Sentences with phrase «of other genes involved»

Myc is a critical gene in governing cell proliferation and survival, activities that it carries out by regulating the expression of other genes involved in cell metabolism.

Not exact matches

Even with the phenotype, perhaps there is a «trade off involved» in that the same underlying genetic sub-scripts serve other purposes, or perhaps the sheer numbers of gene - hormonal permutations mean it will always manifest itself due to pure statistics.

The DNA segments that carry genetic information are called genes, but other DNA sequences have structural purposes, or are involved in regulating the expression of genetic information.

«We've known other people who have looked at genes involved in brain size evolution, tested them out and done the same kinds of experiments we've done and come up dry.»

The gene makes a protein that controls the quantities of other proteins a cell produces, and studies in roundworms suggest that the gene is involved in growth and development throughout life.

The study also found that some of the morphing genes in the python's intestine, notably those in a signaling pathway called WNT, were genes that were involved in intestinal and other cancers.

They add that other genes in the region of the genome around Gp - 9 are probably involved in regulating fire ant social organization as well.

Toshihiro Sassa and Takashi Murayama, the first and second authors of the paper, respectively, say, «we would like to identify the other genes involved in downstream signaling from this calcium channel to understand how the signal leads to aversion to high pH.» Sensing alkaline environments is only the first step; the worm must then quickly react to the stimulus by moving away.

«By greatly narrowing the specific genes involved in social disorders, our findings will help uncover targets for treatment and provide measures by which these and other treatments are successful in alleviating the desperation of autism, anxiety and other disorders,» says Korenberg.

This study showed the two subtypes have different genetic origins and involve a dramatically different number of chromosomal rearrangements, mutations and other gene variations.

Many of the additional 38 missing genes looked like they coded for proteins involved in controlling the activity of other genes.

But other genes were probably also involved, because hominid brain expansion took place in multiple stages over 2 million years, says Ajit Varki, a molecular biologist at the University of California, San Diego.

Studies seeking subtle signs of selection in the DNA of humans and other primates have identified dozens of genes, in particular those involved in host - pathogen interactions, reproduction, sensory systems such as olfaction and taste, and more.

Gene mutations involved in enamel mineralization through the CRAC channels were first seen in people with a type of severe combined immunodeficiency, a disorder in which — among other symptoms — tooth enamel may fall off the teeth within five or six years after birth, and the dentine becomes exposed.

Others are involved in conditions that tend to occur alongside ASD, such as psychiatric disorders and epilepsy, and interestingly, some of the genes are also involved in cancer.

The authors conclude that the study of marine mammals is just the first demonstration of this new evolutionary approach, and is versatile enough to be applied to many other emerging questions concerning key genes involved in the diversity of life.

The study involved extracting Ribonucleic acid or RNA — found in the cells of all living organisms — to develop a transcriptome — the gene readouts in a cell — to examine what occurs during the different developmental stages of the cockroach pregnancy and to explore if those changes hold wider applications for other mammals.

Some of the genes involved help regulate the flow of ions in and out of the cells, particularly nerve cells; others code for so - called heat shock proteins that are typically induced during stress.

He's eager to know whether this same set of genes is involved in social responsiveness of other animals.

«Genes code for the sequence of amino acids in proteins, and some are involved in the regulation of the expression of other genes,» he Genes code for the sequence of amino acids in proteins, and some are involved in the regulation of the expression of other genes,» he genes,» he says.

The research suggests that reducing production of the protein, called myoferlin, affects cancer cells in two primary ways: by changing the activation of many genes involved in metastasis in favor of normal cell behavior, and by altering mechanical properties of cancer cells — including their shape and ability to invade — so they are more likely to remain nested together rather than breaking away to travel to other tissues.

Gene drive is so different from other technologies involving genetic modification that it requires a whole new way of thinking about how to evaluate and regulate it, says Jennifer Kuzma, a natural and social scientist at North Carolina State University (NCSU) in Raleigh who helped organize a February workshop there.

Seemingly unambiguous genetic goals — like trying to make people more intelligent — not only involve millions of genes, raising the specter of easy error, but might involve conditional relationships: For instance, our intelligence might be tied to memory in ways we can't yet decode, so trying to improve one ability might inadvertently impede the other.

But as you said, as an individual eats a high - fat diet or is exposed to other types of environmental exposures, the ability of the liver to adapt involves turning on and turning off certain liver genes to control the liver's activity, and that's mediated through these epigenetic mechanisms that modify the activity of established liver genes.

