Metabolic responses
of obese subjects to starvation and low - calorie ketogenic and nonketogenic diets
A study in the journal Obesity Research examined the effects of differing calcium intakes in three groups
of obese subjects placed on calorie - restricted diets.
Inaccuracies in food and physical activity diaries
of obese subjects: complementary evidence from doubly labeled water and co-twin assessments.
Cortisol, obesity and the metabolic syndrome: A cross-sectional study
of obese subjects and review of the literature.
As you can see, both groups
of obese subjects had higher levels of insulin secretion compared to the non-obese.
In a study of more than 14,000 metabolically healthy Korean people last year, scientists found early plaque buildup in the arteries
of obese subjects more often than they did in the lean ones.
Not exact matches
In one study out
of the University
of Tennessee, researchers showed that eating three servings
of dairy daily significantly reduced body fat in
obese subjects.
The scientists investigated whether this change in PPAT was responsible for the aggressiveness
of prostate cancer in
obese subjects.
Diabetes: A Nurses» Health Study
of 114,000 women found the risk
of getting diabetes was 93 times as high in
obese subjects.
And the original
subjects were 20 percent more likely than that to be
obese if a friend
of a friend became
obese — even if the person connecting the two stayed slender.
In a study
of 45 overweight or
obese subjects who ate a moderate - fat diet including an avocado daily had lower bad cholesterol than those on a similar diet without the avocado or those on a lower - fat diet (American Heart Association, 2015).
Bartoshuk was surprised to find that
subjects with a history
of moderate to severe middle - ear infections were 62 percent more likely than the others to be
obese, according to data presented at the American Psychological Association meeting in August.
Based on the emerging evidence for the existence
of the very interesting extreme metabolic phenotypes metabolically healthy obesity and metabolically unhealthy normal weight the scientist then studied the prevalence
of the 4 at - risk phenotypes among the different BMI categories (normal weight, overweight, and
obese) in
subjects with NGR and prediabetes.
The MRI scans showed that
obese subjects with binge eating disorder have lower grey matter volumes — a measure
of the number
of neurons — in the orbitofrontal cortex and striatum
of the brain compared to those who do not binge eat; these brain regions are involved in keeping track
of goals and rewards.
The Inventory
of Nocturnal Eating, a self - report questionnaire addressing nocturnal eating and sleep disturbance, was administered to out - patients (N = 126) and in - patients (N = 24) with eating disorders,
obese subjects (N = 126) in a trial
of an anorexic agent, depressed
subjects (N = 207) in an antidepressant trial, and an unselected group (N = 217)
of college students.
The
subjects weren't
obese initially, and none gained a significant amount
of weight during the study.
Healthy lean, overweight, and
obese subjects were admitted to the Clinical Research Center at Columbia Presbyterian Medical Center (New York, New York, USA) as part
of a longitudinal study
of the metabolic effects
of weight perturbation.
Among younger normal - weight sedentary volunteers (217) and also in
obese and diabetic
subjects (218), females had higher IMCL in leg muscle (219), higher lipid area density, and greater number
of IMCL droplets than males.
However, in
obese diabetic
subjects, insulin stimulates the FV
of GS to a lower extent (6).
Since the unrelated NGT
subjects have a broad BMI range, we further examined the impact
of obesity on the expression
of these six genes by comparing nonobese and
obese NGT
subjects.
E: Comparison
of mRNA expression levels in adipose tissue from nonobese (BMI < 30 kg / m2, n = 40) and
obese (BMI > 30 kg / m2, n = 30) NGT
subjects.
More than half
of the investigated sexually active
obese diabetic women and men complained about sexual dysfunction, which is much higher than in healthy lean
subjects (342, 343).
In this study, we compared a group
of «supernormal» young lean
subjects with the most common form
of type 2 diabetes in
obese elderly diabetic
subjects in order to optimize our conditions for finding significant differences.
«From other research, a Mediterranean - style diet, richer in MUFA (from olive or rapeseed oils) and other unsaturated oils at the expense
of saturated fats, appears protective
of heart disease and cancer in humans — even in overweight (but not
obese)
subjects.
It also synced with production
of beige fat in
obese diabetic
subjects.
This trial targeted
obese people in Louisiana, but since the previous study for low - carb diets had included a very low number
of people
of color, this trial was made much more representative, with over 50 %
of the
subjects being people
of color.
In one study consisting
of approximately 20,000
subjects, scientists found that both men and women were around 1.5 times more likely to have excess weight or be
obese if they ate 5 or more times a day, compared to 3 times or fewer.
In a study
of 32
obese subjects with insulin resistance, a blueberry smoothie caused major improvements in insulin sensitivity (30).
