Sentences with phrase «of nuclear magnetic resonance spectroscopy»

Not only did he excel in academic work, winning the 2002 Nobel Prize in Chemistry for his advancement of nuclear magnetic resonance spectroscopy, but Wüthrich was also an avid sportsman.

In 1 sentence: PNNL scientists removed a limitation of nuclear magnetic resonance spectroscopy to enable studies never before possible under the extreme conditions found in nature.

The technology brings together the power of nuclear magnetic resonance spectroscopy, which yields a remarkable peek into molecular interactions, and the ability to re-create the extreme conditions found on the tundra, in the deep ocean, or underground — conditions relevant to some of the biggest questions that scientists at DOE laboratories such as PNNL ask.

This was made possible by a combination of nuclear magnetic resonance spectroscopy (NMR) and electron paramagnetic resonance spectroscopy (EPR), two procedures that make it possible to characterise the structural configuration of a protein at atomic resolution.

Not exact matches

Although students at this level learn the basics of techniques such as nuclear magnetic resonance and infrared spectroscopy in school, «they don't have the advantage of using instruments,» Hewson points out.

To map the minute landscape of molecules, at scales as tiny as just tenths of a nanometer, and help decipher their functions, structural biologists have long relied on two tools: nuclear magnetic resonance, or NMR, spectroscopy and X-ray crystallography.

Using a technique called nuclear magnetic resonance spectroscopy, the researchers measured the concentrations of 21 metabolites key to nerve function in the brains of 10 deceased schizophrenia patients and 12 normal human controls.

Why the drug combination works in resistant CML Why such a combination of the two inhibitor types works in an animal model has now been explained by Prof. Stephan Grzesiek's team at the Biozentrum of the University of Basel and Dr. Wolfgang Jahnke from Novartis, by a structural analysis using nuclear magnetic resonance spectroscopy (NMR).

The researchers then used an array of analytical tools — including stool and urine analysis, flow cytometry, light microscopy, nuclear magnetic resonance spectroscopy, and 16S rRNA analysis — to observe the wide - ranging effects of this sequential co-infection.

My particular field of expertise (or more correctly, least incompetence) was investigating interactions of the lithium ion with erythrocytes using nuclear magnetic resonance (NMR) spectroscopy.

«Using advanced nuclear magnetic resonance spectroscopy, we were able to provide an unprecedented view of the internal structure of the protein clumps that form in the disease, which we hope will one day lead to new therapies.»

When Cegelski and her colleagues used a technique called nuclear magnetic resonance spectroscopy to analyze the biofilm around samples of E. coli, the researchers got a surprise.

Using nuclear magnetic resonance spectroscopy, two teams working with the Göttingen - based scientists Markus Zweckstetter and Stefan Becker have now shown the complex three - dimensional structure of the protein «at work» in atomic detail.

In developing this idea, the team clarified the distribution of protons and oxygen vacancies in Sc - doped BaZrO3 by combining nuclear magnetic resonance spectroscopy and thermogravimetric analysis.

We used Fourier - transform ion cyclotron resonance mass spectrometry and nuclear magnetic resonance spectroscopy to show that a sulfilimine bond -LRB-- S = N --RRB- crosslinks hydroxylysine - 211 and methionine - 93 of adjoining protomers, a bond not previously found in biomolecules.

Unfortunately, nature is not always willing to easily part with its secrets, forcing scientists to rely on sophisticated imaging technology — nuclear magnetic resonance (NMR) spectroscopy or mass spectrometry, for example — to decipher the molecular formula of newly discovered organic compounds so they can be replicated in the lab.

With the help of the electrons of the resulting nitrogen vacancy center, even smallest magnetic fields can be detected with a resolution of a few nanometers thanks to nuclear magnetic resonance (NMR) spectroscopy.

LiWang's structural biology lab uses nuclear magnetic resonance (NMR) spectroscopy, the parent technology for MRI, to study the protein structure and dynamics of biological molecules and then uses the structures to gain insights into their function.

Using a variety of methods, including nuclear magnetic resonance spectroscopy, calorimetry and electron microscopy, the researchers evaluated the fibers» structural and mechanical characteristics.

He used infrared spectroscopy to verify the presence of water on precursor lead - oleates, and nuclear magnetic resonance to show that the lead oleate acted as a drying agent, grabbing water out of the solvent.

Unusually for such a project, the TSRI chemists analyzed the 3D atomic structure of their template compound using X-ray crystallography as well as nuclear magnetic resonance spectroscopy.

Determination of structure - substance and substance - receptor relations with nuclear magnetic resonance or x-ray spectroscopy.

It also underscores the utility of solid - state nuclear magnetic resonance (NMR) spectroscopy for imaging the structures of proteins associated with prion diseases.

Investigations of the fibril specimen by solid - state nuclear magnetic resonance spectroscopy provided additional data to build the model and helped to validate the structure.

