Sentences with phrase «of oxidative processes»

Our results suggest a starting point for the prevention of oxidative processes associated with aging.»

The hydrothermal conditions of the experiments, which also mimic early Earth settings (a proximity to volcanic activity and impact craters), released a complex mixture of oxygen - rich compounds, the probable result of oxidative processes that occurred in the parent body.

Not exact matches

Without giving you the ol' biochemisty textbook definition, antioxidants are substances that counteract the process of oxidative stress in the body and oxidative stress is thought to be behind health issues like cancer, heart disease and other chronic disease in our body.

Now 24, he is a first - year graduate student in the department of cellular and structural biology at the University of Texas Health Science Center in San Antonio (UTHSCSA), where he is studying the role of oxidative damage — the wear and tear inflicted upon the cell by toxic molecules called free radicals — in the aging process.

Oxidative stress, inflammation and insulin resistance affect the inner linings of blood vessels, and are associated with the development of atherosclerosis, the disease process that underlies heart disease and causes the arteries to become narrowed.

Drugs that enhance a process called oxidative stress were found to kill rhabdomyosarcoma tumor cells growing in the laboratory and possibly bolstered the effectiveness of chemotherapy against this aggressive tumor of muscle and other soft tissue.

Although reactive oxygen species can damage cells when produced in high amounts, according to a study published online Sept. 5, 2017 by Science Signaling and featured on the journal's cover, these oxidative species are crucial signals that start the process of repairing myofiber.

Taken together, the study's findings demonstrate that FOX01 plays an integral role in two key processes in wound healing: activation of TGF - β1 and protecting the cell against oxidative damage.

Transition metals such as rhodium and palladium (Pd) often catalyze reactions through a pair of processes termed oxidative addition and reductive elimination.

Our work aims to investigate mechanistically the molecular processes through which dysregulation of factors controlling oxidative stress impairs RPE and photoreceptor cell metabolism and their survival in AMD.

More recently, her lab started working on the mechanisms that link oxidative stress and photoreceptor loss and dysfunction, with the goal of identifying ways to target the underlying processes to prevent photoreceptor and RPE loss in dry AMD.

This work aims to investigate, mechanistically, the molecular processes related to dysregulation of factors that normally protect the eye against oxidative stress, thus impairing RPE and photoreceptor cellular metabolism and their survival in AMD.

Protein nitrotyrosine is a marker for inflammatory or oxidative stress processes (characteristic of COPD) and may also indicate endothelial dysfunction (systemic malfunctioning of the inner lining of blood vessels), a common cause of cardiovascular disease.

Review: The role of operating parameters and oxidative damage mechanisms of Advanced Chemical Oxidation Processes in the combat against antibiotic - resistant bacteria and resistance genes present in urban wastewater — I. Michael - Kordatou — Water Research

This DNA becomes damaged in the course of normal cellular processes, and certain forms of mitochondrial DNA damage - to the thirteen genes needed for oxidative phosphorylation - produce malfunctioning mitochondria that can overtake their cells, either by replicating more readily or being more resistant to quality control mechanisms.

Over time however, mutations in these genes occur as a result of constant exposure to reactive oxygen species produced by oxidative phosphorylation, the mitochondrial energy generation process.

Such diseases are believed to be initiated by mutations and rearrangements of the DNA sequence.DNA damage generated by ionising radiation, simple alkylating agents or endogenously hydrolytic and oxidative processes is corrected by the base excision repair (BER) pathway.

oxidation (adj. oxidative) A process that involves one molecule's theft of an electron from another.

Enhanced amyloidogenic processing of APP by the ß - site APP cleaving enzyme (BACE) and the γ - secretase complex and reduced clearance lead to increased intracellular levels of soluble oligomeric Aß, resulting in cellular dysfunction comprising e.g., synaptic failure, mitochondrial dysfunction, enhanced oxidative stress, neurotransmitter and neurotrophin depletion, inflammation, and apoptosis which is reflected in patients as clinical symptoms such as cognitive deficits [2, 3].

Plus, by reversing the process of oxidative stress, a person will have a smaller risk of developing atherosclerosis when they consume chia seeds regularly.

For one thing, the drug may hamper your kidneys» ability to clear out the by - products of your body's healing process, potentially leading to a buildup of oxidative stress.

Iron is useful for participating in lots of different chemical reactions in the body, as part of normal metabolism, but it's also important for caring oxygen to our tissues and oxygen is what we need in a process called oxidative phosphorylation, which gives us energy.

