CCC's journals cover a wide range of current research serving the fields
of oncology research, gene expression & therapy, pain research, cell transplantation, alternative medicine, and technology.
Rutgers Cancer Institute of New Jersey has partnered with top cancer centers across the nation to become a member
of the Oncology Research Information Exchange Network (ORIEN).
This webinar will discuss the differences between these two types of lab animal diets and how they can affect different aspects
of oncology research in rodents.
Prof. Richard Sullivan, director of the Institute of Cancer Policy, King's Health Partners Comprehensive Cancer Centre, King's College London, and co-author of the Annals
of Oncology research paper.
Dr. Bolen, the chief scientific officer and global head
of oncology research at Millennium: The Takeda Oncology Company has served in senior leadership positions at Millennium since 1999.
PDX models are created by implanting cancerous tissue from a human primary tumor directly into immunodeficient mouse or rat models, enabling acceleration
of oncology research or drug discovery and development programs.
Immunotherapy has been emerging from the backdrop
of oncology research for years most notably from smaller companies such as Dendreon, Kite Pharma and Juno Therapeutics as leaders in the space.
To get a sense of what that process is like, at least at one major pharmaceutical company, we turned to Bob Abraham, Pfizer's head
of oncology research and development.
Not exact matches
In a statement released Tuesday, the American Society
of Clinical
Oncology outlined
research tying alcohol to two types
of cancer and told Americans to drink less.
This has also made it one
of the most highly
researched — approximately 50,000
oncology research papers are published annually, according to PubMed data cited by Elekta.
Participants included CEOs Jonathan Bush
of Athenahealth, Ron Gutman
of HealthTap, Dr. Clifford Hudis
of the American Society
of Clinical
Oncology, Dr. Vivian Lee
of University
of Utah Health Care, VitalConnect CEO Nersi Nazari, James Park
of Fitbit, and Andrew Witty
of GSK, as well as President
of Flex Health Solutions John Carlson, Multiple Myeloma
Research Foundation Founder Kathy Giusti, Dr. Sanjay Gupta, Arianna Huffington, Andreessen Horowitz General Partner Vijay Pande, Parker Foundation President Sean Parker, Women's Alzheimer's Movement Founder Maria Shriver, and White House Cancer Moonshot Task Force Executive Director Greg Simon.
He also served as Global Head
of the Immuno -
Oncology Translational Innovation Platform where he was instrumental in rebuilding immuno - oncology (IO) research at the company, including pruning and re-orienting the discovery p
Oncology Translational Innovation Platform where he was instrumental in rebuilding immuno -
oncology (IO) research at the company, including pruning and re-orienting the discovery p
oncology (IO)
research at the company, including pruning and re-orienting the discovery pipeline.
While Canadian biotechnology expatriates are the focus
of this initiative, FACIT continues to attract worldwide leaders in
oncology research to the province, a shared mandate well established by its strategic partner, the Ontario Institute for Cancer Research
research to the province, a shared mandate well established by its strategic partner, the Ontario Institute for Cancer
ResearchResearch (OICR).
Dr. Larry Garbo and RN Amy Zuchelkowski
of New York
Oncology Hematology join Medical Monday to discuss clinical
research.
«Our study suggests that epigenetic changes to cells treated with cigarette smoke sensitize airway cells to genetic mutations known to cause lung cancers,» says Stephen Baylin, M.D., the Virginia and D.K. Ludwig Professor for Cancer
Research and professor
of oncology at the Johns Hopkins Kimmel Cancer Center.
«We're trying to build models that describe how tumors grow and respond to therapy,» said Yankeelov, director
of the Center for Computational
Oncology at The University
of Texas at Austin (UT Austin) and director
of Cancer Imaging
Research in the LIVESTRONG Cancer Institutes
of the Dell Medical School.
His interest in
research grew while he did his medical degree at Stanford, so he enrolled in Stanford's
research - residency program, which allowed him to do 2 years
of traditional residency training with a 3rd - year
research fellowship in hematology -
oncology.
Hearing about the lipid biochemistry
research from the Babraham Institute team and realising how we could translate its potential from an
oncology perspective was a great moment for all
of us!»
TCGA data, which has been the foundation
of many immuno -
oncology hypotheses and discoveries, will still be available for
research.
