Sentences with phrase «of other genes known»

This doubles the number of all other genes known on the planet.

ZNF804A also interacts with and modulates expression of other genes known to be associated with schizophrenia.

Not exact matches

We know a lot of what we know about gene mutation and our similarities with other animals precisely because we have been working within this paradigm for which there is a ton of evidence.

If Chad and others argue that naturalistic evolution must be dismissed because we don't know exactly what happened with gene mutation and transmission frequencies during particular periods of rapid change, then how can we accept a replacement argument in which we don't even know what happens at all?

This study led to the discovery of 18 new imprinted genes, validated some known genes and resolved the disputed status of some others to provide a gold standard list of 93 imprinted genes in mouse.

A mushroom whose genes have been edited with molecular scissors known as CRISPR / Cas9 doesn't need to be regulated like other genetically modified crops, the U.S. Department of Agriculture said April 13 in a letter to the mushroom's creator.

«We've known other people who have looked at genes involved in brain size evolution, tested them out and done the same kinds of experiments we've done and come up dry.»

A class of small molecules found in grapes, red wine, olive oil, and other foods extends the life of yeast cells by approximately 70 % and activates genes known to extend life span in laboratory animals.

One area like — now again, all of these areas, you know, have been discovered by others — is molecular - associated biology identifying genes that are important [in] social behavior.

«Professor Hummon and I have been mapping gene expressions for the right versus the left side of the colon, which we now know are different from each other due to the way the colon forms,» said Buechler.

Inherited mutations of the tumour suppressor gene CDKN2A are the strongest known risk factors for familial melanoma and mutations in this gene also increase the risk of other cancers.

This gene is known to be highly active in multiple myeloma and many other cancers, raising the possibility that strategies to shut it down could be effective against a variety of tumors.

«From other studies ***** we know that epigenetic modifications of the DPP4 gene, which are associated with an increased production of the enzyme, have a negative impact on the liver metabolism already in young mice, long before fatty liver disease emerges,» says Baumeier.

«For a long time now, the entire field was collecting data on MYC, LIN41, and other genes and proteins without knowing what most of it meant,» said Yamanaka, who is also director of the Center for iPS Cell Research and Application (CiRA) at Kyoto University, and professor at UC San Francisco.

SIX3 and a related gene, SIX2, with a similar pattern of expression in human beta cells, encode proteins known as transcription factors that control the expression of many other genes in the cell.

The researchers used «bait» proteins from over two dozen known autism genes, fishing in a pool of human DNA for other proteins that would interact with the baits.

Berninger and others have previously shown that Sox2, Ascl1, and other transcription factors — proteins that bind to specific DNA sequences to control the activity of genes — can induce the nonneuronal «support cells» known as glia to turn into neurons.

Suspecting that the other four carried a new Ehrlichia species, the researchers sequenced the bacterial gene in their blood and compared it to a database containing the sequences of known infectious bacteria.

In this research, the group looked at two variants of miR - 21, a microRNA «oncomiR» known to target tumor suppressor genes and which is highly expressed in a number of cancers as well as other proliferative diseases such as psoriasis.

Histones and other proteins, when modified by this process known as acetylation, play critical roles in regulation of gene expression, typically resulting in increased gene expression.

The IL - 15R - alpha gene is expressed in tissues other than muscle, and no one knows the full consequences of turning the gene off.

«We don't know what the time period was between the two divergences, but we do know that half of the genes studied suggest that chimpanzees appear to be closer to humans, while the other half contradict this or are ambiguous.»

If we knew what those functions were, then maybe we'd have a better way of manipulating these cells, so I'd be keen on performing some experiments to explore what these other genes do.

We know that Hox genes encode transcription factors that control the activity of other genes, but we found that digit - innervating motor neurons also express other genes, such as FIGN and CNEP4], and we still don't know the function of any of these other genes.

Dubbed Klosneuviruses, the giant virus contains a more complete set of translation machinery genes than any other virus known to date.

He's eager to know whether this same set of genes is involved in social responsiveness of other animals.

«Now that we know how calcification happens and what the key nodes are, we know what genes to look for that might be mutated in other related forms of cardiovascular disease.»

