Male Balb / c mice (6 — 8 weeks) were sensitized on days 1 and 6 via intraperitoneal injection of 0.9 % sterile saline (0.5 ml) or 0.9 % saline containing 10 μg
of ovalbumin and 2 mg of Al (OH) 3.
Ovalbumin elicits a robust inflammatory reaction in the airways characterized by an increased number of total cells and eosinophils in the BAL
of ovalbumin - sensitized mice (Fig. 6B).
One contains the vaccine — for their tests, the researchers used a liquid version
of ovalbumin, a constituent of egg whites.
Not exact matches
They added fluorescently labeled
ovalbumin (FITC - OVA) to the patches to determine the extent
of protein translocation after NIR irradiation on murine skin.
Since we observed robust inhibition
of NFκB in the presence
of RIPK2 inhibitor 1 and a > 70 % recovery
of animals from DSS - induced inflammation injury (Figs. 4 and 6B), we proceeded to explore the ability to resolve lung inflammation using the
ovalbumin challenge model (Kumar et al., 2008).
RIPK2 gene silencing in the airways decreased allergic airway inflammation in an
ovalbumin - mediated mouse model
of asthma (Jun et al., 2013).
Sensitization and challenge with
ovalbumin (OVA) in this model induce accumulation
of inflammatory cells in the BAL that are primarily eosinophils.
(C) In vivo inhibition
of lung inflammation in an
ovalbumin - induced asthma model in mice.
Bromelain Exerts Anti-Inflammatory Effects in an
Ovalbumin - Induced Murine Model
of Allergic Airway Disease.