Biomedical research scientist with significant basic and translational research experience in the field
of oxidative stress and inflammation driven diseases and preclinical toxicity of drug molecules
Alternate day calorie restriction improves clinical findings and reduces markers
of oxidative stress and inflammation in overweight adults with moderate asthma
The fact that cancer began rising in the vegetable oil group in the last few years of the study — again, despite the heavy rate of smoking and deficient intake of vitamin E in the control group — suggests that the full extent of the ravages
of oxidative stress and inflammation caused by vegetable oils takes at least five years to develop.
The polysaccharides, or polymeric carbohydrate molecules within pumpkin, elicit significant antioxidant and cytoprotective effects, such that pumpkin may aid in ameliorating
some of the oxidative stress and inflammation behind most chronic and degenerative diseases (Song et al., 2013).
Some studies also found that it helped reduce markers
of oxidative stress and inflammation, related to the development of cardiovascular disease 4, 19, 20.
Removing this source
of oxidative stress and inflammation is certainly a good beginning to ridding your patients of degenerative disease processes.
Hodgson, JM et al. 2007 Increased Lean Red Meat Intake Does Not Elevate Markers
of Oxidative Stress and Inflammation in Humans.
«Alternate Day Calorie Restriction Improves Clinical Findings and Reduces Markers
of Oxidative Stress and Inflammation in Overweight Adults with Moderate Asthma,» Free Radical Biology and Medicine, 42 (5), 665 - 674.
In one study, fasting every other day was shown to decrease asthma symptoms and markers
of oxidative stress and inflammation.
Being obese increases the risk of developing heart disease, liver disease and diabetes, most likely because
of oxidative stress and inflammation, Ferreira says.
«Levels of stress hormones, systolic blood pressure and biomarkers
of oxidative stress and inflammation were significantly lower when using real air purifiers,» Kan said.
We also studied biological markers
of oxidative stress and inflammation in relation to milk intake in humans.
Not exact matches
Excessive
inflammation and oxidative stress are risk factors not only for the development
of chronic diseases like type 2 diabetes, but also for the development
of cancers.
The formation
of plaque along our blood vessel walls starts with chronic, excessive
oxidative stress and inflammation.
Because the toxicity is associated with
oxidative stress and inflammation, the study explored antioxidant
and anti-inflammatory effect
of virgin coconut oil (VCO) supplementation in nephrotoxicity induced by MTX in rats.
11) Intermittent Fasting: Going 16 hours between dinner
and breakfast is one
of the best ways to reduce
oxidative stress and inflammation and repair the gut lining.
Given the fact that
oxidative stress and chronic
inflammation are risks factors for cancer, the antioxidant
and anti-inflammatory richness
of cabbage in a healthy
and balanced diet help to keep you at a lower risk for cancer
and other chronic diseases.
It also boasts over 45 different flavonoids, making kale a front - runner against
inflammation and oxidative stress, which can help lower your risk
of cancer.
Its wide array
of nutrients offer antioxidant
and anti-inflammatory protection, combating the two main issues that lead to chronic disease: —
oxidative stress and inflammation.
«The exact mechanism to explain these findings have not yet been entirely elucidated; however, it may be a reflection
of the improvement in
oxidative stress, insulin sensitivity,
inflammation,
and vascular endothelial function
and permeability that may contribute to positive changes in kidney function,» said Dr. Naga Chalasani, senior author
of the Alimentary Pharmacology
and Therapeutics analysis.
Oxidative stress,
inflammation and insulin resistance affect the inner linings
of blood vessels,
and are associated with the development
of atherosclerosis, the disease process that underlies heart disease
and causes the arteries to become narrowed.
«The chemicals produced by cooking meats at high temperatures induce
oxidative stress,
inflammation and insulin resistance in animal studies,
and these pathways may also lead to an elevated risk
of developing high blood pressure,» said Gang Liu, Ph.D., lead author
of the study
and a postdoctoral research fellow in the department
of nutrition at the Harvard T.H. Chan School
of Public Health in Boston.
The
oxidative stress and resulting
inflammation appear to play a role in the development
of atherosclerosis (blocked arteries)
and can make other health conditions worse, especially for people with existing cardiac or lung conditions including asthma.
Such «couch - potato» animals develop a range
of health problems, including insulin resistance, diabetes, high blood pressure, impaired brain function, increased
oxidative stress and inflammation.
But one group that was fed a diet still fairly high in sugar — an amount
of sugar comparable to the Western diet — had significantly higher levels
of inflammation,
oxidative stress and liver fibrosis.
Adding eggs to a salad with a variety
of raw vegetables is an effective method to improve the absorption
of carotenoids, which are fat - soluble nutrients that help reduce
inflammation and oxidative stress, according to research from Purdue University.
«Together, these findings raise the possibility that hippocampal dysfunction in GWI is one
of the adverse outcomes
of persistently elevated
oxidative stress and inflammation at the systemic level,» he added.
