Sentences with phrase «of particular genes by»

Registry parts include operators, which are segments of DNA to which repressor proteins bind to prevent gene transcription; cell - cell signaling elements, which produce defined outputs in response to specific chemical inputs; and riboregulators, which can be used to suppress the expression of particular genes by preventing translation of proteins they express.

Not exact matches

Focusing on schizophrenia as a particular exemplar of this change, Luhrmann examines the evolution of psychiatry from psychoanalysis (mental illnesses are caused by emotional conflict) to a purely biomedical scheme (mental illnesses are caused by genes) to present theories, which incorporate both the biological and the social causes (and treatments) of mental illness.

By comparing Bhut Jolokia's RAPD markers with the reference markers, is was possible to determine which species» genes are part of this particular pepper variety.

«Some people are protected from the effects of sleep deprivation by this particular gene variation but, for most of us, sleep loss does something to the brain that simply prevents us from switching gears when circumstances change.»

Most divergence between breeds, however, involves many genes, unwittingly selected by breeders aiming to refine the characteristics of particular lineages.

By combining each mouse's genome, phenome, proteome and metabolome, the scientists were able to identify a particular gene, located on their chromosome 2, and whose presence plays an important role in the development of type 2 diabetes «The mice with a high - fat diet are more or less likely to develop diabetes depending on whether this gene is active or not,» said Evan Williams, LISP PhD student and the article's co-first author.

The authors reproduced this disorder in mice to explore whether mutations in a particular VGSC, encoded by the SCN8A gene, increase the risk of cardiac arrhythmia, which might, in turn, influence susceptibility to SUDEP.

SEATTLE — Some people who have a particular form of a gene that, when mutated, causes Werner's syndrome — a rare disorder characterized by rapid aging in youth — appear to have a relatively low risk of suffering a heart attack.

«My part of it was basically to identify what gene was being activated by a particular effector from the bacteria in order to cause disease,» he said.

And although the rest of Genghis Khan's genome has certainly, if Zerjal and Tyler - Smith are right, made an outsize contribution to the Central Asian gene pool, it has been chopped to bits and mixed in so thoroughly over the centuries by genetic recombination that no one today is likely to have his whole suite of genes for any particular trait.

Similarly, someone who inherits the version of a particular gene that's associated with obesity will be more likely to wind up fat than someone who inherits a normal version, but that tendency can be affected by environmental factors such as how much fattening food is available.

In the animal model, the researchers eliminate some of the stem cells by deleting a particular gene in them.

Kenwrick assesses the likelihood of an inherited cause by studying the family's genetic tree and medical history, interpreting existing pathology or genetic reports from cancer patients in the family, and offering genetic tests if particular genes seem to be the likely culprits.

Springer probed beneath surface appearances by studying five particular genes in dozens of different mammals.

At that point, a particular type of protein called a transcription activator can kick - start the molecular process by which a gene gets turned on.

Genes that lead to the toxic effects of the huntingtin gene may be silenced by these microRNAs, in particular the miR - 10b - 5p microRNA.

«In other words, access to the genes is determined by the host, but usage of particular genes is regulated by the microbes,» Crawford said.

In June, he and his colleague Thaddeus Stappenbeck argued in Nature that all mouse studies should use littermate controls: When studying the activity of a particular gene, breed mice with and without that gene by starting with heterozygous parents.

But it has not been clear until now that the effects of these particular gene variations can vary by race in patients taking clopidogrel after a heart attack.

Ethionamide in particular is activated by the enzyme EthA, but some resistant forms of tuberculosis have developed mutations in the ethA gene, sparing them from the toxic effects of the transformed ethionamide.

By comparing the sequences of these genes in healthy versus anorexic people, the team found that anorexic women consistently had particular sequence variations in two of these three genes.

In biological systems in particular, this scale ‐ free addition of new nodes is likely a consequence of gene duplication (Qian et al, 2001), and is also affected by alternate splicing and posttranslational modification in protein networks (Qian et al, 2001; Bhan et al, 2002; Pastor ‐ Satorras et al, 2003; Vazquez et al, 2003), as well as the variable chemical versatility of the metabolic intermediates in metabolic networks.

In particular, the research identified several genes regulated by methylation in the egg that are involved in cell adhesion and migration — both vital properties for cells of the developing placenta in establishing connections with maternal tissues to support embryo development.

Of particular interest were the N - methyl - D - aspartate receptor (NMDAR) genes, which were further studied by qRT — PCR.

By designing the short pieces of RNA to match one particular gene, the intracellular response will specifically silence the expression of that gene.

This enzyme is produced by a region of DNA (or a gene) called GBA — the same GBA gene associated with a particular form of Parkinson's.

The Haematological Cancer Genetics team, led by George Vassiliou, studies the genes and genetic pathways involved in the development of blood cancers, with a particular emphasis on Acute Myeloid Leukaemia and related malignancies.

Ataluren and amlexanox, work by enabling cells to bypass a particular type of DNA gene change known as a nonsense mutation.

In particular, the International Gene Synthesis Consortium (IGSC), which represents approximately 80 % of the dsDNA synthesis industry, has outlined rigorous screening measures that are followed by its seven member companies.

