Fernández warns, «Given the obesity epidemic in the US and worldwide, an increase in those affected by non-alcoholic fatty liver disease is expected in the coming decades and we still do not have a suitable treatment for this condition; A fundamental understanding of this medical problem is therefore essential for development
of novel treatment strategies.»
They integrated university -, government -, and industry - based researchers from the United States and Canada in a combined effort to define the testable prospects
of this novel treatment strategy for HIV - AIDS.
Not exact matches
At a two - day meeting sponsored by the journal Brain Research, The Emerging Neuroscience
of Autism Spectrum Disorders, scientists will discuss how these insights can help trace the disorder's genesis and spur
novel treatment strategies.
But these findings point us to new
strategies and
novel compounds that can be developed as
treatments that will be more effective for an array
of cancer types because they are less susceptible to the emergence
of resistance.»
The concept
of tailoring drugs to regulate and treat abnormal brain blood vessels is a
novel treatment strategy and offers great potential to complement existing
treatments of this debilitating disease.»
«Our approach is likely to «revive» genome - wide association studies as a
strategy to identify genetic risk factors and to develop
novel treatment options for a wide range
of diseases, just as people had hoped for when the genetic code was deciphered a decade ago.»
If we want to change the death rate, we need to increase the investment in understanding the biology
of pancreatic cancer and identifying
novel treatment strategies,» said co-author and pancreatic cancer surgeon Dr. Michael Choti, Chairman
of Surgery, who holds the Hall and Mary Lucile Shannon Distinguished Chair in Surgery.
The study, which is published today in the Journal
of Clinical Hypertension and is supported by Barts Charity, devised a
novel treatment strategy for 55 patients, involving fractional dosing with tablets (halving or quartering pills), liquid formulations
of antihypertensive drugs and patch formulations
of antihypertensive drugs — plus use
of unlicensed drugs that lower blood pressure.
«These results represent a significant advance in our understanding
of how commensal microbes can regulate host intestinal immune responses and suggest that the identification
of downstream targets in macrophages and dendritic cells along the GM - CSF axis can help the rationale design
of novel strategies for the
treatment of IBD patients with defective GM - CSF function,» explained Dr. Merad.
A study led by scientists at The Wistar Institute describes a
novel immunotherapeutic
strategy for the
treatment of cancer based on the use
of synthetic DNA to directly encode protective antibodies against a cancer specific protein.
A gene associated with risk for Alzheimer's disease influences the gut microbiome
of mice, potentiating a
novel treatment strategy (Ishita Parikh, abstract 476.02, see attached summary).
«In reviewing this patient's case, I think we might have found a
novel strategy of using pre-emptive steroids and sirolimus to mitigate organ rejection in transplant patients receiving cancer
treatment involving PD - 1 inhibitors,» said Dr. Jhaveri, associate chief
of the Division
of Kidney Diseases and Hypertension in Northwell Health's Department
of Internal Medicine.
In addition to basic research, Jülich's Institute
of Complex Systems (ICS - 6) is also developing a
novel treatment strategy with its own drug candidate.
This
novel discovery means that scientists can now develop
strategies to target these weak spots for
treatment of dengue, and possibly other closely related diseases like Zika, influenza and chikungunya.
Mohindra, Smita Grade: 7 Home School - Yorktown Heights, NY Project Title:
Novel Strategies in the
Treatment of Vertebrobasilar Insufficiency Using Sensors
In conclusion, the results
of the present study demonstrate the effect
of Hyssopus officinalis L. on chronic asthma, and may provide a
novel therapeutic
strategy for the
treatment of chronic asthma.
Along with our nonprofit partners, this program aims to collect, organize, and validate massive amounts
of data generated by clinical trials across our global trial network sites in order to generate
novel insights into biomarkers for safety and efficacy,
novel treatment strategies, and personalization
of treatment regimens.
Based on our preliminary findings, we propose that our approach may lead not only to a more detailed understanding
of this specific sub-type
of blood cancer, but also to
novel treatment strategies.
The screening proposed here is expected to lead to
novel strategies for the
treatment of centronuclear myopathies by reducing muscle weakness caused by central nuclei in diseased muscles.
We expect the tests developed by the alliance to provide
novel means
of predicting disease risk and
of optimizing disease prevention and
treatment strategies.
One
of its priorities is to develop relevant
strategies to decipher multiple forms
of neuromuscular diseases, identify new therapeutic targets and foster
novel strategies for innovative
treatments.
Dr. Welsbie's laboratory focuses on the development
of neuroprotective agents as a
novel treatment strategy for glaucoma.
Career Goals: Developing
of novel immunotherapeutic
strategies for the
treatment of chronic allergic inflammation and airway remodeling.
This finding reveals unexpected roles for the microbiome and innate immune signalling in the pathogenesis
of a cerebrovascular disease, as well as suggesting
novel strategies for its
treatment.
