Sentences with phrase «of other chemotherapy»

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Others have found that bacteria within the tumors themselves can influence the effectiveness of traditional chemotherapy as well.

«While we are disappointed CheckMate - 026 did not meet its primary endpoint in this broad patient population, we remain committed to improving patient outcomes through our comprehensive development program, including the ongoing Phase III CheckMate - 227 study exploring the potential of the combination of Opdivo plus [our other cancer immunotherapy] Yervoy for PD - L1 positive patients, and Opdivo plus Yervoy, or Opdivo plus chemotherapy in PD - L1 negative patients,» he added.

Past history of cancer: If you've had cancer in the past, ask your healthcare provider how long it will take for chemotherapy drugs and other medications to leave your system.

These include radioactive isotopes, antimetabolites, cancer chemotherapy agents, and a small number of other medications.

Additionally, due to other medical issues or poor performance status (a measure that considers a patient's quality of life and ability to function during treatment), some stage III NSCLC patients are unable to receive the standard treatment of concurrent chemotherapy and RT..

They also report that inhibition of the FA pathway coupled with chemotherapy maybe be useful for treating other types of cancer.

Once the disease spreads to other parts of the body, most patients are not candidates for surgery and receive chemotherapy as their primary treatment.

A transport vehicle the size of a virus may ferry chemotherapies and other molecular cargo through the imposing blood — brain barrier

In other research, Limoli examines the impact of chemotherapy and cranial irradiation on cognition.

The team then added either of two chemotherapy cocktails commonly used for colorectal cancer to the fishes» water and found that some of the tumors shrank and others didn't.

Chemotherapy and radiotherapy alone are relatively unsuccessful in treating the disease, and while surgery to remove the tumour offers the best chance of survival, most patients are diagnosed when the cancer has already spread to other organs.

Though many people can survive leukemia with chemotherapy and other drugs, Porter's patients had not responded to any of the available treatments.

Drugs that enhance a process called oxidative stress were found to kill rhabdomyosarcoma tumor cells growing in the laboratory and possibly bolstered the effectiveness of chemotherapy against this aggressive tumor of muscle and other soft tissue.

A transplant of hematopoietic stem cells attempts to cure patients with certain cancers and other serious illnesses that have not responded to conventional chemotherapies.

The study evaluated 56 patients with ovarian clear cell adenocarcinoma (CCA), an aggressive form of ovarian cancer that is more likely to be resistant to chemotherapy and to have a poorer prognosis than other forms of this disease.

«Pelvic RT after chemotherapy may be more beneficial in treating this form of ovarian cancer compared with other types,» Dr. Small said.

This blood vessel normalization results in an increased barrier function on the one hand — thereby blocking cancer cell dissemination and metastasis - and in enhanced tumor perfusion on the other hand, which increases the response of the tumor to chemotherapy.

«If, as we postulate, the combination of chemotherapy and PARP inhibition is successful in treating patients with HRD tumors, I expect that others will start exploring whether similar drugs or analogous therapies can make a difference in these diseases,» Heeke concludes.

Chemotherapy and other cancer treatments are supposed to get rid of the disease, but a new study finds they can elicit aggressive tumor growth instead, STAT reports today.

About half of the group (52.9 %) received other therapies such as chemotherapy, chemo - radiotherapy, or radiotherapy before surgery.

The same approach may be useful for boosting the effects of chemotherapy in other types of solid tumour with high levels of stroma, Ganss says.

As well as weakening the tumour, which makes it less able to grow and spread to other parts of the body, the drug made blood vessels become more leaky, enabling more chemotherapy drugs to spill into the tumour.

As part of the new study, the researchers showed that intact axons without Phr1 were protected from the damage caused by vincristine, a chemotherapy drug used to treat leukemia, neuroblastoma, Hodgkin's disease and non-Hodgkin's lymphoma, among other cancers.

In other words, patients with a methylation pattern resembling that of healthy people's HSCs (i.e., a «low score») would be more likely to live longer — and therefore benefit more from chemotherapy — than patients with a high score.

These genetic differences have often been blamed when chemotherapy or other treatments have been unsuccessful, as it was believed that the therapy may not have targeted all of the cells within the tumor.

Therefore, «this finding may represent a future therapeutic strategic to combine with other strategies, such as immunotherapy, chemotherapy or inhibitors against specific signalling routes of the tumour cells.»

Tamara Minko, professor in the Ernest Mario School of Pharmacy, and Lorna Rodriguez, professor of obstetrics, gynecology and reproductive sciences at Robert Wood Johnson Medical School, say because there is not a good screening method for ovarian cancer, most women with the disease are not diagnosed until after it has metastasized to other organs and surgery and chemotherapy are not as effective.

The median number of prior therapies for these patients was three; all the patients had been treated previously with at least one other EGFR TKI therapy, and most patients receiving chemotherapy as well.

