Her research may lead to improved diagnostic tools and also facilitate the development
of novel cancer therapies that prevent tumor recruitment of macrophages and, as a result, impair a cancer's ability to metastasize.
Christopher Flowers, M.D. Emory University Microsimulation modeling to evaluate the clinical effectiveness
of novel cancer therapies
The integrated approaches being developed and used at Moffitt are instrumental for the continued advancement of our understanding of cancer progression and the development
of novel cancer therapies.
Not exact matches
The falling rate
of cancer - related deaths is clearly an impressive achievement, and may be partially attributable to drug makers» increased focus on developing
novel new
therapies to fight
cancers.
«It is anticipated that this
novel compound will have significant efficacy in human melanomas and other
cancers either as a stand - alone
therapy or in combination with other targeted or immune - based
therapies,» explained co-corresponding author Rhoda Alani, MD, the Herbert Mescon Chair
of Dermatology at Boston University School
of Medicine (BUSM).
Researchers at The University
of Texas MD Anderson
Cancer Center developed a
novel chimeric mouse model to test the combination
therapy using immune checkpoint blockades with
therapies targeting myeloid - derived suppressor cells (MDSCs).
This is important because it makes it possible to model almost any autoimmune disease, evaluate new drug
therapies, and even identify
novel targets in the emerging area
of cancer immunotherapies.
Physical chemist Bartosz Grzybowski
of Northwestern University in Evanston, Illinois, and colleagues hit upon the droplets while trying to devise
novel cancer therapies.
In a letter to the New England Journal
of Medicine, a Massachusetts General Hospital (MGH) research team reports a remarkable treatment response in a patient participating in a clinical trial
of a
novel immune - system - based
cancer therapy.
Meanwhile, his research teams are moving several other
novel therapies toward clinical trials, each
of which has potential for use in the synergistic model
of cancer treatment that Black believes will offer the best hope for his patients.
The study, «Non-toxic metabolic management
of metastatic
cancer in VM mice:
novel combination
of ketogenic diet, ketone supplementation, and hyperbaric oxygen
therapy,» was published online today in PLOS ONE.
A team
of researchers from the Hyperbaric Biomedical Research Laboratory at the University
of South Florida (USF) doubled survival time in an aggressive metastatic
cancer model using a
novel combination
of non-toxic dietary and hyperbaric oxygen
therapies.
It's the first CAR - T
therapy to come before the FDA, leading a pack
of novel treatments that promise to change the standard
of care for certain aggressive blood
cancers.
Investigators with The
Cancer Genome Atlas (TCGA) Research Network have identified novel genomic and molecular characteristics of cervical cancer that will aid in the subclassification of the disease and may help target therapies that are most appropriate for each pa
Cancer Genome Atlas (TCGA) Research Network have identified
novel genomic and molecular characteristics
of cervical
cancer that will aid in the subclassification of the disease and may help target therapies that are most appropriate for each pa
cancer that will aid in the subclassification
of the disease and may help target
therapies that are most appropriate for each patient.
Timothy Wang at Columbia recently published work in
Cancer Cell (DOI: 10.1016 / j.ccell.2016.11.005) that showed that recruitment of nerves into the tumor microenvironment is necessary and sufficient for stomach cancer progression, and that blocking a neurotransmitter in the nerves that line the stomach could represent a novel th
Cancer Cell (DOI: 10.1016 / j.ccell.2016.11.005) that showed that recruitment
of nerves into the tumor microenvironment is necessary and sufficient for stomach
cancer progression, and that blocking a neurotransmitter in the nerves that line the stomach could represent a novel th
cancer progression, and that blocking a neurotransmitter in the nerves that line the stomach could represent a
novel therapy.
These
therapies could enhance the effects
of novel cancer immunotherapies when used in combination, resulting in better health outcomes for
cancer patients.
«A better understanding
of how inflammation affects stem cells and other components
of tissue will revolutionize our understanding
of many diseases, including
cancer, and likely lead to
novel therapies,» Naik says.
Coupled with a review
of these results by experts on a molecular tumor board, the opportunity exists to identify
novel therapies that would target specific abnormalities,» notes senior author
of the work, Shridar Ganesan, MD, PhD, associate director for translational science at Rutgers
Cancer Institute and associate professor
of medicine and pharmacology at Rutgers Robert Wood Johnson Medical School.
Axel Huebl, who joined the team a year after Burau, has pushed the code to make optimal use
of all
of Titan's GPUs, winning him time on Titan through DOE's Innovative and
Novel Computational Impact on Theory and Experiment (INCITE) program for his PhD research on laser - driven radiation
therapy of cancer.
