Yin's research also has implications for the treatment
of other diseases involving muscle damage, including muscular dystrophy.
The silver lining, says Richard Salmon, a retired neurologist who wrote an editorial accompanying the research, is that recent research shows that the vCJD prion behaves much like the pathological proteins behind a number
of other diseases involving brain degeneration, including Alzheimer's and Parkinson's diseases.
Not exact matches
In
other words with my trust that the Universe is a good and holy place I asked only that everyone
involved including the
disease itself, plug themselves into the spirit
of the Universe and let that spirit
of love guide their thoughts and actions.
Many are now literally feeling the effects
of such macronutrient skew either due to gluten sensitivity (or it could be due to another grain protein; we now realize that immunologic reactivity in celiac
disease may not be limited to wheat gluten, but can
involve certain nongluten proteins, too, see Nongluten wheat proteins triggered immune response in celiac patients), fructose malabsorption, or some
other food intolerance / sensitivity).
Other causes
of low milk supply include thyroid disorders, pieces
of retained placenta, which would likely be accompanied by abnormal postpartum bleeding, polycystic ovary syndrome, which
involves an imbalance
of sex hormones, and Sjogren's syndrome, an autoimmune
disease.
Certainly some
of these are
involved, as may be excessive processing
of foods, drug residues in foods and water, now - common deficiencies in DHA and vitamin D, excessive hygiene, lack
of challenging childhood
diseases, and likely
other nutritional and environmental causes we have yet to learn
of.
Poor gut flora is also linked to initiation
of autoimmune
diseases involving other parts
of baby's body — such as asthma, diabetes,...
Speakers included Dimitri Prybylski
of the U.S. - based Centers for
Disease Control (CDC), Namibia office, who was
involved in coordinating the international response to the Ebola virus outbreak in West Africa; Markus Theobald
of the EU Delegation to Namibia in Windhoek; and Pierguido Sarti, Italian science attaché to South Africa, Namibia, and
other southern African countries.
Though this research focused on the form
of the
disease called Leber congenital amaurosis 2, or LCA2, the scientists and engineers
involved in the study believe the technology holds promise for
other forms
of LCA as well as
other inherited
diseases that lead to severe vision loss or blindness.
Saxena's findings are corroborated by a recent study from the University
of Iowa,
involving a group
of people who had suffered lesions in various parts
of their brains as a result
of strokes or
other neurological
diseases.
Metabolic syndrome strikes about a third
of the adults in the United States and
involves multiple risk factors for heart
disease and
other health issues.
The neuroprotective effects
of nicotine were studied in a randomized clinical trial
involving 67 subjects in the early stages
of Alzheimer's
disease, where memory was slightly impaired but decision - making and
other cognitive abilities remained intact.
It is possible that this type
of reaction to alien substances may also be
involved in
other autoimmune
diseases.
University
of Adelaide researchers have developed a new theory for the causes
of dementia and
other neurodegenerative
diseases,
involving an out -
of - control immune system.
A string
of such beautiful, interventionist mice experiments over the past several years has revealed specific circuit elements
involved in a variety
of normal and pathological behaviors: depression, behavioral conditioning, Parkinson's
disease and cortical oscillations critical for attention, among
others.
By pairing a receptor that targets neurons with a molecule that degrades the main component
of Alzheimer's plaques, the biologists were able to substantially dissolve these plaques in mice brains and human brain tissue, offering a potential mechanism for treating the debilitating
disease, as well as
other conditions that
involve either the brain or the eyes.
This animation guides us through the immune pathways
involved in the
disease, from the first signs
of self - reactive immune cells to joint damage and
other symptoms.This article was reproduced with permission and was first published on January 25, 2016.
Carson and his colleagues plan future studies
involving PET imaging
of synapses to research epilepsy and
other brain disorders, including Alzheimer's
disease, schizophrenia, depression, and Parkinson's
disease.
The effects
of sauna bathing on the risk
of Alzheimer's
disease and other forms of dementia were studied in the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD), involving more than 2,000 middle - aged men living in the eastern part of F
disease and
other forms
of dementia were studied in the Kuopio Ischaemic Heart
Disease Risk Factor Study (KIHD), involving more than 2,000 middle - aged men living in the eastern part of F
Disease Risk Factor Study (KIHD),
involving more than 2,000 middle - aged men living in the eastern part
of Finland.
When the researchers looked at the pattern
of these genetic regions, they discovered that this differed from that
of those regions
involved in predisposition to
other common
diseases.
Produced by tasks such as grinding concrete and sandblasting, used in the construction and
other industries, crystalline silica dust can cause silicosis — an incurable
disease involving inflammation
of the lungs — and lung cancer.
The study
involved 1,531 men with newly diagnosed, clinically localized prostate cancer, meaning the
disease hadn't spread to
other parts
of the body.
Dr. Alan S. Cross, Professor
of Medicine at University
of Maryland School
of Medicine, who was not
involved in the research, shared his input: «This is a major conceptual breakthrough in our understanding
of infection and immune
disease mechanisms and may have implications for novel approaches to the treatment
of other diseases characterized by cytokine storm.
