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One
of my nulliparous patients was a professional landscaper who had engaged in a long and successful career.
Variation in the rates
of nulliparous term singleton vertex cesarean births indicates that clinical practice patterns affect the number of cesarean births performed.
The percentage of women with a non-Dutch background was also small in our study population: 3.1 % in total, as compared with 25.3 %
of all nulliparous women in the Netherlands in 2012 [19].
The rates of assisted vaginal births and cesarean sections in this study are comparable to the national data
of nulliparous women from 2012 (16.4 % assisted vaginal birth and 17.7 % caesarean section)[19].
Not exact matches
: «1.1.1 Explain to both multiparous and
nulliparous women who are at low risk
of complications that giving birth is generally very safe for both the woman and her baby.
Advise low ‑ risk
nulliparous women that planning to give birth in a midwifery ‑ led unit (freestanding or alongside) is particularly suitable for them because the rate
of interventions is lower and the outcome for the baby is no different compared with an obstetric unit.
1.1.2 Explain to both multiparous and
nulliparous women that they may choose any birth setting (home, freestanding midwifery unit, alongside midwifery unit or obstetric unit), and support them in their choice
of setting wherever they choose to give birth: Advise low ‑ risk multiparous women that planning to give birth at home or in a midwifery ‑ led unit (freestanding or alongside) is particularly suitable for them because the rate
of interventions is lower and the outcome for the baby is no different compared with an obstetric unit.
In other words, there was no difference in severe acute maternal morbidity (SAMM) between home and hospital among
nulliparous women and a slightly lower rate
of SAMM for parous women at homebirth.
This is based on the number
of women who fall into a category called NTSV (
nulliparous term singleton vertex), or first time mothers at term, with one head down baby.
For healthy
nulliparous women with a low risk pregnancy, the risk
of an adverse perinatal outcome seems to be higher for planned births at home, and the intrapartum transfer rate is high in all settings other than an obstetric unit
Our results support a policy
of offering healthy
nulliparous and multiparous women with low risk pregnancies a choice
of birth setting.
«Women with planned home birth had lower rates
of all adverse maternal outcomes, albeit not significantly so for
nulliparous women.»
In the subgroup analysis stratified by parity, there was an increased incidence
of the primary outcome for
nulliparous women in the planned home birth group (weighted incidence 9.3 per 1000 births, 95 % confidence interval 6.5 to 13.1) compared with the obstetric unit group (weighted incidence 5.3, 3.9 to 7.3).
For
nulliparous women the rate for planned home versus planned hospital birth was 2.3 versus 3.1 per 1000 births (adjusted odds ratio 0.77, 95 % confidence interval 0.56 to 1.06), relative risk reduction 25.7 % (95 % confidence interval − 0.1 % to 53.5 %), the rate
of postpartum haemorrhage was 43.1 versus 43.3 (0.92, 0.85 to 1.00 and 0.5 %, − 6.8 % to 7.9 %), and the rate
of manual removal
of placenta was 29.0 versus 29.8 (0.91, 0.83 to 1.00 and 2.8 %, − 6.1 % to 11.8 %).
For
nulliparous women, there is some evidence that planning birth at home is associated with a higher risk
of an adverse perinatal outcome.
When the analysis was restricted to units or trusts with a response rate
of at least 85 %, the higher odds
of the primary outcome for
nulliparous women in the planned home birth group remained, and the strength
of this association increased (appendix 5 on bmj.com).
However, higher rates
of a composite outcome
of perinatal morbidity and mortality were seen for
nulliparous women having homebirths (adjusted odds ratio 1.75; 95 % CI, 1.07 — 2.86), with no differences for multiparous women.
J. A. Thorp et al., «The Effect
of Continuous Epidural Analgesia on Cesarean Section for Dystocia in
Nulliparous Women,» Am J Obstet Gynecol 161, no. 3 (1989): 670 — 675.
The odds
of cesarean section among women planning out -
of - hospital birth were lower among multiparous women than among
nulliparous women and among women with 12 years
of education or less than among women with more than 12 years
of education (Figure 1).
We therefore assigned
nulliparous women the same risk
of metabolic disease as women who breastfed for 6 or more months.
We used multivariable logistic - regression models to adjust for potential confounders, including maternal race or ethnic group (non-Hispanic white vs. other), parity (
nulliparous vs. multiparous), insurance status (public or none vs. other), extent
of prenatal care (≥ 5 visits vs. < 5 visits), advanced maternal age (≥ 35 years vs. < 35 years), maternal education (> 12 years vs. ≤ 12 years), history or no history
of cesarean delivery, and a composite marker
of conditions that confer increased medical risk.
Characteristics
of low - risk
nulliparous women who initially preferred a midwife - led home or hospital birth or an obstetrician - led birth
There was, however, an increased incidence
of adverse perinatal outcome associated with planned birth at home in
nulliparous low risk women, resulting in the probability
of it being the most cost effective option at a cost effectiveness threshold
of # 20000 declining to 0.63.
Nice post I found something similar to Clara finding: «The Effect
of Late Pregnancy Consumption
of Date Fruit on Cervical Ripening in
Nulliparous Women» (https://www.ncbi.nlm.nih.gov/pubmed/21280989).
There was, however, an increased incidence
of adverse perinatal outcomes associated with planned birth at home in
nulliparous low risk women, resulting in the probability
of it being the most cost effective option at a threshold
of # 20000 declining to 0.63.
