«The vector used in these studies is one that has already been used in the treatment
of other human diseases so this is a promising approach.»
Not exact matches
Founder and CEO Social Capital LP and Golden State Warriors Owner Chamath Palihapitiya has a mission which is, «To advance humanity by solving the world's hardest problems including the advancement
of human capital, the eradication
of disease, solutions to global climate change, and
other really difficult things that are non obvious.»
Andrew Batholomaeus, a consultant toxicologist at Australia's University
of Canberra and the University
of Queensland, states that «the potential
human health consequences
of discouraging the use
of pyriproxyfen in drinking water storage and
other mosquito - reduction programs is catastrophic with potential deaths and serious
disease from otherwise avoidable malaria, dengue and
other mosquito - borne
diseases numbered in at least the hundreds
of thousands.»
The struggle is against a system
of Corporate Power profiting from hunger to pharmaceuticals for
disease and
other forms
of human wants.
Today the two horrors are becoming antibiotic - resistant, and AIDS, herpes, chlamydia, genital warts,
human papilloma virus, and more than a dozen
other sexually transmitted
diseases, most
of them formerly rare, are ravaging the population.
Stem cells can transform into any
other human cells, so they have immense potential for generating all sorts
of adult cells and thus can be used in research concerning
human degenerative (and
other)
diseases.
With the advances in knowledge that are almost certain to be gained from the
Human Genome Initiative — or, if its critics should win the day and it lose support, from more piecemeal genetic - research — we will know more and - more about genetic factors causally related to health and
disease and to
other important aspects
of life, such as intelligence and emotional states.
All
human beings face death as an inevitable destiny, but those
of us who are crippled by heart
disease or cerebral injury or
other illness are more conscious
of this destiny, particularly as we advance in years.
On the
other hand, the techniques
of postcivilization also offer us the possibility
of a society in which the major sources
of human misery have been eliminated, a society in which there will be no war, poverty, or
disease, and in which a large majority
of human beings will be able to live out their lives in relative freedom from most
of the ills which now oppress a major part
of mankind.
so often they just look at potential markers — but those don't always equate to
diseases)- what was the health
of the those being studied - I'm assuming the test subjects were people, but
other studies done on animal subjects might not be as reliable as those done on
humans.
Human breast milk that is frozen or stored for longer than 48 hours loses a significant amount
of its antioxidant content, making it less able to help infants fight off free radicals that play a role in allowing infections and
other diseases.
However, «The AAP Section on Breastfeeding, American College
of Obstetricians and Gynecologists, American Academy
of Family Physicians, Academy
of Breastfeeding Medicine, World Health Organization, United Nations Children's Fund, and many
other health organizations recommend exclusive breastfeeding for the first 6 months
of life.2, 127 — 130 Exclusive breastfeeding is defined as an infant's consumption
of human milk with no supplementation
of any type (no water, no juice, no nonhuman milk, and no foods) except for vitamins, minerals, and medications.131 Exclusive breastfeeding has been shown to provide improved protection against many
diseases and to increase the likelihood
of continued breastfeeding for at least the first year
of life.
These include the infant with galactosemia, 53,54 the infant whose mother uses illegal drugs, 55 the infant whose mother has untreated active tuberculosis, and the infant in the United States whose mother has been infected with the
human immunodeficiency virus.56, 57 In countries with populations at increased risk for
other infectious
diseases and nutritional deficiencies resulting in infant death, the mortality risks associated with not breastfeeding may outweigh the possible risks
of acquiring
human immunodeficiency virus infection.58 Although most prescribed and over-the-counter medications are safe for the breastfed infant, there are a few medications that mothers may need to take that may make it necessary to interrupt breastfeeding temporarily.
