Sentences with phrase «of nucleic»

Biochemistry has wide scope and deals with diverse topics, such as molecular genetics, the structure and function of nucleic acids, proteins, and lipids, enzymology, metabolism and bioenergetics, hormones and vitamins and the specialized biochemistry of specific organisms or tissues such as muscle or the brain.
Some inhibit cell wall synthesis while others increase the permeability of cell membranes, activate enzymes that destroy cell walls or interfere with protein synthesis or the metabolism of nucleic acids.
Basically, PCR is a technique that takes a few strands of nucleic acid, generally DNA (sometimes RNA), and multiplies them until there are enough for the analysis.
The blueprint for life is a chain of nucleic acids formed into DNA molecules.
Chlorella has very high levels of nucleic acids (DNA and RNA), which help regulate gene activity, cellular function, detoxification, and is very effective in slowing down the aging process through supporting cellular repair.
Folate, otherwise known as folic acid is part of your B Vitamins and plays a key role in the synthesis of nucleic acid.
It is also good for people with Gilbert's syndrome, an anomaly of liver function, and is required for the synthesis of nucleic acids, collagen, and proteins found in every cell of the body.
Chlorella contains a large number of nucleic acids.
Dr. Maria DeRosa's research examines a type of nucleic acid called «aptamers» that can fold into 3D nanoscale shapes capable of binding tightly to a specific molecular target.
Some bacteria have a loop of DNA, and two interlocking rings of nucleic acid can appear as an intermediate during cell replication.
Total RNA was isolated using the RNeasy Mini Kit from Qiagen and treated with RNase - free DNase I (5 units / 100 µg of nucleic acids, Sigma).
Two Agilent 2100 Bioanalyzers, a Nanodrop spectrophotometer, and an Invitrogen Qubit fluorometer provide quantification and quality assessment of nucleic acids and other samples.
Her doctoral research examined novel separations of nucleic acids using ion - pairing reversed - phase high performance liquid chromatography (IP - RPLC).
Here we present fCCAC, an application of functional canonical correlation analysis to assess covariance of nucleic acid sequencing datasets such as chromatin immunoprecipitation followed by deep sequencing (ChIP - seq).
Nuclear magnetic resonance structure of the nucleic acid - binding domain of severe acute respiratory syndrome coronavirus nonstructural protein 3.
DNA (DeoxyriboNucleic Acid) a molecule composed of two chains of nucleic acid bases held together by hydrogen bonds in a pattern resembling a flexible twisted ladder.
Genetic and genomic analysis of nucleic acids from environmental samples has helped transform our perception of the subsurface as a major reservoir of microbial novelty.
Stepwise synthesis of a nucleic acid to determine nucleotide sequences; inspired the DNA sequencing technique by F.Sanger (Sanger, Nobel Prize Lecture 2004).
Characterization of the nucleic acid binding region of adenovirus DNA binding protein by partial proteolysis and photochemical cross-linking
Schulze - Makuch also noted that a better indicator of life on Mars would be «the presence of DNA, some other nucleic acid or organic macromolecules that could be a breakdown product of a nucleic acid associated with these microfeatures.»
All samples were analyzed for the presence of 18S rRNA to determine the efficiency of the nucleic acid extraction, amplification, and as an indicator of inhibition.
Manuscripts describing BioGPS have been published in the database issues of Nucleic Acid Research in 2016 and 2013, as well as in Genome Biology.
They also identify where chemical modifications of DNA influence gene expression and where various functional forms of RNA, a form of nucleic acid related to DNA, help regulate the whole system.
While there, he worked under Aaron Klug, winner of the Nobel Prize in 1982 for crystallographic electron microscopy and for solving the structures of nucleic acid complexes.
Our research is centered around the Chemical Biology of Nucleic Acids.
A nucleotide is the basic unit of nucleic acid, which is found in the 23 pairs of chromosomes in the human body.
The location and packing density of nucleic acids may control which genetic instructions are accessible and active at any given time.
It was suspected, but not known for certain, that fly as well as mouse Zucchini proteins were nucleases — enzymes that specialize in cleaving bonds between the nucleotide subunits of nucleic acids (DNA and RNA).
«My favorite is the one we cited in the manuscript: «Viruses are entities whose genomes are elements of nucleic acid that replicate inside living cells using the cellular synthetic machinery and causing the synthesis of specialized elements that can transfer the viral genome to other cells.
Leukocyte protease binding to nucleic acids promotes nuclear localization and cleavage of nucleic acid binding proteins.
Over the past decade due to the deep - sequencing technologies, we have studied the characterization of nucleic acid alterations in a wide range of cancers generating a large body of information on how cancer develops and evolves.
«Antisense» compounds are synthesized with nucleotides, the building blocks of nucleic acid, often shown as various combinations of A, U, G and C.
«We are proud to partner with Integrated DNA Technologies, a prominent leader in the field of nucleic acid — based technologies,» said Rachel Haurwitz, Ph.D., President and Chief Executive Officer of Caribou.
For each sample type, a standard curve for the TMAdV PCR assay was calculated from 3 PCR replicates at each dilution of nucleic acid extracted from the spiked matrix (data not shown).
In their report receiving advance online release in Nature, the investigators describe evolved versions of the DNA - cutting Cas9 enzyme that are able to recognize a different range of nucleic acid sequences than is possible with the naturally occurring form of Cas9 that has been used to date.
The result was several series of nucleic acid duplexes that ranged from having all RNA nucleotides to none at all.
«We identified a set of novel microRNAs that are potent inducers of neuroblastoma cell differentiation and found that mimics (synthetic fragments of nucleic acid used to raise microRNA levels in cells) of some of the identified microRNAs are much more potent in inducing neuroblastoma cell differentiation than the current differentiation treatments.
Bacterial microbes face a never - ending onslaught from viruses and invasive snippets of nucleic acid known as plasmids.
It is a member of an understudied class of nucleic acids that biologists call long non-coding RNAs (lncRNAs).
So that made us look again at the chemistry of replication and start to explore a wider range of nucleic acids.
Investigations of how short chains of nucleic acids replicate themselves in vitro have even provided clues to primitive genetic codes for translating nucleic acid information into protein information, systems that could have preceded the elaborate machinery of ribosomes and activating enzymes with which cells now manufacture protein.
With his wife, Margaret, Clark then moved to Boston, where he had secured a 3 - year postdoc with Jack Buchanan, a biochemist at the nearby Massachusetts Institute of Technology (MIT) who was investigating the synthesis of nucleic - acid building blocks called purines and of proteins.
ANA (amyloid nucleic acid) consists of nucleic acids attached to amyloid proteins, infamous for their role in Alzheimer's disease.
Joint winners of the 1962 physiology or medicine prize with Maurice Wilkins «for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material.»
«Successful detection of nucleic acids in Martian permafrost samples would provide unambiguous evidence of life on another world,» says Dr Goordial.
The technique introduces modified segments of nucleic acid from the gene that produces the nicotine demethylase enzyme.
BioGene is at the forefront of innovative, UltraRapid Molecular Biology solutions for rapid detection of nucleic acids and this research has led to a very exciting platform technology, and one that we are looking to develop further.»
MicroRNAs are very short bits of nucleic acid — the material of DNA and RNA — that can bind to messenger RNAs that code for protein.
MicroRNAs are short bits of nucleic acid — the material of DNA and RNA — that can bind to messenger RNAs that code for protein because they have a complementary sequence of A, U, C and G.
Department of Nucleic Acids Research, Genetic Engineering and Biotechnology Research Institute, City for Scientific Research and Technology Applications, Borg El - Arab, Post Office Box 21934, Alexandria, Egypt.
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