Sentences with phrase «of obese human»

We found that if C. minuta was added to the feces of an obese human donor, the recipient mice were thinner than when C. minuta was not added.

The only grave goods with these Tarxien people (which have been dated by the radiocarbon method to around 2800 B.C.E.) were small, carefully modeled ceramic statuettes of obese human figures.

But when injected into hundreds of obese human volunteers, leptin's effect was clinically insignificant.

Those temples and the underground burial chambers related to them contained many images of obese humans — some no larger than a few centimeters, others the size of giants — as well as of animals and phallic symbols.

But this goes beyond just rodents... they have also shown that there is probably also low - level inflammation occurring in the brains of obese humans (6).

Not exact matches

We have a choice: agonize over the lost of an energy obese society or embrace a low energy, subsistence lifestyle that has worked for most of humans over the centuries.

Researchers theorized that something similar might be going on in obese humans, but when they began taking blood samples, they found that obese people show very high levels of leptin.

The large amounts of fat around the testes of obese mice, «could alter the environment and encourage epigenetic changes», says Teague, who presented the results at the 14th World Congress on Human Reproduction in Melbourne, Australia, this month.

The level of POPs needed to have an adverse affect in humans is unknown, so it should not stop obese people trying to lose weight, says Amanda Sainsbury - Salis at the Garvan Institute of Medical Research in Sydney, Australia.

The scientists are now expanding their research to larger numbers of animals and they are also planning a study to look at addiction - like behaviours in obese people to see how well their results translate to humans.

A common antioxidant found in human breast milk and foods like kiwi fruit can protect against nonalcoholic fatty liver disease (NAFLD) in the offspring of obese mice, according to researchers at the University of Colorado Anschutz Medical Campus.

«Our knowledge gained from penguins provides novel insight into the gait mechanics of humans with increased lateral movements, such as in pregnant women or obese individuals,» he says.

«Perhaps supplementing the diet of obese pregnant mothers with PQQ, which has proven safe in several human studies, will be a therapeutic target worthy of more study in the battle to reduce the risk of NAFLD in babies,» Jonscher said.

In humans, as in mice, fat cells of the obese already produced plenty of leptin — more in fact than those of their thin counterparts, since the level of leptin was directly proportional to the amount of fat.

In the human abdominal adipose (fat) tissue of lean individuals, the amounts of Pellino3 are high, but in adipose tissue from obese individuals the levels of Pellino3 fall.

In both human and laboratory studies, the offspring of mothers who are obese or consume a high - fat diet during pregnancy are much more likely to be overweight and have weight - related problems such as metabolic syndrome, diabetes and heart disease later in life.

To explore the relevance of these results to humans, the TSRI team worked with collaborating researchers in Australia to test fat samples from obese humans and diabetics.

To determine how the drug works in the human brain, Mantzoros and colleagues observed 48 obese men and women — half taking the drug, half taking a placebo — over the course of a four - week experiment.

In previous studies, Chong Wee Liew, assistant professor of physiology and biophysics in the UIC College of Medicine, and his colleagues found that in obese humans TRIP - Br2 was turned - up in visceral fat but not in subcutaneous fat.

Given that adipose tissue (which makes up between 15 and 20 % of the body weight in healthy people) is a source of inflammation in obese individuals, Christine Bourgeois and Olivier Lambotte, from the University Paris SUD, France, and colleagues, decided to investigate a possible role of the adipose tissue in humans infected with HIV and in macaques infected with simian immunodeficiency virus (SIV, an HIV relative that causes AIDS - like disease in some non-human primates).

When the Cornell team cultured human breast cancer cells on matrix deposited by fat - derived cells from obese mice, the cancer cells grew faster than they did on the matrix of cells from slimmer mice.

Based on the observation that obese mice, rats, and humans all had elevated serum concentrations of a protein called GDF15 compared to lean controls, Yumei Xiong and colleagues set out to develop therapies derived from the molecule.

Cytos, a biotechnology company outside of Zurich, Switzerland, is testing a different antighrelin vaccine in a clinical trial of 112 obese humans; results, says Martin Bachmann, Cytos's chief scientific officer, will be available in November.

Skeletal muscle tissue also produces increased amounts of iNOS and TNF - α in obese compared with lean rodents and humans (21, 71).

We estimate that the percentage of macrophages in adipose tissue ranges from under 10 % in lean mice and humans to over 50 % in extremely obese, leptin - deficient mice and nearly 40 % in obese humans.

The researchers concluded that WBV can mimic the benefits of exercising regularly for muscle and bone health, and could potentially help morbidly obese humans» metabolism.

Also in humans who are obese and diabetic, appear to have high expression of PTP1B.

