Sentences with phrase «of pharmaceutical compounds»

Coral reefs are a valuable source of pharmaceutical compounds.

Cells have become essential in modern medicine as therapies, vehicles for producing high ‑ value therapeutics, and tools for high ‑ throughput screening of pharmaceutical compounds.

Toxicity assessment of pharmaceutical compounds on mixed culture from activated sludge using respirometric technique: The role of microbial community structure — I.A. Vasiliadou, Science of The Total Environment

«We have identified a number of pharmaceutical compounds that selectively inhibit — in different experimental models — the mitochondrial enzyme responsible for the tumour growth, thus limiting fat synthesis and without harming normal cells.»

Not exact matches

Founded in 2010, Vet's First Choice provides FDA - and EPA - approved pharmaceuticals, therapeutic diets, and compounded medications to pet owners on behalf of veterinary practices.

Assuming that the patented compound even makes it to the market, the statement that they only have a few years of exclusivity is definitely true — the market exclusivity for pharmaceuticals is almost always less than half of the patent exclusivity.

The global market for pharmaceutical contract manufacturing, contract research and contract packaging will grow from $ 136.4 billion in 2017 to $ 197.0 billion by 2022 with a compound annual growth rate (CAGR) of 7.6 % for the period of 2017 - 2022.

Indenes are valuable building blocks of a variety of natural products, pharmaceuticals and other bio-active compounds.

In addition to the performance of studies we also advise many pharmaceutical companies about the early development of their new compounds.

In contrast, preparation of more elaborate phosphorus compounds used in chemical catalysis, pharmaceutical, and battery applications requires laborious generation and chlorination of elemental phosphorus.

All studies that make use of chemical compounds (including pharmaceutical research) must disclose the full structures of those compounds, including stereochemistry if known.

Instead of systematically testing the effects of known compounds — the pharmaceutical industry's basic model for more than a century — scientists can now investigate backward, combing through genomic data to find links between specific genotypes and diseases and then screening drug data to identify therapeutic candidates.

That's because researchers have tailored a 3D printer to synthesize pharmaceuticals and other chemicals from simple, widely available starting compounds fed into a series of water bottle — size reactors.

It is the goal of many pharmaceutical and food manufacturers to identify compounds that either block or alter bitter perception, to create a more palatable product.

Two years ago the pharmaceutical giant GlaxoSmithKline purchased Sirtris for $ 720 million, and by August of last year The New York Times was speculating that compounds capable of activating sirtuin genes were now the leading candidates for what the newspaper called «the ultimate free lunch... a drug that tricks the body into thinking it is on [a calorie - restricted] diet.»

A 2013 joint report from epilepsy research organizations explained that «because the marketplace is already awash with [antiseizure drugs], many pharmaceutical companies now refrain from the expensive enterprise of developing new compounds.»

«If a cosmetics company wants to add a new fragrance to its products or a pharmaceutical company needs to change the active ingredients of a drug, they need to add new chemical compounds,» Grier explains.

In some cases these research opportunities arose from a joint venture between BPRU and a pharmaceutical company in the interest of furthering research, such as testing the abuse liability of a novel compound.

AquaPharm aims to find novel medicinal compounds from a variety of marine sources and licence them to pharmaceutical companies for development.

So, if you are a chemist and like simulations — why not try using your knowledge and working in a young start - up, developing tools which will be used for «intelligent» discovery of new pharmaceutical compounds?

Kelly M. Standifer, professor and chair of pharmaceutical sciences at the University of Oklahoma, points out that the researchers tested the compounds» potency in nonneuronal cells forced to express the receptors.

A specially designed chiral catalyst is used to oxidize hydrocarbons into multifunctional compounds that are obtained in high purity and are readily converted into an assortment of molecules that will streamline the synthesis of future pharmaceutical drugs,» said Dr. Leila Bayeh, a former graduate student and lead author of the study.

Deuterium - and tritium - labeled pharmaceutical compounds are pivotal diagnostic tools in drug discovery research, providing vital information about the biological fate of drugs and drug metabolites.

«It's a large amount of pharmaceuticals that we [wastewater treatment plant researchers] look at, it's not a trend that the plants generate higher compound concentrations,» she said.

About the size of a fridge, the mini-factory contains all the parts needed to control and monitor the creation and purification of pharmaceutical - grade compounds (drug - making side of system shown above).