Comparison
of 5 % versus 15 % sucrose intakes as part
of a eucaloric diet in overweight and
obese subjects: effects on insulin sensitivity, glucose metabolism, vascular compliance, body composition and lipid profile.
Within diabetic populations, hyperglycaemia is considered the hallmark diagnostic marker
of metabolic abnormality and a major contributor to T2DM associated macro - and micro - vascular complications.61 One study by Ash et al 36 saw 51 overweight /
obese male
subjects with T2DM assigned to one
of three groups; (i) IER (four days 50 % ER, three days ad libitum intake / week), (ii) CER (30 % ER / day, all meals provided) and (iii) CER (30 % ER / day, food self - selected by the participant).
Another article in 2006 showed that there was an overall decrease in body weight, total cholesterol, LDL, triglycerides, and blood glucose with an increase in HDL for
obese subjects with either a known history
of high cholesterol or normal cholesterol.
In overweight or
obese subjects, IER (60 - 85 % ER / alternate days) have been shown to produce an average weight loss
of between -5 and -8 % body - weight in studies
of four to 12 weeks duration with the degree
of weight - loss seemingly correlated to the length
of the intervention.37, 38, 40, 45 - 47, 49 - 52 Weight - loss is accompanied by reductions in whole - body adiposity 37, 38, 40, 45 - 47, 49 - 52, waist circumference39, 40, 43, 45 and favourable shifts in adipokine expression encompassing lowered circulating levels
of TNF - a 37, IL - 6 37, resistin 39, 49 and augmented adiponectin expression 39, consistent with favourable modulations in adipose function.
Conversely ghrelin, produced mainly by P / D1 cells lining the fundus
of the stomach, exerts appetite stimulating effects and so levels are typically at their peak pre-meal and decrease post - prandially.87 As weight - loss is associated with increased fasting levels
of ghrelin 88 and reduced suppression in response to a meal in
obese subjects 89, changes in circulating ghrelin levels have been assessed in several IER studies.
One study showed that
obese individuals had 57 % lower levels
of vitamin D following UV exposure compared to non-
obese subjects [2].
In this [pioneering] study,
obese patients were
subjected to a variety
of performance assessments in a baseline period, then after 1 and 6 weeks
of weight loss via protein - sparing modified fast (1.2 g / kg ideal body weight from lean meat, fish, or fowl; probably around 80 grams
of protein / d, 500 - 750 kcal / d).
Low levels
of physical activity in
obese subjects are a better predictor
of death than cholesterol levels, smoking status or blood pressure.
Lean
subjects had a mean TDEE
of 2404 calories while the
obese had a mean TDEE
of 3244 calories.
What nobody mentions is that the
subjects of this study were grossly
obese, with BMIs over 40.
We also showed that both FO supplementation and regular moderate exercise reduced body fat in overweight or
obese subjects who were at risk
of CVD.
A handful
of studies exist showing an insulin response from just sweet taste in healthy people, and some studies show a lot
of variation in
obese subjects, as well.
The majority
of subjects in both studies were overweight and
obese.8 Obesity is associated with increased sodium excretion and with increased cardiovascular risk.
Higher activation
of this brain region has been found in
obese compared with normal - weight
subjects when anticipating food, suggesting that the rewarding quality
of food is enhanced in obesity.
Recent studies that used the conventional blood oxygenation level — dependent fMRI have shown selective overactivity in the nucleus accumbens and related brain areas in
obese compared with lean individuals when shown imagines
of highly palatable food (6 — 11) and in
subjects who scored high on a measure
of food addiction (39).
Secondly, bitter taste stimulates the secretion
of polypeptide YY (PYY), which reduces food intake in
subjects of normal weight, so researchers decided to test the effects
of the peptide infusion on the appetites
of 12
obese and 12 lean
subjects in a double - blind, placebo - controlled crossover study.
Beneficial effects
of apple cider vinegar on weight management, visceral adiposity index and lipid profile in overweight or
obese subjects receiving restricted calorie diet: A randomized clinical trial.
Leptin levels in human and rodent: measurement
of plasma leptin and ob NAN in
obese and weight - reduced
subjects.
Two studies supporting this theory — one looking at mice, the other using humans — found that a family
of bacteria known as firmicutes was more plentiful in the
obese (20 percent more), whereas another bacteria called bacteroidetes was almost 90 percent lower in
obese subjects.
Sixty - two percent
of the
subjects were overweight or
obese and had an average BMI
of 27.2.
Randomized, multi-center trial
of two hypo - energetic diets in
obese subjects:.
In these 2 studies, 6
obese, untrained
subjects and 5 highly trained bicycle racers were tested for fitness and endurance at baseline, and then given 1.2 to 1.75 g
of protein per kg
of reference weight for 4 - 6 weeks
of a ketogenic diet.