«We are currently identifying the genes responsible for generating the DNA tether, which could be promising
novel targets for the next generation
of cancer therapies.»
Moffitt
Cancer Center researchers are leading the way in the creation
of novel therapies.
New studies from the Abramson
Cancer Center of the University of Pennsylvania are providing fresh clues on potentially effective combinations with CAR T therapy in brain cancer as well as a novel therapeutic target in head and neck cancer, and also providing greater understanding of the mechanisms of resistance in pancreatic c
Cancer Center
of the University
of Pennsylvania are providing fresh clues on potentially effective combinations with CAR T
therapy in brain
cancer as well as a novel therapeutic target in head and neck cancer, and also providing greater understanding of the mechanisms of resistance in pancreatic c
cancer as well as a
novel therapeutic target in head and neck
cancer, and also providing greater understanding of the mechanisms of resistance in pancreatic c
cancer, and also providing greater understanding
of the mechanisms
of resistance in pancreatic
cancercancer.
«This will help us better understand the biology
of cancer, guide therapeutic decisions and develop
novel therapies.»
Their findings, to be published in the July issue
of the journal
Cancer Cell, could explain why some tumors don't respond to radiation or chemotherapy, and provide
novel routes for the development
of new anti-
cancer therapies.
The Department
of Translational Hematology and Oncology Research (THOR) conducts
cancer research to develop and make available
novel diagnostic tools, targeted
therapies and clinical trials for direct use in patient care.
In my role as a Clinical Professor
of Medicine, Jacobs School
of Medicine and Biomedical Sciences, University at Buffalo, Professor
of Medicine and Director
of Early Phase Clinical Trials Program in the Department
of Medicine at Roswell Park Comprehensive
Cancer Center, I am developing novel therapies for patients with c
Cancer Center, I am developing
novel therapies for patients with
cancercancer.
For their collective contributions to the pre-clinical foundation and development
of immune checkpoint blockade, a
novel form
of cancer therapy that has transformed the landscape
of cancer treatment.
The work being done by scientists at Longevica may lead to a
novel approach in
cancer therapy that can significantly improve the efficiency
of the current methods
of cancer treatment.
Major focus areas include human genome interpretation and genetic dissection
of novel rare diseases, predictive genomic signatures
of response to
therapy — especially
cancer therapy, and
novel sequencing - based assays as biomarkers
of disease.
«Dr. Meyers» research is a perfect example as to how fundamental laboratory studies are leading to innovative and
novel therapies for breast
cancer treatment,» says Dr. Raymond Hohl, director of the Penn State Hershey Cancer Inst
cancer treatment,» says Dr. Raymond Hohl, director
of the Penn State Hershey
Cancer Inst
Cancer Institute.
More recently, he has focused on triple - negative breast
cancer, the role
of micro-RNAs in
cancer growth and metastasis, tumor heterogeneity and
novel approaches to targeting
therapy - resistant breast
cancers.
Through understanding the biology
of cancer cells and their interaction with the immune system we are able to discover and trial
novel therapies to induce the immune system to detect and fight
cancer cells.
GigaGen's proprietary approach delivers unprecedented insights into immune regulatory pathways and what causes them to fail, enabling a pipeline
of novel antibody
therapies for patients with
cancer and immune deficiency diseases.
These combined clinical and laboratory resources accelerate the development
of novel therapeutics, including immune
therapies — resulting in optimized, personalized
cancer treatments.
The South Florida Bone Marrow / Stem Cell Transplant Institute is now running a new clinical trial protocol (08001 - BMSCTI) for investigating a
novel cancer therapy using transfusions
of white blood cells from healthy donors.
These
therapies are now being tested in various type
of cancer and
novel combination approaches are being developed at a very fast pace.
The Maharaj Institute has an FDA IND clinical trial protocol (08001 - BMSCTI) for investigating a
novel cancer therapy using transfusions
of white blood cells from healthy donors to patient with advanced solid tumors.
«RapidCaP, a
novel GEM model for analysis and
therapy of metastatic prostate
cancer reveals Myc as a driver of Pten - mutant metastasis» appears online in Cancer Discovery on January 21,
cancer reveals Myc as a driver
of Pten - mutant metastasis» appears online in
Cancer Discovery on January 21,
Cancer Discovery on January 21, 2014.
The results
of her project will help scientists develop
novel therapies to target the regulatory proteins that cause CD47 overproduction in leukemia and other
cancer stem cells, with the goal
of restoring immunosurveillance and enabling the immune system to recognize and destroy these aberrant
cancer cells.
