Other autoimmune diseases: if you or family members
of other autoimmune diseases, like lupus, multiple sclerosis, or rheumatoid arthritis, for example, you have an increased risk of thyroid problems.
It is absolutely necessary to establish Th1 or Th2 dominance of the immune system to create a most effective treatment in order to stop the attack on the thyroid, achieve the balance and prevent development
of other autoimmune diseases.
Undiagnosed, and hence, untreated, Celiac Disease is associated with anemia, osteoporosis, arthritis, infertility, central nervous system damage, and the development
of other autoimmune diseases.
Not exact matches
Founded in 2011, Innovent has built a portfolio
of 16 potential products for treating cancer,
autoimmune disorders and
other diseases, and seven
of those are in clinical development.
If you have been on the SAD diet (Standard American) & have an
autoimmune disease, diabetes, or
other health problems, the Paleo Diet is one
of the best diets I have found.
Hi I have suffered so much from the
Autoimmune diseases such as Hypothyroid, sjogrens abd raynauds with host
of other problems.
Other causes
of low milk supply include thyroid disorders, pieces
of retained placenta, which would likely be accompanied by abnormal postpartum bleeding, polycystic ovary syndrome, which involves an imbalance
of sex hormones, and Sjogren's syndrome, an
autoimmune disease.
Food allergies and intolerances join the ranks
of other rapidly growing disorders in children and are often the first signs
of future GI ailments and
autoimmune diseases.
In one form or another, this diet keeps reappearing as a recommendation for a number
of problems — autism,
autoimmune disease among
others.
Its consumption can worsen the condition
of certain
autoimmune diseases such as lupus and multiple sclerosis, breast cancer, ovarian cancer and
other uterine problems.
Poor gut flora is also linked to initiation
of autoimmune diseases involving
other parts
of baby's body — such as asthma, diabetes,...
«This is a universal molecule that can potentially treat not only
autoimmune diseases, but
other acute or chronic conditions such as allergy, chronic obstructive pulmonary
disease, sepsis and immunodeficiency,» said Stefan G. Tullius, MD, PhD, BWH Chief
of Transplant Surgery and Director
of Transplantation Surgery Research, lead study author.
«We're always looking for ways to mitigate risk, and our first - time finding points to a novel environmental factor that also might help us to determine the cause
of this and
other devastating
autoimmune diseases.»
The genetic variants associated with asthma have also effects on
autoimmune diseases and
other diseases with an inflammatory component such as cardiovascular
diseases, cancers, neuro - psychiatric
diseases, which strengthens the importance
of pleiotropy in multifactorial
diseases.
Further work showed that genetic differences affecting some
of these characteristics are linked to increased risk
of heart attack, or to rheumatoid arthritis and
other common
autoimmune diseases.
Gaining a better understanding
of the underlying
disease mechanisms could offer the possibility
of developing new and better treatments for lupus and
other autoimmune conditions in the future.
«Our study reveals a new mechanism that could be harnessed for biological therapies for lupus and
other autoimmune diseases, where the immune system mistakenly targets the body's own cells,» says senior study author Boris Reizis, PhD, professor
of Pathology and Medicine at NYU Langone.
If the delivery
of this technology proves successful in patients with rheumatoid arthritis, it could also be applied to
other autoimmune diseases such as Type 1 diabetes.
It is possible that this type
of reaction to alien substances may also be involved in
other autoimmune diseases.
And over the last eight or nine years we've looked at the general world
of unmet needs such as an oncology franchise,
autoimmune disorders, and
other diseases.»
Four
of them show a strong correlation with known loci for not only atopic dermatitis and asthma, but also for
other chronic inflammatory
diseases like Crohn's
disease and psoriasis as well as
autoimmune disorders.
«The identification
of a new inflammatory target in rheumatoid arthritis holds promise for better treatment for these patients and perhaps those with
other autoimmune or inflammatory
diseases.»
Autoimmune diseases arise from an overactive immune response
of the body against substances and tissues normally present in the body; in
other words, the body attacks its own cells.
Our new semi-immortals, people
of indefinite and unknown longevity, would be a diverse population resistant to all viruses, known and unknown, all
other pathogens, and all forms
of cancer,
autoimmune diseases, environmental toxins, and even radiation — that last attribute particularly handy for space travel.
If I had gone that
other route, I would most likely be studying basic mechanisms
of immunity rather than applying them to the study
of infectious and
autoimmune disease models.
We also observed some similarities between our findings and
other emerging gut microbiota studies in multiple sclerosis; whether these indicate a «gut signature»
of multiple sclerosis or
of broader
autoimmune disease remains to be determined,» said Professor Helen Tremlett, lead author
of the European Journal
of Neurology study.
The findings also point to the potential for new therapies for lupus and
other autoimmune disease based on inhibiting the action
of EBNA2 or
other human proteins that bind to DNA at the same loci along with the viral protein, the researchers say.
A compound derived from immune cells treats psoriasis in mice and holds promise for
other autoimmune diseases, according to a new study from Washington University School
of Medicine in St. Louis.