More than half of all cancer chemotherapy treatments currently use platinum compounds, which were introduced nearly 40 years ago, so there is a need to explore the benefits which other precious metals could bring.

Current antifungals also have a narrow spectrum of activity, and some interact with other drugs such as chemotherapy agents and immunosuppressants.»

While chemotherapy prior to surgery can eradicate TNBC in approximately 30 percent of patients, in other patients the cancer behaves in a manner resistant to chemotherapy and often spreads or metastasizes to distant sites in the body, at which point there is no proven cure.

This can be useful to recommend that these tumors do not be conformed to surgery and determine that it will probably be necessary to administer adjuvant chemotherapy in other words, in those tumors with a more «benign» epigenetic pattern; surgery alone may be curative, thus avoiding the side effects of chemotherapy, «concludes the researcher.

Of those that had the high - risk signature, cancer spread to the lungs in 55 %, in spite of chemotherapy treatment, whereas only 10 % of the others showed cancer migration to the lungs — and even then, the lungs were not the principal or most aggressive site, the team reports 28 July in NaturOf those that had the high - risk signature, cancer spread to the lungs in 55 %, in spite of chemotherapy treatment, whereas only 10 % of the others showed cancer migration to the lungs — and even then, the lungs were not the principal or most aggressive site, the team reports 28 July in Naturof chemotherapy treatment, whereas only 10 % of the others showed cancer migration to the lungs — and even then, the lungs were not the principal or most aggressive site, the team reports 28 July in Naturof the others showed cancer migration to the lungs — and even then, the lungs were not the principal or most aggressive site, the team reports 28 July in Nature.

Furthermore, the agent prevented the drop in the number of neutrophils (i.e., neutropenia) found in the blood that is typically caused by 5 - fluorouracil, a chemotherapy agent commonly used in the treatment of gastrointestinal and other tumors, such as colon, stomach, pancreas and breast cancers.

Some oncologists offered the test to all their patients, others only to those who were eligible or where they felt there was uncertainty about the potential value of chemotherapy.

Current guidelines for treating early - stage breast cancer — cancer that has not spread to nearby lymph nodes or other parts of the body — result in thousands of women receiving chemotherapy without benefitting from it.

The study, led by Deborah Armstrong at the Johns Hopkins Kimmel Cancer Center in Baltimore, Maryland, builds upon evidence from eight other clinical trials showing an overall survival benefit of approximately one year for women treated with IP chemotherapy after «optimal debulking» — surgery to remove most, if not all, of the cancer in the abdomen.

Of the 4,868 women in this study, natural menopause was reported by 79 % of the women, 10 % as a surgical menopause and 11 % of women reported menopause due to other causes, such as radiation or chemotherapOf the 4,868 women in this study, natural menopause was reported by 79 % of the women, 10 % as a surgical menopause and 11 % of women reported menopause due to other causes, such as radiation or chemotherapof the women, 10 % as a surgical menopause and 11 % of women reported menopause due to other causes, such as radiation or chemotherapof women reported menopause due to other causes, such as radiation or chemotherapy.

He hopes the cancer - targeting nanorobots will steer clear of other rapidly dividing cells, such as those in the gut and at hair follicles, which often suffer collateral damage during chemotherapy.

In contrast, because of the high incidence of TP53 mutations in the HPV - inactive class, these tumors may be less responsive to the standard cisplatin chemotherapy and more sensitive to other chemotherapies such as dasatinib.»

Surgery, radiation and chemotherapy do prolong survival by several months, but targeted therapies, which have been effective with other forms of cancer, have not lengthened survival in patients fighting glioblastoma.

Drugs exist for the treatment of symptoms — pain relievers, for instance — but not for the condition itself, which can be caused by chemotherapy, diabetes, traumatic injury, heredity and other conditions.

Combination therapies often include multiple types of chemotherapy or chemotherapy combined with other treatment options.

«One is that it sheds light on how premalignant and early cancer cells are able to withstand the assault of chemotherapy and other treatments,» he says.

Since stem cells are also critical for regeneration in the intestine, therapies that target these pathways may further help to design new drugs that reduce side effects associated with chemotherapy, radiotherapy or other causes of intestinal damage.

A new breast cancer clinical trial is testing the idea a major reason why breast cancer returns after treatment and spreads to other parts of the body is because current chemotherapy and radiation treatments do not kill the cancer stem cells.

Depending on the type of cancer, your team may include a medical oncologist, who specializes in chemotherapy treatment; a radiation oncologist, who oversees radiation therapy; a surgeon who specializes in removing cancer; or other types of specialists.

After the chemotherapy drug has eliminated enough of the most prolific cancer cell types, the other cells that have survived are resistant to the drug and now have less competition for space and nutrients.

This may enable patients to avoid chemotherapy as well as radiation, which can permanently alter the pliability and function of the vagina as well as other organs in the pelvic region and even induce menopause in young women.

Bennett PM and others, Working Party of the British Society for Antimicrobial Chemotherapy (2004).