Research in the United States, Canada, Europe, and
other developed countries, among predominantly middle - class populations, provides strong evidence that
human milk feeding decreases the incidence and / or severity
of diarrhea,1 - 5 lower respiratory infection,6 - 9 otitis media,3,10 - 14bacteremia, 15,16 bacterial meningitis, 15,17 botulism, 18 urinary tract infection, 19 and necrotizing enterocolitis.20, 21 There are a number
of studies that show a possible protective effect
of human milk feeding against sudden infant death syndrome,22 - 24insulin - dependent diabetes mellitus,25 - 27 Crohn's
disease, 28,29 ulcerative colitis, 29 lymphoma, 30,31 allergic diseases,32 - 34 and
other chronic digestive diseases.35 - 37 Breastfeeding has also been related to possible enhancement
of cognitive development.38, 39
Excessive and unnecessary use
of the drugs, which are similar to what doctors prescribe for people's ear infections, strep throats and
other illnesses, can lead to super-resistant strains
of bacteria that can cause serious
human diseases that have no cure.
Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis
disease or are
human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number
of other medications until they clear the milk109, 110; mothers who are using drugs
of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from
other breast if clear
of lesions).
Physiologic sleep studies have found that breastfed infants are more easily aroused from sleep than their formula - fed counterparts.247, 248 In addition, breastfeeding results in a decreased incidence
of diarrhea, upper and lower respiratory infections, and
other infectious
diseases249 that are associated with an increased vulnerability to SIDS and provides overall immune system benefits from maternal antibodies and micronutrients in
human milk.250, 251 Exclusive breastfeeding for 6 months has been found to be more protective against infectious
diseases compared with exclusive breastfeeding to 4 months
of age and partial breastfeeding thereafter.249
Capra and
others have evidence that Neandertal versions
of genes make
humans more prone to some
diseases (SN: 3/5/16, p. 18).
The stocks are helping the development
of new countermeasures such as drugs, vaccines and diagnostics in case smallpox should reappear, and may also allow researchers to explore the impact
of smallpox on the
human immune system, providing insights into
other diseases such as AIDS.
Mid-career and more senior Franklin Fellows, both sponsored and self - nominated, work on global issues
of vital importance to the United States, such as the environment; counterterrorism;
human rights; consular matters; international development assistance; HIV / AIDS and
other trans - national
diseases; trade, energy and financial policy; and many
others.
The behavioral tests used here modeled one dimension
of the
disease — an inability to experience pleasure from normal activities — but not
others, such as stress and anxiety, and probably tap into different brain mechanisms in mice than in
humans, he says.
One has not yet been tested in
humans and the
other has not made it through all the mandatory stages
of testing to ensure it is effective at preventing the
disease.
Several species
of mammal, including mice, rats and dogs, are able to sniff out
disease in
humans and
other animals.
One piece
of evidence is the fact that leprosy is a strict
human disease without
other hosts or reservoirs.
Reductions in biodiversity from illegal wildlife trade can have
other substantial negative
human health impacts, including the loss
of potential sources
of pharmaceuticals, experimental models for studying
disease, crop pollination and micronutrients for
humans lacking alternative sources
of protein.
He carried one genetic mutation that in modern
humans raises the risk
of coronary heart
disease by 40 per cent, and two
others that made him prone to a build - up
of fat in the linings
of his arteries.
Preliminary results
of the study were presented at a World Health Organization (WHO) evidence review group meeting, while UNITAID has issued a call for further research into the use
of endectocide class drugs,
of which ivermectin is currently the only one registered for
human use, as new vector control tools in the fight against malaria and
other mosquito borne
disease.
• In
other funding news, the National Institutes
of Health announced a new $ 17 million program to investigate whether extracellular RNA plays an important signaling role in people, and whether it can be harnessed to diagnose and treat
human diseases, Mitch Leslie reports in News & Analysis.
If further studies in
humans prove successful, this research could have broad implications for the prevention
of influenza and, by extension, as an approach for
other infectious
diseases as well.
«Healthy gut bacterial communities are known to benefit immune regulation, metabolism and potentially even the nervous system, so if cholera or
other diarrheal
diseases permanently impact the microbiota, there could be long - term effects on
human health,» explains Regina LaRocque, MD, MPH,
of the Massachusetts General Hospital (MGH) Division
of Infectious
Diseases, co-senior author
of the paper.