We have estimated that up to 15 percent
of patients will be candidates for dose optimization,» explained senior study author Javier F.Torres - Roca, MD, director
of Clinical
Research and associate member
of the Department
of Radiation
Oncology at Moffitt.
Publishing April 4 in the Journal
of Clinical
Oncology, the
research team compared the shortened radiation therapy schedule
of about 5.5 weeks to the standard 8 - week regimen to determine if rates
of cure were similar.
The guideline recommendations were developed by a multinational and multidisciplinary panel
of oncology, obstetrics / gynecology, public health, cancer control, epidemiology / biostatistics, health economics, behavioral / implementation science, and patient advocacy experts, including some
of the world's foremost
research leaders on HPV and HPV vaccines.
The largest Phase 1 study in the history
of oncology, the
research was conducted at UCLA and 11 other sites in the U.S., Europe and Australia.
For men with intermediate risk prostate cancer, side effects at two years following radiation therapy (RT) were comparable for extremely - hypofractionated treatment, which was delivered in seven fractions across two and a half weeks, and conventional treatment
of 39 fractions across eight weeks, according to
research presented at the 58th Annual Meeting
of the American Society for Radiation
Oncology (ASTRO).
Professor Paolo Boffetta (MD), the Annals
of Oncology associate editor for epidemiology and Director
of the Institute
of Translational Epidemiology at the Icahn School
of Medicine at Mount Sinai in New York (USA), commented: «These results are extremely important in showing that reducing cancer mortality can be achieved: priority should be given to
research in cancers with unfavourable trends, such as pancreatic cancer, and in reducing cancer mortality disparities, both between countries (Central / Eastern versus Western Europe), and within countries, for example, between socioeconomic groups.
«This study forms the basis for future
research in patients with breast cancer and offers hope for targeted therapy for patients with aggressive triple - negative inflammatory breast cancer,» said lead researcher Mateusz Opyrchal, M.D., Ph.D., Assistant Professor
of Oncology at RPCI.
The firm dropped discovery and development in the areas
of diabetes, virology, and neuroscience in favor
of a
research focus on
oncology, heart failure, genetically defined diseases, immunoscience, and fibrotic diseases.
People diagnosed with cancer gained 3.34 million years
of life thanks to cancer clinical trials run by SWOG and supported with public funds, according to new study results to be presented at the 53rd Annual Meeting
of the American Society
of Clinical
Oncology (ASCO), the world's largest clinical cancer
research meeting.
Researchers at the Bellvitge Biomedical
Research Institute
of Bellvitge, the Catalan Institute
of Oncology and the University Hospital
of Bellvitge have participated in an international study published in the journal Cancer Cell that describes how exosomes secreted by tumor cells contain protein and microRNA molecules capable
of transform neighboring cells into tumoral cells promoting tumor growth.
Other UT Southwestern faculty members who contributed to this
research are: Dr. Boning Gao, Assistant Professor with the Hamon Center for Therapeutic Oncology Research and Pharmacology; Dr. Kimmo Hatanpaa, Associate Professor of Pathology; Dr. Kemp Kernstine, Professor of Cardiovascular and Thoracic Surgery and holder of the Robert Tucker Hayes Foundation Distinguished Chair in Cardiothoracic Surgery; Dr. Yang Xie, Associate Professor of Clinical Sciences and Bioinformatics; Dr. Hong Zhu, Assistant Professor of Clinical Sciences and with the Simmons Cancer Center; Dr. Farjana Fattah, Assistant Professor with the Simmons Cancer Center and Pathology; Dr. Masaya Takahashi, Associate Professor with the Advanced Imaging Research and Radiology; Dr. Bipasha Mukherjee, Assistant Professor of Radiation Oncology; Dr. Sandeep Burma, Associate Professor of Radiation Oncology; and Dr. Jonathan Dowell, Professor of Internal M