These cells were not affected in patients with SLE, dermatomyositis, or
other type I interferonopathies, however, suggesting that the source
of interferon - can vary depending on the
autoimmune disease.
Monitoring immune cell activity — including phenotyping immune cell subsets, tracking cell proliferation, and measuring cytokine production — can provide insights into the overall status
of immune function in patients, particularly those undergoing immunosuppression after transplants, enduring cancer treatment, or suffering from
autoimmune disease or
other pathologies that affect the immune system.
The survey shows that 45 %
of respondents had a family member with an
autoimmune disease other than Crohn's.
Common causes
of pulmonary hypertension include congestive heart failure,
other heart
diseases, birth defects
of the heart, chronic lung
disease, obstructive sleep apnea, and certain
autoimmune disease such as rheumatoid arthritis.
With these cells in hand, the researchers injected them into the lacrimal glands
of mouse models
of Sjogren's syndrome, an
autoimmune disease that results in ADDE, dry mouth and
other symptoms.
It turned out that, in some people with a specific genetic variant, the vaccine, Pandemrix, caused narcolepsy and this generated a lot
of discussion as to whether
other autoimmune diseases may be induced by the vaccine.
There has been a fear that the swine flu vaccine, Pandemrix, would increase the risk
of autoimmune diseases other than narcolepsy.
Other forms
of PAH can be triggered by
autoimmune diseases, congenital heart defects, infections (such as schistosomiasis), and medications (such as the now - banned diet - drug combination commonly known as fen - Phen).
There are many
other known causes
of inflammation, including tissue injury and
autoimmune disease, although the researchers did not examine these specific conditions in this study.
«Furthermore, this strategy may be beneficial for
other pathological settings in which elevated numbers
of regulatory T cells are desirable, such as
autoimmune diseases and solid organ transplantation,» Beilhack says.
Marijuana abusers were excluded if they had a history
of substance abuse or dependence (
other than marijuana and nicotine), history
of other psychiatric or neurological
diseases, medical conditions that might alter cerebral function (i.e., cardiovascular, endocrinological, oncological,
autoimmune diseases), current use
of prescribed or over-the-counter medications, and / or head trauma with loss
of consciousness for more than 30 min.
It should radically transform our knowledge
of immune function and dysfunction in infectious
diseases,
autoimmune or inflammatory disorders, and the role
of immunocytes in
other diseases as diverse as cancer, type 2 diabetes, and psychiatric
disease.
«This study has significant implications for treatment
of diabetes and also
other autoimmune diseases,» said Ostrov, associate professor at the University
of Florida College
of Medicine's Center for NeuroGenetics.
Because it would not be feasible for a single laboratory to study each
of the 50 or more genes implicated in type 1 diabetes with this approach, they decided to prioritize those genes that are also associated with
other autoimmune diseases.
Timothy Springer, with colleagues Michael L. Dustin and Charles A. Dinarello, identifies and characterizes adhesion molecules, a class
of cell surface proteins that function in the interactions
of immune cells with
other cells, including antigen - specific recognition and cell trafficking: integrin LFA - 1 involved in cytoskeleton and signaling, and intracellular adhesion molecules (ICAMs), which are binding partners (ligands) for LFA - 1 and are increased in inflammatory and
autoimmune disease.
For more information regarding Bristol - Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com Inclusion Criteria: • Early stage IB - IIIA, operable non-small cell lung cancer, confirmed in tissue • Lung function capacity capable
of tolerating the proposed lung surgery • Eastern Cooperative Oncology Group (ECOG) Performance Status
of 0 - 1 • Available tissue
of primary lung tumor Exclusion Criteria: • Presence
of locally advanced, inoperable or metastatic
disease • Participants with active, known or suspected
autoimmune disease • Prior treatment with any drug that targets T cell co-stimulations pathways (such as checkpoint inhibitors)
Other protocol defined inclusion / exclusion criteria could apply
Escalier Biosciences develops topical and oral RORγt - based therapeutics for treatment
of psoriasis and
other autoimmune diseases
It turns out that rituximab can also work for
diseases such as rheumatoid arthritis, multiple sclerosis and
other autoimmune conditions in which overactive B cells in the immune system contribute to the inflammation and degradation
of healthy tissue.
With what we've recently come to understand in terms
of the
autoimmune response in type 1 diabetes, to what degree do you think this knowledge will be more generally applicable to
other autoimmune diseases such as Crohn's and lupus?
Other data with either gene - deficient animals or with agonist reagents to 4 - 1BB have highlighted another aspect
of biology in that a suppressive activity has been observed, for example, where stimulating 4 - 1BB in
autoimmune models
of MS or rheumatoid arthritis inhibits
disease progression and pathology.
In their search for such a trigger in people who had become narcoleptic, Mignot's group found elevated levels
of antibodies to Streptococcus pyogenes, a bacterium that causes strep throat and has been implicated in
other autoimmune diseases, such as rheumatic fever.
Patients suffering with chronic inflammatory
diseases, recurrent infection,
autoimmune diseases and
other disorders
of aging have also found promise in immune regenerative therapies.