Moreover, three - dimensional (3D) μCT reconstruction of the tibia revealed that mice injected with control cells had a significantly higher degree
of osteolysis with a decreased ratio of bone volume to total volume compared to mice injected with ABL1 / ABL2 knockdown breast cancer cells (Fig. 4, E and F).
Calcification can be found at the center
of the osteolysis giving it a characteristic appearance [8].
Intravital microscopy of prostate cancer lesions in bone: kinetics
of osteolysis and therapy response.
Intravital microscopy of prostate cancer lesions in bone: Kinetics
of osteolysis and therapy response.
Not exact matches
The artwork appeared on the front cover
of Applied Surface Science summarizes the benefits
of a new bioceramic coating versus the commercially available Calcium Phosphate which develops microcracks during processing and may later cause
osteolysis in load - bearing orthopedic implants.
There are also problems with the long - term performance
of implants, such as release
of debris from bioactive films which can potentially lead to
osteolysis and chronic inflammation.»
These findings reveal a function for ABL kinases in the regulation
of breast cancer bone metastasis and tumor - induced
osteolysis in vivo.
Moreover, we found that treatment with a selective allosteric inhibitor
of the ABL kinases or simultaneous depletion
of both ABL kinases in breast cancer cells impaired breast cancer bone metastases and decreased osteoclast activation in vitro and
osteolysis in vivo.
We found that allosteric inhibition
of the ABL kinases effectively impaired breast cancer bone metastasis and blocked tumor - induced
osteolysis in mouse models.
Problems stemming from the implant may include fretting and corrosion, loosening
of the hip implant, metallosis (metal poisoning),
osteolysis, bone deterioration, fractures, and dislocation.
Two months before the recall, Stryker is reported to have put out a warning to medical professionals and affected parties over concern that the rubbing together
of its parts could Adverse Local Tissue Reaction, including necrosis, metallosis,
osteolysis, tumor - like formations, and pain serious enough to warrant revision surgery.