research are: Dr. Boning Gao, Assistant Professor with the Hamon Center for Therapeutic
Oncology Research and Pharmacology; Dr. Kimmo Hatanpaa, Associate Professor of Pathology; Dr. Kemp Kernstine, Professor of Cardiovascular and Thoracic Surgery and holder of the Robert Tucker Hayes Foundation Distinguished Chair in Cardiothoracic Surgery; Dr. Yang Xie, Associate Professor of Clinical Sciences and Bioinformatics; Dr. Hong Zhu, Assistant Professor of Clinical Sciences and with the Simmons Cancer Center; Dr. Farjana Fattah, Assistant Professor with the Simmons Cancer Center and Pathology; Dr. Masaya Takahashi, Associate Professor with the Advanced Imaging Research and Radiology; Dr. Bipasha Mukherjee, Assistant Professor of Radiation Oncology; Dr. Sandeep Burma, Associate Professor of Radiation Oncology; and Dr. Jonathan Dowell, Professor of Internal M
Research and Pharmacology; Dr. Kimmo Hatanpaa, Associate Professor
of Pathology; Dr. Kemp Kernstine, Professor
of Cardiovascular and Thoracic Surgery and holder
of the Robert Tucker Hayes Foundation Distinguished Chair in Cardiothoracic Surgery; Dr. Yang Xie, Associate Professor
of Clinical Sciences and Bioinformatics; Dr. Hong Zhu, Assistant Professor
of Clinical Sciences and with the Simmons Cancer Center; Dr. Farjana Fattah, Assistant Professor with the Simmons Cancer Center and Pathology; Dr. Masaya Takahashi, Associate Professor with the Advanced Imaging
Research and Radiology; Dr. Bipasha Mukherjee, Assistant Professor of Radiation Oncology; Dr. Sandeep Burma, Associate Professor of Radiation Oncology; and Dr. Jonathan Dowell, Professor of Internal M
Research and Radiology; Dr. Bipasha Mukherjee, Assistant Professor
of Radiation
Oncology; Dr. Sandeep Burma, Associate Professor
of Radiation
Oncology; and Dr. Jonathan Dowell, Professor
of Internal Medicine;
The study was led by Dr. Alexandre Zlotta, Director
of Uro -
Oncology at Mount Sinai Hospital, and researcher with the Lunenfeld - Tanenbaum
Research Institute, part
of Sinai Health System in Toronto, Canada, and Dr. Paul Boutros, Principal Investigator, Informatics and Bio-computing, Ontario Institute for Cancer
Research (OICR).
These include the ability to bring new, innovative products to the market; progress in
oncology, such as the approval
of Genentech's drug Avastin for breast cancer and advances in the use
of gene therapy, despite some setbacks; continuing progress in
research on stem cells; the emergence
of treatments for previously untreated diseases; and solutions for food and fuel shortages, such as biocrops and biofuels.
Until now, EGFR inhibitors have only been effective at treating the 10 to 15 percent
of non-small cell lung cancers that have a variant
of EGFR, but the two - drug combo could potentially work for all non-small cell lung cancers, explained Dr. John Minna, Director
of the Hamon Center for Therapeutic
Oncology Research and Professor
of Internal Medicine and Pharmacology.
A recent study by researchers from the Manchester Cancer
Research Centre, published in the journal Annals
of Oncology, has explored potential subtypes
of DCIS and whether these subtypes relate to disease recurrence.
This
research also sheds light on which patients we should watch more closely,» said lead study author Anja Mehnert, PhD, a professor
of psychosocial
oncology at the University
of Leipzig in Germany.
«It was kind
of fun being at a medical school and known as the weird guy who worked with dogs,» says Modiano, who is now a professor
of comparative
oncology at the University
of Minnesota College
of Veterinary Medicine and the Masonic Cancer Center, where his
research focuses on immunology, cancer cell biology, cancer genetics, and applications
of gene therapy.
The
research team, led by senior author Timothy P. Cripe, MD, PhD, chief
of the Division
of Hematology /
Oncology / BMT at Nationwide Children's Hospital, found that virotherapy doesn't always require a strong virus infection
of cancer cells to cause tumors to shrink or die.
She worked with Ganz for 3 years as a junior scientist, learning about cancer and chronic disease and charting a course in the relatively new field
of psycho -
oncology before applying for her own
research funding.