Clinical trials are central to the development
of novel and life - saving cancer detection, prevention or
treatment strategies.
Kenneth R. Cooke, M.D. University
of Michigan Medical School Acute lung injury after SCT: from laboratory insights to
novel strategies for diagnosis and
treatment
Ann Marie Schmidt, M.D. Columbia University College
of Physicians and Surgeons
Novel therapeutic
strategy for the prevention and
treatment of diabetic complications: antagonism
of receptor for advanced glycation end products
A new study investigates the great potential
of adipose - derived cells as a
novel treatment strategy for the autoimmune neurodegenerative disease Multiple Sclerosis
For patients seeking
treatment for a wide range
of challenging conditions, Partners HealthCare's wealth
of clinical trials offer access to
novel therapies or
treatment strategies otherwise unavailable in the normal course
of care.
The lack
of effective
strategies for ovarian cancer [1] has led to the development
of novel treatment modalities.
The clinical consequences
of the molecular results are discussed in Molecular Tumor Boards for
novel treatment strategies.
It could lead to
novel therapeutic
strategies for the
treatment of anxiety, psychosis, memory, and mood disorders.
This
strategy takes advantage
of the cells «somatic memory
of origin» and
novel reprogramming
strategies to make these cells an effective and safe source
of cells for the
treatment of cartilage defects and osteoarthritis.
In addition, I work closely with colleagues in Lineberger on innovative clinical trials and translational research projects directed at developing
novel strategies for the
treatment of advanced disease.
The concept
of tailoring drugs to regulate and treat abnormal brain blood vessels is a
novel treatment strategy and offers great potential to complement existing
treatments of this debilitating disease,» commented Dr Matthew Campbell, assistant professor in neurovascular genetics at TCD.
Research by Rutgers Cancer Institute
of New Jersey finds that targeting a certain signaling pathway with a diabetes drug may be a
novel prevention and
treatment strategy for pancreatic cancer progression.
The goal
of our research is to provide doctors with key, additional information to choose best
treatment strategies for breast cancers with
novel mutations
of unknown significance.
My interests lie in leveraging the information hidden in large - scale omics data for better understanding
of the mutational processes causing human cancer, for identifying potential cancer prevention
strategies, and for developing
novel approaches for targeted cancer
treatment.
The main focus
of my research program is on design and preclinical evaluation
of novel therapeutic
strategies for
treatment of metastatic cancers, including breast cancer and melanoma.
The endocannabinoid system regulates energy homeostasis through G protein — coupled cannabinoid - 1 receptors5, 6 located in the central nervous system and in various peripheral tissues, including adipose tissue, muscle, the gastrointestinal tract, and the liver.7 While peripheral cannabinoid - 1 receptor activation decreases adiponectin production in adipocytes, 8 central cannabinoid - 1 receptor activation in preclinical studies stimulates eating, decreases muscle, and stimulates hepatic and adipose tissue lipogenic pathways in animal models
of obesity.9 In genetic and diet - induced obesity, rimonabant, a selective cannabinoid - 1 receptor blocker, reduces overactivation
of the central8, 10 and peripheral11, 12 endocannabinoid system8, 10,13 and prevents weight gain and associated metabolic disorders, thus revealing a
novel strategy for the
treatment of obesity and related cardiometabolic disorders.
We hope that finding these genes will point us toward
novel treatment strategies,» said Perlis, who is also an associate professor
of psychiatry at Harvard Medical School.
The final conclusion is that progesterone may ``... provide
novel therapeutic
strategies for the
treatment of sleep disturbances, in particular in the elderly.»
«inhibition
of the gluconeogenic pathway by citrus flavanones, which was similar to that
of the drug metformin, may represent an attractive
novel treatment strategy for type 2 diabetes» [8].
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding
of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation
of new insights into
novel therapies and
treatment strategies.
Researchers will investigate
novel methods
of measuring chronic pain hypersensitivity in cats with osteoarthritis and other degenerative joint diseases to improve diagnostic and
treatment strategies.
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding
of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation
of new insights into
novel therapies and
treatment strategies.
Partner with board - certified specialists in Cornell's neurology services when your patients» lives - and the quality
of their lives; - depend on access to state -
of - the - art technology,
novel treatment strategies, and board - certified specialists who are dedicated to diagnosing, treating, and rehabilitating all categories
of disease involving the central and peripheral nervous systems.
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding
of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation
of new insights into
novel therapies and
treatment strategies.
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding
of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation
of new insights into
novel therapies and
treatment strategies.
Ideally, treating pharmacologists would be blind to concurrent psychosocial
treatments, and the effects
of CFF - CBT or other
novel treatments could be distinguished from the impact
of specific pharmacological agents or dosing
strategies.