Among children and teens, ALL is the most common, accounting for 75 %
of pediatric leukemia cases.
Methotrexate exposure tied to reduced mental flexibility, planning and other executive function skills in long - term survivors
of pediatric leukemia.
Not exact matches
«This approval will open the floodgates for these kinds
of therapy to be used in many different
leukemias, lymphomas, solid tumors, myelomas,» Dr. Prakash Satwani, a
pediatric hematologist - oncologist at Columbia University Medical Center, told Business Insider.
Excluding type 2 diabetes (because
of insufficient data), we conducted a cost analysis for all
pediatric diseases for which the Agency for Healthcare Research and Quality reported risk ratios that favored breastfeeding: necrotizing enterocolitis, otitis media, gastroenteritis, hospitalization for lower respiratory tract infections, atopic dermatitis, sudden infant death syndrome, childhood asthma, childhood
leukemia, type 1 diabetes mellitus, and childhood obesity.
«I am calling upon him to take those donations out
of his $ 27 million campaign coffer and donate them to a worthy institution that treats children with life - threatening allergies who can't afford EpiPens or with
pediatric cancers like
leukemia and Hodgkin's who are suffering because
of generic drug shortages that he causes,» Long said in a statement.
St. Jude Children's Research Hospital leads study showing that a drug withdrawn from the market in 2010 may enhance the effectiveness
of bone marrow transplants for select
pediatric leukemia patients
These common chemotherapy drugs are used to treat a wide variety
of pediatric cancers, including
leukemias and cancers
of the eye and nerves.
Researchers studying two generations
of a family affected by
pediatric acute lymphoblastic
leukemia (ALL) have identified an inherited variation in the ETV6 gene that is associated with an increased risk
of developing the disease.
«This condition is one
of the main reasons that many bone marrow transplant patients endure long hospital stays after their diseases are cured,» said Kean, who wears a bracelet around her badge from a
pediatric patient cured
of leukemia one year ago, but is still in the hospital due to complications from GVHD.
Those findings are among results
of six studies
of investigational chimeric antigen receptor (CAR) T cells for both adult and
pediatric leukemias, adult lymphomas, and ovarian cancer which will be presented during the 2016 American Society
of Clinical Oncology Annual Meeting.
Seattle Childrens» press release says that Kean wears a bracelet around her badge from a
pediatric patient cured
of leukemia one year ago, but who is still in the hospital due to complications from graft - vs - host.
[3]-RRB- However, the presence
of the Philadelphia (Ph) chromosome is not sufficiently specific to diagnose CML, since it is also found in acute lymphoblastic
leukemia [4](aka ALL, 25 — 30 %
of adult cases and 2 — 10 %
of pediatric cases) and occasionally in acute myelogenous
leukemia (AML).
Removal
of a fifth course
of chemotherapy containing cytarabine resulted in worse overall survival and disease - free survival in
pediatric patients with low - risk acute myeloid
leukemia (AML), according to the results (abstract 10515)
of a pooled analysis
of two Children's Oncology Group (COG) trials presented at the 2017 American Society
of Clinical Oncology (ASCO) Annual Meeting, held June 2 — 6 in Chicago.
The use
of minimal residual disease (MRD) provided a more objective measure
of induction failure in patients with
pediatric acute lymphoblastic
leukemia (ALL) than did morphology, according to the results
of a study published recently in the Journal
of Clinical Oncology.
Researchers reveal genetic secrets
of a high - risk
pediatric leukemia called Ph - ALL, and find treatment potential in the drug ruxolitinib.
«In our research project on
pediatric leukemia we plan to use Gemcode to define the exact chromosomal breakpoints
of large scale chromosomal rearrangements and repetitive sequences that are typical for leukemic cells, but are difficult to characterize in short sequence reads,» said Professor Ann - Christine Syvänen, who leads the Molecular Medicine group.
A phase I / II trial
of genetically modified T cells directed against CD19 for
pediatric and young adult patients with relapsed / refractory CD19 +
leukemia (NCT02028455).
Whole genome and whole transcriptome sequencing
of 31
pediatric Asian patients with T - cell acute lymphoblastic
leukemia found that about 10 percent had the same alteration in a non-coding region
of DNA.
Arsenic trioxide (ATO) consolidation was well tolerated in
pediatric patients with acute promyelocytic
leukemia (APL) and allowed for significant reductions in cumulative anthracycline doses, according to the results
of the Children's Oncology Group AAML0631 trial published in the Journal
of Clinical Oncology.
DATE: April 3 TIME: 4:05 p.m. LOCATION: Room 204, Level 2, Washington Convention Center TITLE: Comparison
of somatic alterations in the genome and transcriptome
of 1,705
pediatric leukemia and solid tumors: a report from the Children's Oncology Group (COG)- NCI TARGET Project ABSTRACT: 3004
He's studying how tumor heterogeneity affects treatment and the role
of microRNAs in
pediatric cancers and
leukemia.
In January, TGI and its collaborators published three Nature papers that came online the same day: one on the genetic basis
of an aggressive
pediatric leukemia, another on genomic and epigenetic analyses
of childhood retinoblastoma, and a third on tumor evolution in relapsed AML.
«This generous funding from ASH allows me to expand upon our exciting new findings regarding the genetic basis
of pediatric acute myeloid
leukemia and also provides essential support as I launch my independent career,» Maxson said.
A phase I / II trial
of KTE - C19 (anti-CD19 CAR T cells) for
pediatric and adolescent subjects with relapsed / refractory B - precursor acute lymphoblastic
leukemia -LRB-
Study 2, led by researchers in the U.S., analyzed the genomes and transcriptomes
of 1,699
pediatric leukemias and solid tumors representing six histotypes.
Shaw PJ, Kan F, Woo Ahn K, Spellman SR, Aljurf M, Ayas M, Burke M, Cairo MS, Chen AR, Davies SM, Frangoul H, Gajewski J, Gale RP, Godder K, Hale GA, Heemskerk MB, Horan J, Kamani N, Kasow KA, Chan KW, Lee SJ, Leung WH, Lewis VA, Miklos D, Oudshoorn M, Petersdorf EW, Ringdén O, Sanders J, Schultz KR, Seber A, Setterholm M, Wall DA, Yu L, Pulsipher MA.Outcomes
of pediatric bone marrow transplantation for
leukemia and myelodysplasia using matched sibling, mismatched related, or matched unrelated donors.
Changes in an epigenetic mechanism that turns expression
of genes on and off may be as important as genetic alterations in causing
pediatric acute lymphoblastic
leukemia (ALL), according to a study led by scientists at St. Jude Children's Research Hospital and published in the June 10 online edition
of the Journal
of Clinical Investigation.
UT Southwestern Medical Center, in partnership with Children's Health, which is located on the same Dallas campus, has an excellent team
of pediatric oncologists who treat
pediatric blood cancers such as
leukemia and lymphoma with the latest techniques.
Our own Naomi Winick, M.D., Professor
of Pediatrics, has held several leadership positions with COG and is involved in clinical trials for
pediatric leukemia.
Our primary mission is to seek out and support experts and institutions dedicated to enhancing and improving the lives
of people afflicted by mesothelioma,
pediatric diabetes and
pediatric leukemia.
[jounal] Best, M. / 2001 / Parental distress during
pediatric leukemia and posttraumatic stress symptoms after treatment ends / Journal
of Pediatric Psychology 26 (5): 299 ~ 307