The treatment
involves an innovative use
of clinically approved treatments for
other diseases, so that, according to the authors, «it shouldn't be associated with adverse side effects.»
«Use
of induced pluripotent stem cell (iPSC) technology» — which
involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable
of turning into
other specific cell types relevant for studying a particular
disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie
of KU Leuven.
The findings suggest that RIPK1 may be
involved in a range
of other neurodegenerative
diseases marked by axonal damage, including multiple sclerosis, certain forms
of spinal muscular atrophy and even Alzheimer's
disease.
Wolynes considers the new study a beachhead to launch
others to determine the entire process
of how memories form, as well as the implications for
diseases like Alzheimer's and Parkinson's that
involve protein aggregation.
The University
of Florence team's 2011 statistical analysis
of health outcomes for almost 1,700 male patients showed that those
involved in stable extramarital relationships had about twice the cardiovascular
disease as
other patients in the study, particularly if the man reported that his wife was still sexually interested in him.
«Compared to
other ways
of trying to develop stem cells to treat blood
diseases, this method is safer and quicker, because it does not
involve using any artificial substances or any genetic modifications, merely a substance that already exists inside the body,» explains Kenichi Miharada.
Dopamine is also
involved in many
other biological processes, including an array
of diseases.
On the
other hand, the mere brain amyloidosis in Alzheimer's
disease involves several mechanisms and it is unlikely that a single cocktail
of nutrients will provide an optimal outcome.
Over the last decade, large epidemiological studies have shown that kidney stone formers have an increased likelihood
of developing
other conditions such as hypertension, chronic kidney
disease and heart
disease; however, the mechanisms
involved are unknown.
In
other disease areas, the Parkinson's
disease map and the Atlas
of Cancer Signalling Network, have already begun the process
of integrating knowledge about the
involved mechanisms in order to understand the different subtypes
of these
diseases.
«Understanding the principles and mechanisms
involved in neuronal homeostasis may lead to new approaches in the treatment
of these and
other brain disorders like Alzheimer's
disease.»
Because many
of these drugs have already earned FDA approval for use in
other diseases, the processes
of repositioning these drugs for new
diseases is much less
involved and expensive than if drug developers had started fresh.
And could seeds
of other related
diseases involving misfolded proteins be transmitted in a similar way?
Collagen, a structural protein often
involved in scarring and wound healing, is emerging as an important factor in a number
of other diseases, Eliceiri says.
Depression is associated with a multitude
of pathological processes, including inflammation
of the peripheral immune system, a set
of biological structures and processes in the lymph nodes and
other tissues that protect against
disease and abnormalities
involving synapses, the structures that permit neurons to pass an electrical or chemical signal to
other neurons.
«We've shown that there are strong links between damage and
disease in this study, now we're interested in understanding and managing
other potential drivers
of diseases that
involve injury - such as outbreaks
of crown -
of - thorns starfish, cyclones, and recreational activities like anchoring.»
However, because the MHC variants account for less than half the genetic risk
of contracting the
disease,
other genes had to be
involved.
Other medical sequencing projects will use DNA sequencing to: discover new genes that are
involved in common
diseases; identify the genes responsible for dozens
of relatively rare, single - gene (autosomal Mendelian)
diseases; sequence all
of the genes on the X chromosome from affected individuals to identify those
involved in sex - linked
diseases; and survey the range
of variants in genes known to contribute to certain common
diseases.
This sheds light on structural and functional studies
of other ZIP proteins
involved in a variety
of cancers, osteoarthritis and
other serious
diseases.
Parkinson's
disease, obsessive compulsive disorder, attention deficit hyperactivity disorder and many
other movement disorders
involve connections
of this brain region, said Dong, senior author
of the study.
Since neural systems
involved in movement control are tightly interconnected,
disease in one part
of the brain leads to consequential, sometimes compensatory, reactions in
other parts.
«The fact that the mechanism
of action
involves the p38 MAPK enzyme is fortuitous because drugs to combat that pathway are being tested for
other diseases.
Timothy Springer, with colleagues Michael L. Dustin and Charles A. Dinarello, identifies and characterizes adhesion molecules, a class
of cell surface proteins that function in the interactions
of immune cells with
other cells, including antigen - specific recognition and cell trafficking: integrin LFA - 1
involved in cytoskeleton and signaling, and intracellular adhesion molecules (ICAMs), which are binding partners (ligands) for LFA - 1 and are increased in inflammatory and autoimmune
disease.
«It's important not to interpret this study as an argument against vaccination
of our children against flu or any
other disease,» Peter Openshaw, president
of the British Society for Immunology and Professor
of Experimental Medicine at Imperial College London (who wasn't
involved in the study) told the Science Media Centre.
Other possible applications
of the research are in
diseases involving muscle damage, including muscular dystrophy, according to the lab.
These genetic variations were found in regions
of the DNA that were near genes
involved in Parkinson's
disease and
other brain disorders.
They will then examine
other mouse models with mutations
involved in cell - adhesion and extracellular matrix molecules for signs
of RPE
diseases.