Researchers characterized the new battery's chemical interactions using a variety of advanced instruments — including nuclear magnetic resonance, Raman spectroscopy, mass spectroscopy and more — at EMSL, the Environmental Molecular Sciences Laboratory, a DOE Office of Science national user facility at PNNL.

To see if their approach worked, the team examined the healed material using nuclear magnetic resonance spectroscopy and other tools at PNNL's Physical Sciences Laboratory along with the helium ion microscope at EMSL, a U.S. Department of Energy Office of Science user facility.

«Probing the molecular architecture of Arabidopsis thaliana secondary cell walls using two - and three - dimensional (13) C solid state nuclear magnetic resonance spectroscopy»

Our experimental and theoretical analysis draws upon nuclear magnetic resonance (NMR) spectroscopy, a variety of microscopy techniques such as transmission electron microscopy, computation tools such as the NWChem for high - performance computational chemistry as well as supercomputers, and other tools.

The stage was set for success, with a dynamic local GPCR community and access to crucial tools of the trade — nuclear magnetic resonance (NMR) spectroscopy and electron microscopy (EM), not to mention the synchrotron in Grenoble.

Once at Yale, he immersed himself in nuclear magnetic resonance (NMR) spectroscopy, to investigate the structure and dynamics of molecules.

Alain Destexhe, Research Director of Unité de Neurosciences CNRS, Gif - sur - Yvette, France Bruno Weber, Professor of Multimodal Experimental Imaging, Universitaet Zuerich, Switzerland Carmen Gruber Traub, Fraunhofer, Germany Costas Kiparissides, Certh, Greece Cyril Poupon, Head of the Nuclear Magnetic Resonance Imaging and Spectroscopy unit of NeuroSpin, University Paris Saclay, Gif - sur - Yvette, France David Boas, Professor of Radiology at Massachusetts General Hospital, Harvard Medical School, University of Pennsylvania Hanchuan Peng, Associate Investigator at Allen Brain Institute, Seattle, US Huib Manswelder, Head of Department of Integrative Neurophysiology Center for Neurogenomics and Cognitive Research, VU University, Amsterdam Jan G. Bjaalie, Head of Neuroinformatics division, Institute of Basic Medical Sciences, University of Oslo, Norway Jean - François Mangin, Research Director Neuroimaging at CEA, Gif - sur - Yvette, France Jordi Mones, Institut de la Macula y la Retina, Barcelona, Spain Jurgen Popp, Scientific Director of the Leibniz Institute of Photonic Technology, Jena, Germany Katharina Zimmermann, Hochshule, Germany Katrin Amunts, Director of the Institute Structural and functional organisation of the brain, Forschungszentrum Juelich, Germany Leslie M. Loew, Professor at University of Connecticut Health Center, Connecticut, US Marc - Oliver Gewaltig, Section Manager of Neurorobotics, Simulation Neuroscience Division - Ecole Polytechnique fédérale de Lausanne (EPFL), Geneve, Switzerland Markus Axer, Head of Fiber architecture group, Institute of Neuroscience and Medicine (INM - 1) at Forschungszentrum Juelich, Germany Mickey Scheinowitz, Head of Regenerative Therapy Department of Biomedical Engineering and Neufeld Cardiac Research Institute, Tel - Aviv University, Israel Pablo Loza, Institute of Photonic Sciences, Castelldefels, Spain Patrick Hof, Mount Sinai Hospital, New York, US Paul Tiesinga, Professor at Faculty of Science, Radboud University, Nijmegen, Netherlands Silvestro Micera, Director of the Translational Neural Engineering (TNE) Laboratory, and Associate Professor at the EPFL School of Engineering and the Centre for Neuroprosthetics Timo Dicksheid, Group Leader of Big Data Analytics, Institute Structural and functional organisation of the brain, Forschungszentrum Juelich, Germany Trygve Leergaard, Professor of Neural Systems, Institute of Basic Medical Sciences, University of Oslo, Norway Viktor Jirsa, Director of the Institute de Neurosciences des Systèmes and Director of Research at the CNRS, Marseille, France

Using nuclear magnetic resonance (NMR) spectroscopy, however, he found at least two different arrangements of the two domains in the protein: one open, one closed, neither resembling that of the crystal structure.

On the other hand, dynamic nuclear polarization of molecules via nitrogen vacancy centers has important applications in nuclear magnetic resonance spectroscopy since it would greatly increase the standard sensitivity of current scanners.

He'd found his way from the University of Utrecht, in the Netherlands, where he'd done his PhD on Nuclear Magnetic Resonance (NMR) spectroscopy, to Uppsala, in Sweden, where as a young post-doc he was learning X-ray crystallography from Alwyn Jones.

Using nuclear magnetic resonance (NMR) spectroscopy, computer simulations and microscopy, the researchers showed how disease mutations and arginine methylation, a functional modification common to a large family of proteins with low - complexity domains, altered the formation of the liquid droplets and their conversion to solid - like states in disease.