A doctor in Oklahoma has been charged with five counts of second - degree murder after her patients died because
of opioid drug overdose.
The stereotype - shattering nature
of the opioid drug crisis, both in Erie County and nationwide, has not gone unnoticed by activists in the black community who remember when the crack epidemic swept through low - income, urban neighborhoods in the 1980s and early»90s, leading to a spike in violent crime and homicides.
In contrast, positive expectations of treatment doubled the natural physiological or biochemical effect
of the opioid drug among the healthy volunteers in the study.
However, Spicer then signaled that the White House sees recreational pot very differently, with the press secretary even attempting to link recreational use of the drug to the abuse
of opioid drugs across the U.S. (In fact, there has been little scientific evidence linking marijuana legalization to opioid use, with some studies actually showing a decrease in opioid overdoses in states where legal marijuana is available.)
From 2003 through 2007, Simmons, Hanly & Conroy represented 5,000 individual plaintiffs in a class - action lawsuit against Purdue Pharma regarding the use
of opioid drugs, according to the county.
The nation's largest pharmacy benefit manager, Express Scripts, will soon limit the number and strength
of opioid drugs prescribed to first - time users as part of a wide - ranging effort to curb an epidemic affecting millions of Americans.
Last June, Gov. Andrew Cuomo signed legislation that initially limits physicians from prescribing more than a seven - day supply
of opioid drugs.
But because of the high potency
of opioid drugs sold and used in Erie County, emergency personnel often find they need to use multiple doses to revive overdose victims.
Randall Bond, an ER doctor and pediatrician at the Cincinnati Children's Hospital who led the study, says the uptick coincides with a dramatic boost in sales
of opioid drugs.
«Pain sensitivity is a major issue for users
of opioid drugs because the more you take, the more the drug can increase your sensitivity to pain, so you may never quite get the level of relief you need.
Suing the manufacturers
of opioid drugs is no help with the problem of abuse (13 May, p 25).
So I was pleased to hear that there's a reason I inflict this pain on myself: grains have been proven to be addictive, mimicking the effects
of opioid drugs.
When mice were given a daily saccharin solution for 28 consecutive days, morphine no longer resulted in any amount of the typical analgesia.17 In other words, the tolerance of opioids in the mice was increased from the sweet taste of saccharine, necessitating larger doses
of opioid drugs to achieve similar analgesic effects.
The use
of opioid drugs must be monitored carefully by a veterinarian, particularly in dogs with heart condtions.
Not exact matches
The agents were particularly interested in the facility's practices when it came to an even smaller subset
of those scheduled
drugs: the highly addictive pain medicines containing oxycodone and hydrocodone that have been at the center
of the nation's
opioid epidemic.
These devices dispense a
drug called buprenorphine — itself an
opioid, but one that doesn't produce the sort
of euphoric and addictive high that more powerful painkillers such as OxyContin and morphine do.
U.S. Attorney General Jeff Sessions» wide - ranging new crackdown on
drug offenders could exacerbate one
of America's most persistent public health tragedies: the heroin and
opioid addiction epidemic that's been ravaging the country and killed nearly 35,000 Americans in 2015 alone.
It's been a busy week for health care news between some high - profile setbacks for certain major cancer
drug makers, high - profile victories for others, the confirmation
of a new FDA chief, health care merger drama, and a slew
of public health reports about the
opioid epidemic, hepatitis C, and U.S. life expectancy.
And the
opioid epidemic is at the forefront
of this crisis, with fears the
drugs could kill nearly 500,000 people over the next decade.
Taking dangerous quantities
of the otherwise safe loperamide is one strategy being used by people addicted to
opioid painkillers and other
drugs since it can increase
opioid absorption in the gut; the FDA says it is now working with loperamide manufacturers to change its packaging so that it comes with fewer doses and is thus harder to abuse.
After all we're just talking about social media, this isn't a campaign to raise awareness about illegal
drugs or the abuse
of prescription
opioids.
The Food and
Drug Administration (FDA) is working with manufacturers to tweak the packaging
of loperamide, a common OTC and prescription anti-diarrhea medication that is now also being used by people addicted to
opioids to stem withdrawal symptoms or enhance their highs.
One key factor contributing to the trend is the major spike in fatalities related to
drugs, including prescription painkillers containing addictive
opioids (like oxycodone and fentanyl) and illegal
drugs like heroin; another is the second straight year that gun deaths have risen after 15 years
of remaining relatively stable.
While evidence is anecdotal, some employers seem set to continue
drug testing all applicants and taking a hard line on use
of opioids, methamphetamine, and cocaine.
