Despite increased understanding
of heart disease risk factors and the need for preventive lifestyle changes,
patients suffering the most severe type
of heart attack have become younger, more
obese and more likely to have preventable risk factors such as smoking, high blood pressure, diabetes and chronic obstructive pulmonary disease, according to a study scheduled for presentation at the American College
of Cardiology's 65th Annual Scientific Session.
The treated rodents were not only fatter but also
suffered elevated levels
of fasting insulin, and alterations in genes related to liver regeneration and detoxification — effects consistent with metabolic disorders in
obese patients.