What we were surprised to find out was that the real differences we could detect in terms of when we did the swap experiments to say which yeast could outperform the other — what we learned was that the GAL1 gene, that the part [of] that, the DNA sequence is outside of the GAL1 gene, it acts as a switch to turn up or turn down GAL1 expression, that had evolved considerably from the ancestral situation; and same for the GAL3.And then what had happened was that each function had been optimized, that GAL3 had sort have been tuned to be sort of a loosely regulated kind of available anytime sensor of galactose and GAL1 had evolved to be an incredibly tightly regulated, in fact, it's the most tightly regulated gene you know of in yeast.

Many of these genes are unique to flowering plants, and many are known to be important for producing the flower as well as other structures and other processes specific to flowering plants.»

There are at least six other genes in that part of the chromosome, and Forejt doesn't yet know which one is a speciation gene.

«Because TIA - 1 is known to suppress COX - 2 expression in other cells, we reasoned that the inactivation of the TIA - 1 gene would increase COX - 2 expression in neurons and, consequently, would increase resistance to acute seizures,» he continues.

A particular form of the gene known as TPCN2, for example, bestows brown hair in modern humans; any other form means hair that's another color.

Nobody knows why an invertebrate should need such a gene, but the fact that its various coding regions are organised in a subtly different way from those of all other known globin genes is forcing a rethink about the evolutionary history of globin genes.

In some cases, the missing pieces can be picked up by comparing the new sequences with known sequences of genes from other species.

The site's newest sections describe the growing number of fly genes known to have close relatives in other animals, including humans — evidence, researchers are discovering, that the animal kingdom is interwoven genetically by its own worldwide web.

Some of the pinpointed genes are known to be involved in the function of synapses, tiny connectors that allow brain cells to communicate with each other through electrical and chemical signals.

Two, JARID2 and JMJD3, are part of a family of genes called the Jumonji family, which are known to influence sex differentiation in other animals.

A team of researchers from DuPont added so - called morphogenic genes — known from basic research to promote the production of embryonic tissue — to the other genes being transformed (in this case to express green fluorescent protein as a marker of transformation).

Professor Michael Lisanti, from The University of Manchester — part of Manchester Cancer Research Centre, said: «We know that high breast density can greatly increase a woman's breast cancer risk as well as other factors such as aging, family history and presence of mutations in genes such as BRCA 1 and BRCA 2.

The Swedish Twin Registry has enabled her to compare identical twins, who share 100 % of their genes, with fraternal twins, whose genetic makeups are no more similar to each other than any pair of siblings.

The hardy, microscopic animals also known as moss piglets and technically called tardigrades have scavenged about 17.5 percent of their genes from other creatures.

«In looking for biofuels microbes in the cow rumen, we found that Prevotella bryantii, a bacterium that is known to efficiently break down (the plant fiber) hemicellulose, gears up production of one gene more than others when it is digesting plant matter,» Cann said.

«A couple of other genes are also evolving rapidly and we know nothing about them,» he says, adding that they may affect the behavior of hemagglutinin.

Researchers have long known that a small fraction of genes are more active in one sex than in the other.

Negotiations with the U.S. company that holds the license for commercialization of the vaccine — which contains a gene for the Ebola surface protein stitched into a livestock pathogen known as vesicular stomatitis virus (VSV)-- have needlessly delayed the start of the trial, Becker and several other scientists tell Science.

Loss of the PBRM1 gene function caused the cancer cells to have increased expression of other genes, including gene pathway known as IL6 / JAK - STAT 3, which are involved in immune system stimulation.

So, for example, at the University of California in San Francisco they are trying to engineer E. coli so that it can detect cancer cells, it can invade tumors, and then once it's inside they can release toxins; and so they are putting in all sorts of genes from other bacteria to assemble this, you know, this sort of synthetic E. coli that could become basically a cancer torpedo.

«We note that there are two subgroups of breast tumors by epigenome: one which we have called Epi - Basal, characterized by loss of epigenetic marks causing breakage of chromosomes and the other that we have called Epi - Luminal B, that presents epigenetic inactivation of genes that should protect us from cancer and these altered cells can no longer do it.»

And this piece of information about RGS1 might become valuable down the line when we know more about other genes, because it might fall into place in the puzzle.»

Still, the role of other shape - keeping genes was up in the air, including two known as mreB and mbl, which resemble the actin gene in eukaryotes.