Sentences with phrase «of patients with»

«Emergency rooms see rising rate of patients with chronic conditions, lower rate of injuries.»

We can not make robust conclusions because the subgroup of patients with negative EGFR was very small, but the hypothesis generated here is that those tumours do not respond well to necitumumab.»

The current study analysed outcomes in the subgroup of patients with EGFR expressing tumours compared to those with no EGFRs.

Motivated by their previous finding of the presence of P - glycoprotein overexpression in the nasal lining of patients with CRS with nasal polyps, the study authors conducted a randomized, double - blind, placebo - controlled clinical trial studying the use of low - dose Verapamil in 18 patients with CRS with nasal polyps.

The researchers suggest that their study demonstrates the potential of these non-toxic therapies to contribute to current cancer treatment regimens and significantly improve the outcome of patients with advanced metastatic cancer.

The ever - growing crowd of misfolded proteins form the aggregates seen in the brains of patients with neurodegenerative disorders such as Parkinson's and Alzheimer's diseases.

There are cases of patients with severe TMD who don't present with migraine,» said Débora Grossi, the lead researcher for the study and principal investigator for the Thematic Project.

The majority of patients with fibromyalgia can see improvement in their symptoms and lead normal lives with the right medications and extensive use of non-drug therapies.»

In the same report, the researchers replicated these findings in an independent validation study in which they found methylation among 9.1 % of patients with high - grade serous cancers versus 4.3 % among controls.

After seeing promising results in phase 1 of the Pediatric Leukemia Adoptive Therapy (PLAT - 02) trial with 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia (ALL) achieving complete initial remission, researchers at Seattle Children's are continuing their quest to improve the experimental therapy and reduce the rate of relapse, which is about 50 percent.

«This finding suggests a novel therapeutic target to decrease invasion of tumor cells in patients and may also provide a novel biomarker that could help predict survival of patients with glioblastoma,» explained Israel.

Assessments of physical functioning, depression, sleep disturbance, and catastrophic thinking were rated important for all groups of patients with cLBP.

After sequencing tissue taken from 19 Taiwanese patients with upper urinary tract cancer, the researchers found that a control group of patients with upper urinary tract cancer but no history of birthwort use did not show the same pattern of mutations.

Recent research shows that high - intensity interval exercise — training for a few minutes at close to the maximum heart rate — is safe and more efficient than moderate exercise for improving exercise capacity in different groups of patients with heart disease.

For the study, Dr. Lakhani and his colleague, Baskaran Sundaram, M.D., obtained 1,007 X-rays of patients with and without active TB.

Shadmehr's team says the difference was not due to a lack of strength in the affected arm of the patients with PD, because the team also tested each arm's ability to apply force in every direction and found that the patients» strength was comparable to that of healthy individuals.

About 15 percent of patients with an upper respiratory tract infection — the type of infection we typically think of as a «common cold» — went on to develop pneumonia, or an infection of the lower respiratory tract.

This study of 27 patients indicates that temsirolimus, an mTOR inhibitor, and HCQ is safe and tolerable, blocks autophagy, and had significant antitumor activity; researchers observed stable disease in 75 percent of those patients with metastatic melanoma.

Because of the large number of patients with A / H1N1 and the limited number of beds, I was given medicine and released from the hospital.

As the number of Americans age 80 and older continues to rise, so does the percentage of patients with acute spinal conditions.

Commenting on the results, Professor Johan Vansteenkiste, Professor of Medicine, Catholic University Leuven, and Chief Oncology Physician, Unit of Respiratory Oncology, University Hospital KU Leuven, Belgium, said: «This study may change current practice for the treatment of patients with advanced NSCLC.

Pembrolizumab is set to become a new option for first line treatment of patients with advanced lung cancer and high PD - L1 expression, according to the results of the phase III KEYNOTE - 024 trial presented at the ESMO 2016 Congress in Copenhagen and published in the New England Journal of Medicine.

They also chose to study a type of K - Ras mutant called G12C (for Glycine - 12 to Cysteine), a K - Ras mutant prevalent in about seven percent of patients with lung cancer.

At least 50 % of patients with Graves» disease, an autoimmune disease that primarily attacks the thyroid gland, develop eye problems including inflammation, discomfort, scarring, and bulging eyes.