Clinical Trials Research and Billing First in Human / Early Phase PET in Oncology Case - Based Dose Reduction in Pediatric Nuclear Medicine: Practical and Necessary Radioiodine
Therapy for Hyperthyroidism: The State
of the Art Spondylodiscitis: Role
of Imaging for Diagnosis and Monitoring Treatment Response Current Status and Future Prospects: PET and SPECT Instrumentation Alternative Payment Models and Value - Based Health Care: Nuts and Bolts Maximal Tolerated Activity
of Radioactive Iodine for Metastatic Thyroid
Cancer Teaching Old Radiopharmaceuticals New Tricks Intraoperative Detection Devices and Probes Molecular Imaging
of Lung Inflammation Standardization
of Advanced PET / SPECT Data Acquisition and Analysis Thyroid
Cancer Management:
Novel Therapeutics and Management Options Targeting Radionuclide
Therapy in Various Non-Malignant Arthritic Conditions Using Radiosynoviorthesis (RSO) Are You Prepared for a Radiation Accident?
A bioengineer in the College
of Engineering and Computer Science at Florida Atlantic University has received a $ 141,743 grant from the National
Cancer Institute of the National Institutes of Health to develop a novel biodegradable polymer stent that will be designed to prevent complications while at the same time serving as a drug delivery system for esophageal cancer th
Cancer Institute
of the National Institutes
of Health to develop a
novel biodegradable polymer stent that will be designed to prevent complications while at the same time serving as a drug delivery system for esophageal
cancer th
cancer therapy.
Personalized Blood Test Monitors Success
Of Cancer Therapies Johns Hopkins Kimmel
Cancer Center researchers developed a
novel test to measure tumor - derived DNA in the bloodstream.
The goal
of this Center
of Excellence is to better define thrombus development in patients with
cancer, test the efficacy
of novel therapies, develop new preclinical models, and create and expand biorepositories to provide a valuable resource to researchers across Cleveland Clinic.
My studies
of cancer genomes have led to characterization
of multiple pediatric and adult tumor types, to development
of methods that identify and characterize changes in genomic heterogeneity, to defining acquired resistance mechanisms to targeted
therapies and to designing
novel, personalized vaccines for individual patients.
These studies support the idea that nutrient transporters can be exploited as potential drug targets for
cancer therapy and usher us into a new era
of novel cancer therapeutics beyond kinase inhibitors and growth factor receptor blockers.
12 Scientific Sessions Radiochemistry: Imaging
of Cancer Other Tumors Basic Science Summary Session One Myeloma and Other Marrow Disorders Radiopharmacy: Quality Control and Validation Radiotherapy and Monitoring
Therapy Basic Science Summary Session Two Pre-Clinical Systems Breast
Cancer Prostate I: Initial Staging Quantification and Methodology
of Oncology Studies
Novel Radiochemistry: Radiometals
Novel drug therapies and novel indications of drug therapy, e.g. tyrosine kinase inhibitors in lung disease other than lung cancer, biological treatments for asthma, COPD, cystic fibrosis and interstitial lung dis
Novel drug
therapies and
novel indications of drug therapy, e.g. tyrosine kinase inhibitors in lung disease other than lung cancer, biological treatments for asthma, COPD, cystic fibrosis and interstitial lung dis
novel indications
of drug
therapy, e.g. tyrosine kinase inhibitors in lung disease other than lung
cancer, biological treatments for asthma, COPD, cystic fibrosis and interstitial lung disease.
The King lab is currently testing these
novel cancer therapies in mouse models
of metastatic breast and prostate
cancer through the use
of whole body luminescence imaging.
5/7/2007 Targeting Sugar on Blood Vessels May Inhibit
Cancer Growth In a study that could point to novel therapies to prevent cancer spread, or metastasis, researchers at the University of California, San Diego (UCSD) School of Medicine have targeted a sugar that supports blood vessel growth in the
Cancer Growth In a study that could point to
novel therapies to prevent
cancer spread, or metastasis, researchers at the University of California, San Diego (UCSD) School of Medicine have targeted a sugar that supports blood vessel growth in the
cancer spread, or metastasis, researchers at the University
of California, San Diego (UCSD) School
of Medicine have targeted a sugar that supports blood vessel growth in the tumor.
In honor
of James Allison, Lieping Chen, Gordon Freeman, Tasuku Honjo and Arlene Sharpe for contributions to the pre-clinical foundation and development
of immune checkpoint blockade, a
novel form
of cancer therapy that has transformed the landscape
of cancer treatment.