Sentences with phrase «of oxaloacetate»

After a few days of fasting, or of drastically reduced carbohydrate consumption (below 50 g / day), glucose reserves become insufficient both for normal fat oxidation via the supply of oxaloacetate in the Krebs cycle (which gave origin to the phrase «fat burns in the flame of carbohydrate») and for the supply of glucose to the central nervous system (CNS).4

As I mentioned in the Definitive Guide, dietary protein, along with glucose, is a source of oxaloacetate.

It's the absence of oxaloacetate that inhibits ATP generation via Krebs» cycle and necessitates ketone production.

Not exact matches

This pathway allows glutamine to be converted into a variety of metabolic intermediates such as aspartate, asparagine, citrate and oxaloacetate and pyruvate [103].

Upstream ORFs and ATF4 - binding sites are found in many genes, but for the purposes of this review genes that carry out biosynthesis of non-essential amino acids (ASNS, alanine aminotransferase 2, PSAT, serine hydroxymethyltransferase 2, pyrroline -5-carboxylate reductase and glutamate - oxaloacetate transaminase) and genes encoding amino acid transporters (cat1, ASCT1, ASCT2, SNAT2, SNAT7, LAT1, EAAT5 and xCT) are notably abundant [83,120].

Since oxaloacetate is formed from pyruvate (a metabolite of glucose), a certain level of carbohydrate is required in order to burn fats.

Ketones are produced when there is no longer enough oxaloacetate in the mitochondria of cells to condense with acetyl CoA formed from fatty acids.

But if you look at the recent data on utilising ketones during exercise, giving a small supply of glucose provides some substrate for anapleurosis (i.e. regenerating oxaloacetate) to allow you to use the Acetyl - CoA coming from ketones or beta - oxidation of fats.