Sentences with phrase «of optogenetic»

However some technical challenges still need to be taken to make the technology more accessible and usable to its full potential: gaining selective and comprehensive genetic access to the neurons of interest, controlling variation in the expression of the optogenetic tools (when using viruses) and its precise localization (axon vs. presynaptic terminals), tailoring light - delivery system signals to individual cells in a population rather than the population as a whole, developing observation techniques which have the same spatial and temporal resolution as those tools... to cite only a few of them.

Since 2005, improvements to early techniques have provided the community with a very powerful kit of optogenetic tools.

When using the DanioVision Observation Chamber, the Optogenetics Add - on provides a way to accurately control and precisely time the application of optogenetic stimulation to up to 98 individuals simultaneously (working with 98 well plates).

development of an optogenetic toolbox for real - time modulation of the olfactory processing network

In one example, the research team put the production of an antidiabetes peptide in mice under the control of an optogenetic switch, allowing them to regulate glucose levels in the animals just by shining light on them.

Eric Topol speaks with Edward Boyden about the promise of optogenetics, from treating common brain disorders to unlocking what it means to be human.

Using the new science of optogenetics, scientists can activate or shut down neural pathways, altering behavior and heralding a true cure for psychiatric disease.

Read more about the promise of optogenetics: Fixed by light: Flick a switch to banish pain and blindness

Most compelling, however, are experiments that have demonstrated te relevance of optogenetics to both basic science and medicine.

The import of optogenetics for consciousness is that it allows testing of a specific hypothesis about the neural basis of consciousness.

There has been talk of optogenetics for the blind, implanting opsins in vision cells and developing special glasses that shine light into them.

Every two weeks, scientists come from universities in the United States and abroad to spend a week at the D - lab learning the secrets of optogenetics, mastering everything from mouse surgery to cooking up viruses.

With the help of optogenetics, the research group was able to deactivate specific genetically altered brain cells using light.

Using this material, the researchers were able to analyse in detail the response of rhodopsin, the pigment protein underlying vision, and phosphodiesterase, and for this reason they believe it can be useful in the field of optogenetics in the future.

Dr. Gradinaru completed her B.S. at Caltech and her Ph.D. research at Stanford University, where she played an instrumental role in the early development and applications of optogenetics.

Dr. Deisseroth led the development and application of optogenetics as well as CLARITY, which enables high throughput whole brain analysis of wiring and fine structure without disassembly.

As MIT's Edward Boyden, one of the co-developers of optogenetics, noted at the briefing, the brain is incredibly dense and varied.

But Boyden said the primary clinical impact of optogenetics will arise, almost certainly, from the science that it enables.

A novel twist on the young field of optogenetics may provide a new way to study living human brains as well as offering innovative therapeutic uses.

Other groups are exploring different therapeutic applications of optogenetics, including treatments for epilepsy and Parkinson's disease

You may have heard of optogenetics.

And that is the impact of optogenetics: controlling neuronal activity by switching a light on and off.

Early in his career, Dr. Zhang was a co-inventor of optogenetics, a new neuroscience technology.

Boyden was honored for the development and implementation of optogenetics, a technique in which scientists can control neurons by shining light on them.

«We are trying to build a novel technology that enables us to control a selected protein simply using light, moving the resolution of optogenetics from the cellular level to the molecular level,» said Wang, associate professor of Pharmaceutical Chemistry.

As the application of optogenetics in the field of zebrafish neurobiology increases, so does the need for efficient protocols.

This led her to apply for a postdoctoral fellowship with the celebrated neuroscientist Karl Deisseroth at Stanford University, who pioneered the field of optogenetics.

He is an expert in the emerging field of optogenetics — the application of genetic and optical techniques to remotely control brain cells in animals.

As part of the study the team first used a form of optogenetics to establish that if gamma oscillations are increased, they will energize microglial cells in areas such as the hippocampus.

«The beauty of optogenetics is that there is no negative impact on normal brain activity,» says Dr. Paz.

Working with heart - muscle cells, Bonin says, «is an interesting new application of the tools of optogenetics.»

The idea of optogenetics, which is a way to control genetically modified neurons with light, was conceived decades ago.

Not exact matches

Applying tools from optogenetics with ideas from regenerative medicine may herald a new era of translational optogenetics.

In this web exclusive, the author offers a longer version of his December 2010 Scientific American article on how researchers can probe how the nervous system works in unprecedented detail, using a technique called optogenetics

Focusing on the neural pathway from the brain's prefrontal cortex to the amygdala, they combined optogenetics — a technique that uses light to control the activity of neurons in living tissue — with behavioral testing, a methodology that allows researchers to study functional connections between different regions of the brain.

Optogenetic activation of NR neurons in awake behaving mice revealed the role of the NR in fear memory generalization.

Instead of just observing the effects from a drug or an implanted electrode, optogenetics brings researchers closer to the fundamental causes of a behavior.

Last spring Deisseroth's group published an optogenetics study that helped to elucidate the workings of deep - brain stimulation, which uses electrodes implanted deep in the brain to alleviate the abnormal movements of Parkinson's disease.

«Together, we were able to combine state - of - the - art optogenetic approaches with cutting edge nanotechnology.»

However, we use optogenetics to systematically stimulate certain unaffected areas of the brain so that they sprout connections into the damaged hemisphere in order to assume its functions.»

Researchers in optogenetics can control genetically modified brain cells using light but because of these modifications, the technique is not yet deemed safe to use in humans.

At the Society for Neuroscience meeting in Chicago last October, Michael Häusser of University College London reported on an optogenetics experiment that showed how 100 neurons could trigger a memory stored in a much larger ensemble of about 100,000 neurons, suggesting how the technique may be used to understand memory formation.

Optogenetics experiments have helped illuminate the biological bases of complex behaviors such as addiction and sleep.

Other researchers have used optogenetics to transmit artificial skin sensations into the brains of mice, but Ko plans to investigate other technologies to find a technique that's best suited for his lab's e-skin.

Chemogenetics builds on optogenetics, which involves genetically engineering brain cells so that they fire in the presence of light.

One way to image these cause - and - effect relationships is through optogenetics, which involves genetically engineering mice so that their neurons fire when hit with a beam of light shone through the skull.

«Optogenetics... is not something I'm willing to have done to me, in spite of the potential for making me a hit at parties.»

Neuroscientists are now using optogenetics to map brain activity and test the effectiveness of an on / off switch in treating disorders.

When researchers used optogenetics — a technique that allows cells to be switched on and off with light — to increase the amount of bursting in the lateral habenula, mice behaved in a more «depressed» way, remaining motionless when forced to swim in a container of water, for example.

A technique known as optogenetics, for example, lets researchers study the function of individual neurons by genetically altering them so they can be turned on and off by a light switch.