucose because of their decreased sensitivity or decreased responsiveness to insulin; an increased protein degradation combined with a decreased protein synthesis; finally an increased activity of the enzymes involved in degradation and mobilization of lipids in body fat cells.

Talk to the surgeon that removed it - they will let you know if it looked odd and whether they feel like they were able to get good margins of normal tissue all the way around the tumor.

Commonly referred to as «cherry eye,» a prolapsed gland of the nictitating membrane (PGNM) is essentially a herniation, or a protrusion of normal tissue into an abnormal place.

When a focal cancerous mass is removed, the surgeon tries to also remove a small amount of normal tissue around the entire mass of abnormal tissue, in order to achieve what are called «clean surgical margins.»

These include complete removal of a tumor, partial removal of a tumor, or exploration of a particular area to obtain a sample of tumor tissue and evaluate the extent of normal tissue involvement.

The preferred treatment is to remove the tumor surgically with 0.5 - 1 cm margins of the normal tissue surrounding the tumor.

They also collect small samples of normal tissue.

However most veterinarians prefer to operate under general anesthesia, as a wide margin of normal tissue surrounding the cancer must be removed to help prevent recurrence.

«The anti-tumor activity seen in our study occurred prior to the destruction of normal tissue.

«Our study highlights the complexity of p38 functions, both in cancer and in the maintenance of normal tissues.

This is especially true because malignant tumors, like TCC, need to be removed with a «margin» of normal tissue around the tumor.

«Stronger absorption from the cervical lesions is observed compared to that of normal tissue,» Xiao said.

Although these minute specks can be obscured by the wealth of information contained in a typical mammogram, the University of Chicago research team has taught the computer to recognize these stars, even through the «clouds» of normal tissue, and to alert the radiologist to their presence.

Incisions were made and the dog lumps and bumps, including some of the normal tissue surrounding them, were removed completely.

Canine neoplasia is an abnormal mass of tissue, the growth of which exceeds and is uncoordinated with that of the normal tissues, and persists in the same excessive manner after cessation of the stimulus which evoked the change.

Eventually, all of the normal tissue was gone, leaving the dog with an open wound over the entire nose.