And for 27 years, before he was elected sheriff, he presided over court cases — ones that increasingly involved the stories
of lives undone by
drugs and poverty, and
of an
opioid epidemic taking root.
Although the offer
of DisposeRX for free is coming as a result
of the
opioid epidemic, the product works on any type
of prescription
drug, according to Holaday.
The most addictive
drugs, like prescription
opioids, are held in a so - called vault and packaged in specially sealed plastic bags by background - checked workers under the gaze
of several cameras.
A new government - funded study suggests that addictive
opioid painkillers may not be better than other, non-
opioid kinds
of drugs for treating chronic back pain and arthritis.
In 2011, 31 %
of prescription -
opioid - related overdose deaths involved these two kinds
of drugs used together, according to the National Institute on
Drug Abuse.
The call to execute certain
drug traffickers is drawing the most attention, but another part
of the plan could make a big difference: The White House will support research into developing a vaccine for
opioid addiction.
Other pain points included
drug pricing and how approving more generics may affect costs (Gottlieb parried that question by noting the FDA doesn't have the authority to negotiate prices or consider pricing when approving a
drug) and his alleged softness on
opioid drug makers due the aforementioned financial ties and pro-industry ideology (the nominee noted that he considers
opioid addiction and overdoses a public health crisis «on the order
of Ebola and Zika»).
Those provisions, she said, outweighed the «tiny fig leaf»
of additional money the bill provides for biomedical research and combating abuse
of addictive
opioid drugs.
The US is suffering from a deadly
opioid epidemic, especially in rural areas, thanks to the widespread use
of drugs like OxyContin as painkillers.
Her company is best known for jacking up the price
of life - saving EpiPen anti-allergy medication, but it also manufactures naloxone, a
drug meant to treat
opioid over-doses.
He points out a couple factors that make it hard to assign blame when it comes to the
opioid epidemic — pain meds are lawful
drugs, approved and regulated by the federal government, and there are «a whole lot
of intermediaries: in the distribution process.
The White House report on the epidemic says that 142 Americans die
of drug overdoses every day, and urges measures like federal legislation that would boost widespread adoption
of naloxone, an
opioid overdose antidote.
That number is based on prescriptions by morphine milligram equivalents, a metric that takes into account the strength and dosage
of drugs, but the total number
of filled
opioid prescriptions also dropped by 10.2 % per month, according to the report.
CVS, for example, began limiting prescriptions to seven days and prioritizing lower - dose
drugs, and a number
of legal complaints have been leveled against
opioid manufacturers, who have been accused
of using misleading marketing tactics that may have caused more patients to get hooked on potentially addicting painkillers.
Since fentanyl is so much more potent than other
opioid painkillers,
drug traffickers only need to pack their
drugs with small amounts
of it to provide users a powerful punch.
MINNEAPOLIS (AP)-- Some
of the pills taken from Prince's estate in Paisley Park after his death were counterfeit
drugs that actually contained fentanyl — a synthetic
opioid 50 times more powerful than heroin, an official close to the investigation said.
Amphastar became yet another
drug price - hiking villain facing intense public scrutiny when it raised the price
of naloxone, an
opioid overdose antidote, by more than 100 %.
For decades, naloxone, a
drug approved in 1971 that instantly reverses the effect
of opioid overdose, languished in relative obscurity.
In a 2015 report on national
drug threats, DEA officials stated that fentanyl was «unlikely to assume a significant portion
of the
opioid market.»
The
opioid antagonist Naloxone, or Narcan, instantly stops the effects
of a
drug overdose when administered.
In a statement released Friday, coroner Jonathan Lucas said that Petty's system showed signs
of several
opioid painkillers, including fentanyl and oxycodone, in addition to the other
drugs.
«Even if it remains a Schedule I substance, the DEA will continue to allocate its resources and time to the biggest and most violent
drug traffickers,» he says, explaining most
of the agency's resources are being used to deal with the current
opioid epidemic, which kills more people each year than auto accidents.
Drug companies including Purdue Pharma LP and Johnson & Johnson have been fighting lawsuits by two California counties, the city
of Chicago, four counties in New York and the state
of Mississippi over their
opioid marketing practices.
Citing data from the Substance Abuse and Mental Health Services Administration and the National Institute
of Drug Abuse, Walmart said some 65 %
of opioid abusers get them from unwitting family and friends.
Several West Virginia counties have filed lawsuits in recent months against
drug wholesalers McKesson Corp, Cardinal Health and AmerisourceBergen for failing to report suspicious orders
of opioids in the state.
In this era
of marijuana legalization and
opioid overdoses, it was encouraging to see the attorney general call attention to
drug education for the young.