Second, we believe the vaccine may be particularly beneficial for a group of patients with the HLA - A2 type, which suggests that as we move forward, there may be advantages in targeting this population,» said John Yu, MD, vice chair of the Department of Neurosurgery, director of surgical neuro - oncology, medical director of the Brain Tumor Center and neurosurgical director of the Gamma Knife Program at Cedars - Sinai.

Adams points out that Cohort A is the first phase II study of an immunotherapy for triple negative breast cancer to be reported and represents the largest cohort of patients with mTNBC treated with immunotherapy to date.

In the group of patients with aggressive, or high risk, prostate cancer, the average number of days from diagnosis to surgery or radiation treatment was 96 days for Caucasian patients, and 105 days for African American patients.

«Because of the vulnerable nature of patients with mental illness, such as their susceptibility for opioid dependency and abuse, this finding warrants urgent attention to determine if the risks associated with such prescribing are balanced with therapeutic benefits,» said study co-author Brian Sites, an anesthesiologist at Dartmouth - Hitchcock Medical Center.

However, a majority of patients with advanced NSCLC worldwide do not have tumors with these mutations (known as wild - type [WT]; no mutation detected within the gene).

The researchers point out that organised trauma care networks rely on correct and prompt identification of patients with serious injury and emergency transport direct to a trauma care centre rather than the local hospital.

«All endpoints of efficacy and tolerability favoured treatment with pembrolizumab, suggesting it should become one standard of care for first line treatment of patients with advanced NSCLC and high PD - L1 expression.

For instance, from the manufacturer's point of view, an «improvement in the safety of health care» and a «better integration of patients with hemophilia into a normal social life» already arise through market entry.

He said: «Information on outcome of patients with cut - off levels higher than in the current analysis would be of interest.

Dr. Fox serves on the steering committee for the Society for Immunotherapy of Cancer - led Immunoscore Taskforce seeking to standardize and validate the staging of patients with cancer.

Their paper, «Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome,» appeared in the online edition of Science on October 8, 2009.

Hadassah University Medical Center claims the world's largest collection of patients with genetic hair diseases, including roughly half the documented cases of papular atrichia, the condition Christiano linked to the hairless gene.

Research published Oct. 1 provides a molecular basis for why 80 percent of patients with longstanding Type 1 diabetes have chronic gastrointestinal symptoms including gastroparesis (delayed emptying of food), irritable bowel syndrome, abdominal distension and fecal incontinence, significantly reducing their quality of life.

We are proud to support this study, which is one of the first of its kind in the UK to investigate the experience of patients with wet AMD receiving anti-VEGF therapy.

An analysis based on disease subtype showed that ibrutinib produced complete or partial responses in 37 percent (14 of 38) of patients with ABC DLBCL but only 5 percent (1 of 20) of patients with GCB DLBCL.

The results from this research suggest that TMS is a safe option for the treatment of patients with MS.

While much remains to be elucidated with this technology, there is great potential to have a dramatic impact on the care of patients with cancer.»

Several years ago, researchers found that 80 percent of patients with uveal melanoma had mutations to GNAQ or GNA11, genes that activate signals in the mitogen - activated protein kinase (MAPK) pathway.

Evidence now indicates that DBS can decrease the number and severity of non motor symptoms of patients with Parkinson's disease (PD) as well, according to a review published in the Journal of Parkinson's Disease.

«Between 15 and 30 percent of patients with hepatitis C genotype 2 or 3 infections do not have a response to interferon therapy and do not have alternate treatment options.»

Deep brain stimulation (DBS) has become a well - recognized non-pharmacologic treatment that improves motor symptoms of patients with early and advanced Parkinson's disease.

Post-transplant steatosis was not associated with worse patient survival within several years, but the long - term survival of patients with significant steatosis tended to be worse.

The new findings suggest a way to stratify the wide range of patients with MDD, which may boost the likelihood of identifying culpable genes.

«This approach may allow tailoring of clinical decisions regarding management of patients with prostate cancer, thus maximizing the benefit and minimizing the harms of therapy,» Roy said.

Researchers have harnessed the CRISPR - Cas9 technology to correct mutations in the blood stem cells of patients with a rare immunodeficiency disorder; the engineered cells successfully engrafted in mice for up to five months.

These impairments can make it difficult for patients to socially adapt and should receive greater attention in the neuropsychological evaluation of patients with memory complaints.