The research, published in PLOS ONE, found that several markers
of insulin resistance were increased following sustained exposure (6 - 8 weeks) to hypoxia at high altitude
and that this change was related to increased blood levels
of markers
of inflammation and oxidative stress.
These include lipid lowering; protection from
oxidative stress and inflammation; modification
of growth factors that can promote cancer; inhibition
of nutrient sensing pathways by amino acid restriction
and gut microbiota - mediated production
of metabolites.
Severity
of pancreatitis in obesity may be attributed to increased
oxidative stress, free fatty acid production, fat necrosis
and increased
inflammation [8].
Increased free radical induced
oxidative stress plays a pivotal role in pathogenesis
of many diseases including obesity, T2D
and AP [7, 39 - 43] leading to macromolecular damage (DNA, protein
and lipids),
inflammation, ER
stress and necrosis
of acinar cells [44].
Higher
inflammation and greater
oxidative stress in diabetic women with end - stage renal disease, as well as modifiable gender differences in access to
and modalities
of treatment involved, were identified in some
of these studies partly explaining excess mortality in diabetic women (319 — 322).
Besides lipotoxicity (see section V.N) many other molecular mechanisms are involved, including mitochondrial dysfunction,
oxidative stress, intramyocardial
inflammation, involvement
of the reninangiotensin system, altered insulin signaling or female - specific cardiac glycogen handling as a response to metabolic
stress (308),
and sex - hormone related myocardial calcium handling (309).
Enhanced amyloidogenic processing
of APP by the ß - site APP cleaving enzyme (BACE)
and the γ - secretase complex
and reduced clearance lead to increased intracellular levels
of soluble oligomeric Aß, resulting in cellular dysfunction comprising e.g., synaptic failure, mitochondrial dysfunction, enhanced
oxidative stress, neurotransmitter
and neurotrophin depletion,
inflammation,
and apoptosis which is reflected in patients as clinical symptoms such as cognitive deficits [2, 3].
In addition, fish oil reduces
inflammation and oxidative stress, which are two
of the key contributing factors to insulin resistance
and many serious diseases,
and significantly lowers triglyceride levels, whose presence in the body is associated with high levels
of insulin.
It is largely important to determine if this is the root cause
of the anemia because iron supplementation given during this state
of inflammation can potentially create more damage
and oxidative stress.
Altered metabolism has been closely linked to
oxidative stress and inflammation,
and the use
of antioxidants in nutritional plans has been shown to have a positive influence on this.
It's rich in antioxidants, potent phytonutrient glucosinolates
and contains compounds known as bioflavonoids such as kaempferol which combat
inflammation by cooling the body
and inhibiting the effects
of oxidative stress and weight gain.
Eggplants contain a variety
of important phytonutrients with pronounced antioxidant activity, including phenolic compounds
and flavonoids, which can help prevent
oxidative stress, infection
and inflammation.
Flavonoids are antioxidants that have anti-inflammatory activity,
and inflammation and oxidative stress are characteristic traits
of mental health disorders.
Cigarettes promote
inflammation and oxidative stress, both
of which wreak havoc on our skin
and throughout the body.
Chronic
Inflammation and Oxidative Stress as a major cause
of agerelated diseases
and cancer.
The benefits
of fasting
and calorie restriction also has some nice little research such as: — increased longevity — reducing
oxidative stress — reducing
inflammation — reduce risk
of heart disease — improving neuroendocrine responses — increasing GH secretion — protective effects on heart, lung, brain — decrease in insulin resistance
and other overall disease prevention
and life extension factors....
Not only is glyphosate toxic in
and of itself, causing the
inflammation,
oxidative stress and DNA mutations that can trigger cancer, but — in a sort
of biological «Catch - 22» — the chemical cripples the body's natural defense mechanisms that could otherwise help to detoxify
and neutralize it.
Nieman et al. compared the acute effect
of ingesting bananas versus a 6 % carbohydrate drink on 75 - km cycling performance
and post-exercise
inflammation,
oxidative stress,
and innate immune function using traditional
and metabolomics - based profiling.
The inflammatory effects
of insufficient sleep were quantified in a study32 that deprived participants
of sleep (just under six hours) for one week resulting in expression
of genes associated with
oxidative stress and inflammation.
Raspberry phytonutrients have been shown to play an important role in lowering
oxidative stress, reducing
inflammation,
and thereby altering the development or reproduction
of cancer cells.
Possible ways in which coffee consumption can lower the risk
of stroke include reducing
oxidative stress, weakening subclinical
inflammation,
and improving insulin sensitivity.
The real tragedy is that by putting all our attention on cholesterol, we've virtually ignored the real causes
of heart disease:
inflammation,
oxidative damage,
stress,
and sugar.
This neuro -
inflammation is sometimes called «leaky brain syndrome,»
and this inflammatory
oxidative stress (OS) in the hypothalamus
of the brain is the underlying cause
of brain fog.