By examining the brains of these mice, the researchers observed a substantial decrease in inhibitory CA2 neurons, as compared to a control group of normal, healthy mice — a change remarkably similar to that previously observed in postmortem
examinations of people with schizophrenia.
A new Duke University study in mice links three previous and, until now, apparently unrelated hypotheses about the causes of schizophrenia, a debilitating mental disorder appearing in late adolescence that affects how people think, act and perceive reality.The brains
of people with the schizophrenia show various abnormalities, including faulty neural connections or an imbalance of certain brain chemicals.
Danielle A. Schlosser, PhD, Assistant Professor, Department of Psychiatry; Director of the Digital Health Core in the Department of Psychiatry, and Director of the NIH - funded Digital Research and Interventions for Volitional Enhancement (DRIVE) lab at UCSF Dr. Schlosser's research program's goal is to design, develop, and investigate neuroscience - informed digital health solutions to improve the
lives of people with schizophrenia and depression.
Paul Corry, Director of Public Affairs, said: «Hundreds of
thousands of people with schizophrenia still aren't getting treatments like psychological therapies, even though the Government's own watchdog has said they work and are value for money.
- Less than a
third of people with schizophrenia are given a choice about which anti-psychotic drug they are treated with, NICE guidelines specify this choice must be given
After studying astronomy and physics at the University of Southern California, she worked in the Laboratory of Neuro Imaging at the University of California, Los Angeles, studying the brain
structure of people with schizophrenia.
Researchers who have sifted through medical
records of people with schizophrenia from before the disease struck, or medical records of their children, recognize subtle signs even earlier.
One is the «spine pruning theory,» supported by the observation that the frontal brain
regions of people with schizophrenia have fewer dendritic spines, the tentacles on the receiving ends of neurons that process signals from other cells.
More than 50 per cent
of people with schizophrenia experience impaired insight into their illness, which is a key reason they refuse medication or don't seek treatment, says Dr. Philip Gerretsen, Clinician - Scientist in the Campbell Family Mental Health Research Institute at CAMH.
Compared with controls, there was a 1.1-fold increase in L1 in the
tissue of people with schizophrenia, as well as slightly less elevated levels in people with other mental disorders such as major depression, the team reports today in Neuron.
Bowen introduced family systems theory in the late 1960s after years of research into the family
patterns of people with schizophrenia who were receiving treatment and the patterns of his own family of origin.
A team of researchers from Universiti Teknologi Mara and Universiti Sains Malaysia developed a two - stage process to screen two groups of people: at - risk
relatives of people with schizophrenia and a corresponding sample from the general population.
The molecules produced during gluten digestion include exorphins, which have also been found in the spinal
fluid of people with schizophrenia and autism, and are thought to worsen the symptoms of these neurological diseases.
One abnormality that researchers have observed in functional magnetic resonance imaging scans of the
brains of people with schizophrenia is an unusually low level of activity from a specific group of neurons near the brain stem.
THE brains of monkeys whose mothers had flu while pregnant resemble
those of people with schizophrenia.
By injecting a dye that labels active cells and using a PET scanner, Bloomfield's team compared the activity of these people's microglial cells with
those of people with schizophrenia, as well as healthy people.
The offspring later exhibited abnormal behavior, including disturbances in social interaction and behaviors similar to
those of people with schizophrenia.
The brains of monkeys whose mothers had flu while pregnant resemble those of people with schizophrenia
There is also increasing research suggesting that Animal - Assisted Therapy can contribute to the improvement in general well - being
of people with schizophrenia.
Positive and negative symptom behaviors and caregiver burden in the relatives of persons with schizophrenia