This cost effectiveness information, however, should be considered in the light
of an increased risk
of adverse perinatal outcome associated with planned home birth in low risk
nulliparous women.
Fig 2 Cost effectiveness plane: planned birth at home compared with planned birth in obstetric units for
nulliparous low risk women without complicating conditions at start
of care in labour
With regards to maternal outcomes in
nulliparous and multiparous women, planned birth at home generated the greatest mean net benefit with a 100 % probability
of being the optimal setting across all thresholds
of cost effectiveness.
Parsons Bidewell, and Nagy (2006) studied the effect
of eating in early labor on maternal and infant outcomes in a prospective comparative trial
of 176 low - risk
nulliparous Australian women.
The rates
of NICU admissions and low Apgar scores did not significantly differ among
nulliparous women (NICU admissions up to 28 days, 3.41 % versus 3.61 %, aOR 1.05, 95 % CI: 0.92 to 1.18).
The combined intra-partum and neonatal death rates up to 28 days after birth, including cases with discrepancies in the registration
of the moment
of death, were: for
nulliparous women, 1.02 % for planned home births versus 1.09 % for planned hospital births, adjusted OR (aOR) 0.99, 95 % CI: 0.79 to 1.24; and for parous women, 0.59 % versus 0.58 %, aOR 1.16, 95 % CI: 0.87 to 1.55.
In a secondary analysis
of a multicenter randomized study
of fetal pulse oximetry,
of 4,126
nulliparous women who reached the second stage
of labor, none
of the following neonatal outcomes was found to be related to the duration
of the second stage, which in some cases was 5 hours or more: 5 - minute Apgar score
of less than 4, umbilical artery pH less than 7.0, intubation in the delivery room, need for admission to the neonatal intensive care unit, or neonatal sepsis (27).
Given the available literature, before diagnosing arrest
of labor in the second stage and if the maternal and fetal conditions permit, at least 2 hours
of pushing in multiparous women and at least 3 hours
of pushing in
nulliparous women should be allowed (Table 3).
In the era
of electronic fetal monitoring, among neonates born to
nulliparous women, adverse neonatal outcomes generally have not been associated with the duration
of the second stage
of labor.
For example, the recent Eunice Kennedy Shriver National Institute
of Child Health and Human Development document suggested allowing one additional hour in the setting
of an epidural, thus, at least 3 hours in multiparous women and 4 hours in
nulliparous women be used to diagnose second - stage arrest, although that document did not clarify between pushing time or total second stage (33).
In this study, the 95th percentile rate
of active phase dilation was substantially slower than the standard rate derived from Friedman's work, varying from 0.5 cm / h to 0.7 cm / h for
nulliparous women and from 0.5 cm / h to 1.3 cm / h for multiparous women (the ranges reflect that at more advanced dilation, labor proceeded more quickly)(Table 2).
In
nulliparous women, a period
of 8 hours
of augmentation resulted in an 18 % cesarean delivery rate and no cases
of birth injury or asphyxia, whereas if the period
of augmentation had been limited to 4 hours, the cesarean delivery rate would have been twice as high given the number
of women who had not made significant progress at 4 hours.
A prospective study
of the progress
of labor in 220
nulliparous women and 99 multiparous women who spontaneously entered labor evaluated the benefit
of prolonging oxytocin augmentation for an additional 4 hours (for a total
of 8 hours) in patients who were dilated at least 3 cm and had unsatisfactory progress (either protraction or arrest) after an initial 4 - hour augmentation period (21).
Women were defined by sociodemographic criteria in three studies: living in the three most disadvantaged postcode areas and over the age
of 16 (Hoddinott 2012), over 18,
nulliparous, low income families, who had not yet selected a paediatrician (Serwint 1996), and low - income urban women (Sellen 2013).
The vaginal delivery rate for women who had not progressed despite 2 hours
of oxytocin augmentation was 91 % for multiparous women and 74 % for
nulliparous women.
Researchers have found that after a 3 - hour or more second stage
of labor, only one in four
nulliparous women (27) and one in three multiparous women give birth spontaneously, whereas up to 30 — 50 % may require operative delivery to give birth vaginally in the current second stage
of labor threshold environment (30).
Objective: To compare the efficacy
of oral misoprostol to vaginal dinoprostone for labor induction in
nulliparous women.Study design: Admissions for labor induction from January 2008 to December 2010 were reviewed.
On the basis
of the 95th percentile threshold, historically, the latent phase has been defined as prolonged when it exceeds 20 hours in
nulliparous women and 14 hours in multiparous women (18).
This also was found in a large, retrospective cohort study
of 15,759
nulliparous women even in a group
of women whose second stage progressed beyond 4 hours (29).
The incidence
of PPH for planned hospital births would be expected to be higher than the incidence for planned home births, because
nulliparous women are more likely to experience PPH (see Table 2), and are also more likely to plan a hospital birth [28].
The researchers recommend that «
Nulliparous [first baby] women should be made aware
of this, as well as potential risks
of expectant management during counselling.»
In fact, the absolute risk risk
of birth - related perinatal death associated with VBAC is extremely low and comparable to the risk for
nulliparous women in labor.
Dr. Lowe's primary research foci are (a) biobehavioral aspects
of the childbearing experience and its processes, (b) care during labor, and (c) postpartum outcomes
of healthy,
nulliparous women.
Haugen, M., Brantsaeter, A. L., Trogstad, L., Alexander, J., Roth, C., Magnus, P., and Meltzer, H. M. Vitamin D supplementation and reduced risk
of preeclampsia in
nulliparous women.