Glk1 is a transcription factor, meaning it binds to specific regions of DNA and activates genes involved in cell death and other plant immune responses.

The researchers note that while some genes involved in obesity could already have been implicated in other aspects of human health, others could be part of pathways that are not yet understood.

FosB is a transcription factor in the brain which, together with other molecules, is involved in so - called signal transduction (transmission of stimuli to the cells), that is to say conveys genetic information between the cells and also determines whether certain genes are activated or not.

If the genes related to color and the genes involved in this aspect of vision sit near each other on the genome, they are more likely to be inherited together.

When he failed, he devoted his attention to other genes involved in the development of C. elegans.

Basically, the gene makes a molecule involved in preparing other genes for expression, helping to distinguish between regions of genes that should be manufactured and those that are silent genetic filler.

Some of the pinpointed genes are known to be involved in the function of synapses, tiny connectors that allow brain cells to communicate with each other through electrical and chemical signals.

A new study involving roundworms appears to have isolated one gene — a transcriptional factor (or gene that controls the regulation of other genes in the genome)-- that appears to be an essential member of the pathway that translates reduced caloric intake into a longer life span.

The researchers discovered that changes in genes involved in the interbrain (the site of the pineal gland and other endocrine glands), for color vision, hormones and the colorful dewlap that males bob to attract females, may contribute to the formation of boundaries between species.

For his part, Lippman is planning to use mutations in HPAT genes to understand some of the other processes that they're involved in.

Loss of the PBRM1 gene function caused the cancer cells to have increased expression of other genes, including gene pathway known as IL6 / JAK - STAT 3, which are involved in immune system stimulation.

Two of these sites fall within genes: one plays a role in the immune system, and the other is involved in metabolism.

«The old textbook description says that once maleness is determined by a few Y chromosome genes and you have gonads, all other sex differences stem from there,» says geneticist Andrew Clark of Cornell University, who was not involved in either study.

Other characteristic patterns of variants included genes involved in immune system activity and the fat content of breast milk.

Among the other genes she says play a role in thoroughbred performance are peroxisome proliferator - activated receptor - γ coactivator - 1 alpha (PGC - 1α), which is involved in skeletal muscle adaptation to exercise; pyruvate dehydrogenase kinase, isozyme 4 (PDK4), involved in glucose regulation, expression of which increased almost fourfold after sprints; and cytochrome c oxidase subunit 4 isoform 2 (COX 4I2), involved in respiration.

A new genetic analysis reveals that our brawny cousins had a number of distinct genes involved in the buildup of certain types of fat in their brains and other tissues — a trait shared by today's Europeans, but not Asians.

This gene, along with a number of other genes encoding proteins involved in nickel homeostasis, has been acquired a long time ago by the bacterium via horizontal gene transfer.

The other gene codes for an opioid receptor, which, among other things, is involved in appetite, the team reports in the May issue of Molecular Psychiatry.

Dudley's team found that HAR - associated schizophrenia genes are found in regions of the genome that influence other genes expressed in the prefrontal cortex, a brain region just behind the forehead that is involved in higher - order thinking.

However, because the MHC variants account for less than half the genetic risk of contracting the disease, other genes had to be involved.

Whilst such studies provide a reservoir of genes involved in bacterial recognition and degradation in vitro the situation in vivo where hemocytes can interact with other immune cells to optimize immune responses is likely to be more complex.

The dynamics of nucleosome formation and positioning in promoters may, for example, help to understand why some genes are highly expressed, such as those involved in normal or malignant growth, while others, such as stress - induced genes, are only rarely expressed under normal conditions.

Other medical sequencing projects will use DNA sequencing to: discover new genes that are involved in common diseases; identify the genes responsible for dozens of relatively rare, single - gene (autosomal Mendelian) diseases; sequence all of the genes on the X chromosome from affected individuals to identify those involved in sex - linked diseases; and survey the range of variants in genes known to contribute to certain common diseases.

In their comprehensive study, which involved a search of gene activity maps as well as testing of human brain tissue, the researchers identified more than 100 enhancers which were much more active in the brain than in other tissues.

Contact: 508-685-3525; [email protected] Woods Hole, Mass. — Many of the genes involved in natural repair of the injured spinal cord of the lamprey are also active in the repair of the peripheral nervous system in mammals, according to a study by a collaborative group of scientists at the Marine Biological Laboratory (MBL) and other institutions.

NF - κB is transcription factor that, among other functions, turns on genes involved in inflammation and immune response, and can be activated in the presence of pro-inflammatory cytokines.