A research team led by Masashi Yanagisawa, director of the International Institute for Integrative Sleep Medicine (IIIS) at the University of Tsukuba, believes the differing tendencies could stem from mutations of particular genes relating to sleep.

DNA lives in the cell nucleus and consists of thousands of genes, each one holding the code, or «blueprint,» for building a particular protein molecule and thus ensuring a certain cell function performed by that protein.

«This is the plot twist that gives away the story,» says Sharma, because it allows scientists like him to trace the evolutionary and genetic history of this group of animals, united by their loss of a particular gene.

They blow up because Maselko's technology instructs the cell to generate an immense amount of proteins caused by that particular gene — but only when the engineered yeast mate with wild versions.

Treatment of this disease is complicated by its many forms, depending on which particular gene functions incorrectly.

By assessing the incidence of a particular mutation or the frequency at which certain genes / pathways are altered across multiple patients (of the same tumor type), it should be possible to identify key mutations.

Since the discovery was made by a group of 19th century German scientists, we have also learnt that the nature of a particular body tissue is determined by its constituent cells, which are, in turn, determined by which genes are active in their DNA.

Schosserer will be spending two months in the laboratory of Aric Rogers, Ph.D., at the MDI Biological Laboratory's Kathryn W. Davis Center for Regenerative Biology and Medicine studying the role that molecular regulators of gene expression play in longevity — and in particular how these regulators are affected by lower amounts of food or food with lower energy content.

I have often read that scientists have argued that your happiness is largely determined by genes and your state of health at a particular time, including several other factors mostly outside of your control.

Additionally, in no particular order, there were vocal supporters of the Ralph Jones «incongruously great score to «Slumber Party Massacre ``; «Phantasm» «s heavily «Exorcist «- indebted score from Fred Myrow and Malcom Seagrave; Danny Elfman «s channelling of Bernard Herrmann for «Nightbreed ``; Wojciech Kilar «s bombastic, often recycled music for «Bram Stoker's Dracula ``; John Harrison's score for Romero's anthology film «Creepshow ``; Richard Band «s better - than - deserved compositions for the terrible «Troll ``; the great Lalo Schifrin «s score for the original «The Amityville Horror ``; a more recent example in Climax Golden Twins» music for Brad Anderson «s now cultish «Session 9 ``; Pino Donaggio's terrific work with de Palma's «Dressed to Kill ``; Gene Moore's classic church organ scares in «Carnival of Souls ``; and while we've featured Bava fils above, we could easily have found room for his father Mario Bava, probably with the funky original music by Libra for his final film «Shock.»

LAURA *** / **** Image B Sound B - Extras B starring Gene Tierney, Dana Andrews, Vincent Price, Judith Anderson screenplay by Jay Dratler and Samuel Hoffenstein and Betty Reinhardt, based on the novel by Vera Caspary directed by Otto Preminger PINKY * / **** Image C Sound B - Extras A + starring Jeanne Crain, Ethel Barrymore, Ethel Waters, William Lundigan screenplay by Philip Dunne and Dudley Nichols, from a novel by Cid Ricketts Sumner directed by Elia Kazan by Walter Chaw A camp classic of a very particular variety, Otto Preminger's stylish, pedigreed Laura might best be read as a satire of Hitchcock's Rebecca, reuniting that film's Judith Anderson with another late, lamented mistress and acres more scenery to chew.

Consequently, I was quite surprised to run across a paper (1) published in 2006 about a study that was able to substantially reduce in incidence and severity of hip dysplasia in Labradors — not by locating particular genes or implementing strategically - designed breeding programs — but by reducing food consumption.

Doing a genetic test and subsequently eliminating an individual from the breeding population may not be the best strategy, as by targeting a particular allele at one genetic locus for removal from the gene pool of a particular breed, breeders may in fact increase allele frequency of genetic variants on alternative haplotypes at the same, or a different locus, that are recessively deleterious.

As long as the frequency of a gene for a recessive disorder remains low in the population, the particular gene may be passed along for many generations before by chance 2 carriers are mated and affected individuals are born.

I was observing the heat rising from my compost heap this morning, the one inspired by my review of Gene Logsdon's guide to managing manure, when I was struck by a particular insight — what I was actually witnessing was the cumulative body heat of billions upon billions of tiny little beasties.

The heart of the innovation, as I understand it, lies in the choice of a particular and small region of DNA shared by many animals; to say it in technical terms: it's «a 648 base - pair region in the mitochondrial cytochrome c oxidase 1 gene («CO1»).»

Related to this question, recent research suggests that particular polymorphisms, often those linked to risk for pathology, make the individual more susceptible to be influenced by parenting and other experiences.24 - 26 For example, children carrying the 7 - repeat variation of the DRD4 appear to benefit more from interventions directed to prevent behaviour problems than those carrying other variations of the gene.24 Nonetheless, further research is needed on how and to what extent EC skills may be influenced by the interplay between constitution and experience.

From an inclusive fitness perspective, DZ twins and NT siblings have, on average, a probability of 50 % of sharing a particular gene by a common descent.