«While the presence
of lymphocytes in tumors is often associated with better clinical outcomes, this
research adds clarity on the diversity
of T cells within the tumor environment and their influence on ovarian cancer outcomes,» says first author Kunle Odunsi, MD, PhD, FRCOG, FACOG, Deputy Director, M. Steven Piver Professor and Chair
of Gynecologic
Oncology, and Executive Director
of the Center for Immunotherapy at Roswell Park.
«This work is an example
of how integrating basic science and clinical care may reveal privileged opportunities for biomedical
research,» said Matthew O. Hebb, M.D., Ph.D., FRCSC, a researcher involved in the work from the Departments
of Clinical Neurological Sciences (Neurosurgery),
Oncology and Otolaryngology at the University
of Western Ontario in Ontario, Canada.
Dr Gerrit - Jan Liefers (MD, PhD), a surgical oncologist and head
of the geriatric
oncology research group at Leiden University Medical Centre (Leiden, The Netherlands), said: «For a screening program to be effective, one would expect that the incidence
of early stage breast cancer would increase while the incidence
of advanced stage cancer would decrease because any cancer would have been detected at an earlier stage.
«We knew that ANG was involved in promoting cell growth so it was not unexpected to find that ANG stimulates proliferation
of myeloid progenitor cells,» said Guo - fu Hu, PhD, Investigator in the Molecular
Oncology Research Institute at Tufts Medical Center, and the paper's senior author.
The
research was funded by a National Science Foundation Graduate Research Fellowship, a Mazumdar - Shaw International Oncology Fellowship, the Ruth L. Kirschstein National Research Service Award from the National Institutes of Health, the Burroughs Wellcome Fund, the National Cancer Institute, and the Howard Hughes Medical In
research was funded by a National Science Foundation Graduate
Research Fellowship, a Mazumdar - Shaw International Oncology Fellowship, the Ruth L. Kirschstein National Research Service Award from the National Institutes of Health, the Burroughs Wellcome Fund, the National Cancer Institute, and the Howard Hughes Medical In
Research Fellowship, a Mazumdar - Shaw International
Oncology Fellowship, the Ruth L. Kirschstein National
Research Service Award from the National Institutes of Health, the Burroughs Wellcome Fund, the National Cancer Institute, and the Howard Hughes Medical In
Research Service Award from the National Institutes
of Health, the Burroughs Wellcome Fund, the National Cancer Institute, and the Howard Hughes Medical Institute.
Alexander Anderson, Ph.D., chair
of the Department
of Integrated Mathematical
Oncology (IMO) and Mark Robertson - Tessi, an applied
research scientist in IMO, recently published a commentary on an integrative approach used to study cancer heterogeneity.
Connecting a global network
of more than 40,000 cancer professionals, the society serves as the leading resource for best practices in clinical
oncology research and academic and community practices.
In this case, the
research team visited the
oncology department
of a Madrid hospital and found that low white cell levels in patients were making them susceptible to life - threatening infections.
The trials were supervised by Gerald Beattie
of the Imperial Cancer
Research Fund's Medical
Oncology Unit in Edinburgh.
Principal investigator Leena Gandhi, MD, PhD, director
of the thoracic medical
oncology program at Perlmutter Cancer Center at NYU Langone Health and associate professor of Medicine in the division of Medical Oncology at NYU School of Medicine, presented these findings April 16 at the American Association for Cancer Research (AACR) Annual Meeting 2018 in
oncology program at Perlmutter Cancer Center at NYU Langone Health and associate professor
of Medicine in the division
of Medical
Oncology at NYU School of Medicine, presented these findings April 16 at the American Association for Cancer Research (AACR) Annual Meeting 2018 in
Oncology at NYU School
of Medicine, presented these findings April 16 at the American Association for Cancer
Research (AACR) Annual Meeting 2018 in Chicago.
New
research presented at the American Society
of Clinical
Oncology (ASCO) 53rd Annual Meeting in Chicago shows that a previously untested combination
of a monoclonal antibody - drug conjugate with a common chemotherapy agent has a high complete - response rate in children and young adults with relapsed or refractory Hodgkin lymphoma.
Principal investigator E. Shelley Hwang, M.D., chief
of breast surgery at the Duke Cancer Institute and vice chair
of research in the Duke University Department
of Surgery, will lead the study through the cooperative group, The Alliance for Clinical Trials in
Oncology.