Symposia VI: Cardiovascular Benefits of Exercise: Insights from Human Studies The session will cover improving exercise tolerance in heart failure, reversal of impaired cardiac function in obese adolescents, the effect of exercise on left ventricular compliance and diastolic function in the elderly and attenuating premature cardiovascular aging in Type 2 diabetes through exercise.

«From other research, a Mediterranean - style diet, richer in MUFA (from olive or rapeseed oils) and other unsaturated oils at the expense of saturated fats, appears protective of heart disease and cancer in humans — even in overweight (but not obese) subjects.

Both obese humans and mice have significantly elevated soluble Fabp4 / aP2 levels, and injection of recombinant Fabp4 / aP2 into lean wild type mice stimulates hepatic glucose production and gluconeogenesis.

In one recent study, obese rats that ate the human equivalent of two cups of wild blueberries per day for eight weeks experienced a significantly improved inflammatory response.

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«National Survey data shows that the prevalence of overweight and obese adults in the U.S. has increased steadily over the past three decades», said Youfa Wang, MD, PhD, lead author of the study and associate professors with the Bloomberg School's Center for Human Nutrition.

Researchers from the University of Alabama at Birmingham found that obese rats fed a high - fat, low - carb diet — comparable to what many humans consume — had more damaging and deadly heart attacks than obese rats fed a low - fat diet.

Humans: Trials Using the Intermittent Very Low Energy Approach: In overweight and / or obese populations, the majority of IER (60 - 85 % ER / alternate days) trials spanning four to 12 weeks have consistently demonstrated global improvements in cardiovascular risk markers, encompassing enhancements in glucose metabolism (described above) and lipid profiles 37 - 40, 42, 46, 49, 50 - 52 relative to baseline, which collectively would be expected to improve vascular function.

Now please think of the last time you went to a mall: what percentage of the humans you saw there were overweight or obese?

Leptin levels in human and rodent: measurement of plasma leptin and ob NAN in obese and weight - reduced subjects.

The great news is that by adding fermented veggies into your foods, you are changing your gut health for better: «the composition of the gut microbiota has been shown to differ in lean and obese humans and animals and to change rapidly in response to dietary factors.

Altering the gut genome from obese to lean has «long lasting effects» when combined with a «healthy diet high in fiber and low in saturated fats,» confirming multiple studies that show «that the food we eat has a direct relationship to the types of bacteria produced in the human digestive system;»

BMI is the measure of body fat, based on height and weight of humans of 18 - 65 years, which depending on the results may indicate if the person is overweight, obese, underweight or normal.

The U.S. Department of Health and Human Services reports that overweight and obese men often have weight loss success when following 1,200 - to 1,600 - calorie meal plans.

In the human study, obese people who lost weight increased their bacteroidetes, while the numbers of firmicutes decreased.

Two studies supporting this theory — one looking at mice, the other using humans — found that a family of bacteria known as firmicutes was more plentiful in the obese (20 percent more), whereas another bacteria called bacteroidetes was almost 90 percent lower in obese subjects.

In obese humans, substitution of carbohydrate with protein leads to far greater weight loss, nearly twice as much.

Intriguing new research has indeed shown that it's possible human metabolic rates are more evolutionary in origin than a reflection of our modern lifestyles — confirming that what you choose to eat could be the most important factor in your risk of becoming overweight or obese.

On the other hand, if you have lower human growth hormone levels than normal as a result of the normal aging process, you can become obese and be unable to burn off that excess fat and restore your muscle tone.

In rodents, ketogenic diets reduce reactive oxygen species in the brain34 and reduce central inflammation and reactive oxygen species in a model of multiple sclerosis.35 Two clinical papers have found that ketogenic diet feeding of 12 weeks to 6 months reduced signs of liver inflammation in obese patients with nonalcoholic fatty liver disease (in addition to improving various other physiological and biochemical variables).36, 37 Unfortunately, basic research into non-alcoholic fatty liver disease has been hampered by species differences between mice and humans in their hepatic reaction to ketogenic diets.38

In both animal and human studies, it has been shown that an obese person's (or animal's) microbiome allows for increased energy harvesting, or the extraction of more calories from the diet.

Green coffee bean extract (GCBE) also contains chlorogenic acids, and a recent study found that GCBE supplementation reduced body fat and resting heart rate in obese human subjects, though researchers weren't sure whether the caffeine content of GCBE was partly responsible.»

Because humans obtain most of their vitamin D requirement from casual exposure to sunlight, the > 50 % decreased bioavailability of cutaneously synthesized vitamin D3 in the obese subjects could account for the consistent observation by us and others that obesity is associated with vitamin D deficiency.