In fact, oxidative stress is so harmful to the body that many experts think of it as a key factor in the aging process itself.1 Caffeine and its catabolic products, theobromine and xanthine, are all capable antioxidants which are extremely useful to the body in fighting oxidative stress.2

«The initial biochemical local sub-cellular damage is due to the entrance of the usually acidic NSAID into the cell via damage of the brush border cell membrane and disruption of the mitochondrial process of oxidative phosphorylation, with consequent ATP deficiency ``

The scientists, medical professionals, and athletes on the ground floor of the keto movement can barely contain their excitement over its power to reliably reduce excess body fat, enhance neurological function, protect against diseases of cognitive decline, and slow the rate of inflammation and oxidative damage that are the essence of the (accelerated) aging process.

The correlation between oxidative stress and cortisol is basically this: to make steroid hormones, so it could be testosterone, estrogen, cortisol, to make steroids hormones actually generates a lot of free radicals in the process.

The combination of these activities helps to minimize the cellular damage and resulting inflammation caused by the various oxidative processes.

Stress resistance has not been assessed however and so the biological relevance of this finding is currently unknown.32 Several IER trials (75 - 85 % ER on restricted days) in overweight / obese populations have reported reductions in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directions

Leukotriene B4 (LTB4) plays an important role in several cellular processes involved in inflammation, including oxidative metabolism, enzyme release and stimulation of neutrophil migration and aggregation.

The key underlying factors influencing one's mood and behavior are the 1) the epigenetic (methylation) influences upon neurotransmitter activity and, 2) nutrition and the ability for key biochemical processes to take place and, 3) oxidative stress, an important indicator of need for nutrient and lifestyle management.

Oxidative stress is harmful to the body at a cellular level, so much so that it is thought to be a central factor in the aging process itself.1 These suppositories contain epigallocatechin -3-gallate (EGCG), known for being one of the most potent catechins present in green tea.2

Remember that oxidative stress is a chain reaction — when a free radical steals an electron from a balanced atom, the chemical makeup of the atom is changed, a process is started, and new one is created.

The study authors concluded that the Mediterranean diet plus CoQ10 «improves oxidative DNA damage in elderly subjects and reduces processes of cellular oxidation.

* It is also known to play a critical role in the body's defense against oxidative processes and is especially helpful for maintenance of healthy aging.

Since, as suggested above, this «collateral damage» involves mitochondrial function and oxidative processes, these other complementary interventions could take the form of other modalities we have successfully used for years to both enhance mitochondrial function and reduce excessive oxidative activity.

Glycated proteins and cellular structures have altered function, increased vulnerability to oxidative damage, and reduced degradation and clearance.6 Slowing the entry of glucose into the brain would delay these processes and possibly give the body's defenses more time to dispose of the AGEs.

According to an article published in the Journal of Clinical and Aesthetic Dermatology, rosacea «is linked through a variety of mechanisms to other processes including UV damage, vascular changes, and oxidative tissue damage.»

Carcinogenesis is a multistep process, and oxidative damage is linked to formation of tumors through several mechanisms (9, 10).

These provide antioxidant and anti-inflammatory protection against oxidative stress caused by free radicals, thereby slowing down the aging process and reducing the risk of chronic diseases such as cancer.

Removing this source of oxidative stress and inflammation is certainly a good beginning to ridding your patients of degenerative disease processes.

This sets off a chain reaction of imbalance and damage at the cellular level referred to as oxidative stress - a condition thought to be a core factor in the aging process itself!

Research has shown that oxidative damage contributes to many diseases including cancer, heart disease, Alzheimer, and most chronic diseases, and accumulation of oxidative damage plays an important role in the aging process.

1 Supporting the body's natural processes for cleansing itself of heavy metals is a great first step to take for limiting accumulations of oxidative stress.

Diseases of old age: Alzheimer's, heart disease, diabetes, dementia and cancer are the result of oxidative stress coming from poor lifestyle, poor diets and mental - emotional stress.Cigarette smoking, excessive alcohol consumption, excess sugar and salt, processed foods containing chemicals create a chemical and heavy metal burden on the body responsible for diseases of old age.It is possible to avoid all the illnesses.

Antioxidants work by significantly slowing or preventing the oxidative — or damage from oxygen — process caused by substances called free radicals that can lead to cell dysfunction and the onset of problems like heart disease and diabetes.

This veg a great source of antioxidants and vitamin C, which help decrease oxidative stress, improving your immunity and delaying the aging process.

Acetyl L Carnitine and Alpha lipoic acid can also prevent any harmful oxidative process in mitochondrial metabolism of penile cells.

Antioxidants work by significantly slowing or preventing the oxidative — or damage from oxygen — process caused by substances called free radicals that can lead to cell dysfunction and the onset of problems like heart disease and diabetes, but also of the inflammation underpinning psoriasis.

PeakO2 ™ contains high levels of beta glucans and L - Ergothioneine, a «master» antioxidant that fights damage from oxidative stress in the body, helping athletes train longer, recover faster, and feel better throughout the process.

Oxidative damage has been implicated in the cause of many diseases such as cancer and Alzheimer's and has an impact on the body's aging process.