Humans might be able to direct gene drives to kill only female mosquitoes (the ones that bite and spread
disease), or render the insects incapable
of carrying malaria, dengue or
other diseases.
The most serious forms
of the
disease are caused by Plasmodium falciparum and Plasmodium vivax, but
other related species (Plasmodium ovale and Plasmodium malariae) can also infect
humans.
After all,
other humans are all potential
disease - carriers, says Valerie Curtis, director
of the Hygiene Centre at the London School
of Hygiene and Tropical Medicine.
Collins and his colleagues exposed one culture
of Escherichia coli — some strains
of which colonize the
human and animal gut;
others of which are notorious for causing
disease outbreaks — to increasing amounts
of an antibiotic over time.
The ease
of transport and the global population mean that
humans are more at risk
of disease than at any
other time in our evolutionary history, Jones says.
The fact that violence can be a symptom
of brain
disease shows not that free will is an illusion, but that free will can be injured just like
other human abilities.
The process enables some viruses to insert their genetic material into the DNA
of healthy
human cells, which can lead to tumors and
other diseases.
Over the course
of a year, a committee led by Green and Leslie Biesecker, chief
of the Genetic
Disease Research Branch at the National
Human Genome Research Institute in Bethesda, Maryland, has been weighing how to handle «incidental findings» that turn up when a genome or exome is sequenced for some
other medical reason.
Unseen by the
human eye, plants interact with many species
of fungi and
other microbes in the surrounding environment, and these exchanges can impact the plant's health and tolerance to stressors such as drought or
disease, as well as the global carbon cycle.
Poinar suggested in the journal American Entomologist that the origins
of this deadly
disease, which today can infect animals ranging from
humans and
other mammals to birds and reptiles, may have begun in an insect such as the biting midge more than 100 million years ago.
Regulatory issues must be addressed before moving to
human studies, Davies said, but the findings published in the August issue
of the Journal
of Clinical Investigation suggest that it may be possible to manipulate the bacterial residents
of the gut — the gut microbiota — to treat obesity and
other chronic
diseases.
But within days skeptics emerged, countering that the tiny remains instead belonged to a small - bodied population
of modern
humans and that LB1 — with her tiny brain and
other odd features — was a
diseased member
of the group.
Last year the National Institutes
of Health announced plans to put some 180 ex-Coulston chimps currently housed at the Alamogordo Primate Facility back in service, to rejoin the roughly 800
other chimps that serve as subjects for studies
of human diseases, therapies and vaccines in the U.S., which is the only country apart from Gabon to maintain chimps for this purpose.
Imagine if genetic
diseases could be removed from the very biological code
of our species — a future in which the likes
of hemophilia, cystic fibrosis or dozens
of other afflictions are simply edited out
of human embryos.
By comparing our genetic make - up to the genomes
of mice, chimps and a menagerie
of other species (rats, chickens, dogs, pufferfish, the microscopic worm Caenorhabditis elegans, the fruit fly Drosophila melanogaster and many bacteria), scientists have learned a great deal about how genes evolve over time, and gained insights into
human diseases.
«Lots
of ideas and efforts have been made to use NSAIDs to treat
human pathologies, including colorectal cancer and
other diseases,» Miller said.
«Understanding the evolution
of malaria parasites in bats and
other animals, and how they fit into the tree
of life, is key to understanding this important
human disease.»
Mutation around the region
of the
human SOX9 gene, which encodes the Sox9 protein, causes campomelic dysplasia, a congenital
disease that is accompanied by skeletal abnormalities and
other conditions.
By pairing a receptor that targets neurons with a molecule that degrades the main component
of Alzheimer's plaques, the biologists were able to substantially dissolve these plaques in mice brains and
human brain tissue, offering a potential mechanism for treating the debilitating
disease, as well as
other conditions that involve either the brain or the eyes.
The
human cell - based
disease model is expected to lead to a better understanding
of these disorders and
other illnesses, Hsiao said.