The system also will allow scientists to test millions of compounds in the environment and new pharmaceuticals to understand how they affect the reproductive system and many other organs in the body.

Typically, pharmaceutical scientists start the discovery process by «screening» large libraries of chemical compounds in search of one or a few that might treat disease.

Palladium catalysts are used to form an array of chemical compounds in pharmaceuticals, plastics, agrochemicals, and many other industries.

Crystalline suspensions are attractive formulations to store and administer active pharmaceutical compounds because of their long - term shelf life, low solvent viscosity, and slow dissolution rate.

Their results confirmed that wastewater plants are important sources of pharmaceuticals, but they also demonstrated that these compounds are common in streams that aren't fed by wastewater plants.

But this also provides ample time for chlorine to interact with pharmaceuticals that may be in the water, encouraging development of new antibiotic compounds.

«This finding opens up for new possibilities to stabilise the vast number of amorphous compounds in the R&D pipe - line of big pharmaceutical companies», says Maria Strömme, Professor of Nanotechnology at Uppsala University.

For example, the best national pharmaceutical companies are starting to invest in the validation of plant - derived medicines in an attempt to lay claim to new medicines and compete with the conventional imported compounds, which make up over 70 % of the Brazilian market.

Eng's 1996 conference presentation on a compound in Gila monster venom that affects insulin production caught the attention of biotechnology company Amylin Pharmaceuticals.

The same selective process should also be applied to the recovery of high - value compounds in a chemical or pharmaceutical production plant, where they might otherwise be wasted, Su says.

Now Abbott Laboratories, Bristol - Myers Squibb, GlaxoSmithKline, Sanofi, and Janssen Pharmaceuticals have signed on, bringing the number of compounds to 58.

Those were developed, in part, as a byproduct of previous alliances in which pharmaceutical companies payed for rights to develop would - be drugs discovered at Scripps, as well as through the more traditional approach of licensing early - stage compounds to startup companies that then raise money to develop them further.

There is considerable uncertainty surrounding emerging contaminants in aquatic ecosystems and groundwater, and a recent Penn State study of compounds from pharmaceuticals and personal care products didn't add much clarity.

However, crops that contain pharmaceutical and industrial compounds, many of which are in field trials, do raise concern, says Norman Ellstrand of the University of California, Riverside.

It is generally thought that these compounds have reached the aquatic environment for as long as they have been commercially used, but only during the last decade or so has environmental research been widely conducted and concerns over the effects of pharmaceuticals in water bodies been raised.

Chemists at The University of Texas at Arlington have devised a safer, more environmentally friendly, less expensive and more efficient water - based system for the synthesis of organic compounds typically used in pharmaceuticals, agrochemicals, cosmetics, plastics, textiles and household chemicals.

Rather than remaining unused on the shelf of a pharmaceutical company or academic laboratory, drug compounds become available for other uses.

Drug companies have shown an increasing interest in incorporating CF3 compounds — which contain carbon and fluorine — in a range of pharmaceuticals.

That's part of the reason that most drugs that work in animals don't work in people — only 11 % of oncology compounds that show promise in mice are ever approved for humans — despite billions of dollars spent by pharmaceutical and biotech companies.

It identifies and quantifies the various compounds present in a pharmaceutical product, in a fifth of the time it takes governmental services to do the same job.

PBPK modeling is used in pharmaceutical research and development and in health risk assessment to predict the absorption, distribution, metabolism and excretion of a compound in humans and other animal species.

We established formal partnerships with major pharmaceutical and biotechnology companies to develop compounds or identify targets that enhance interneuron function or restore brain rhythms in models of AD and epilepsy.

This investigation also determines the feasibility of developing improved pharmaceuticals in microgravity using a new method to test the metabolic impacts of drug compounds.

These risks and uncertainties include, among others, those relating to our ability to obtain financing and to form collaborative relationships, uncertainty regarding potential future deterioration in the market for auction rate securities which could result in additional permanent impairment charges, our ability to develop and market diagnostic products, the level of third party reimbursement for our products, risks related to preclinical and clinical development of pharmaceutical products, including the identification of compounds and the completion of clinical trials, the effect of government regulation and the regulatory approval processes, market acceptance, our ability to obtain and protect intellectual property rights for our products, dependence on collaborative relationships, the effect of competitive products, industry trends and other risks identified in deCODE's filings with the Securities and Exchange Commission, including, without limitation, the risk factors identified in our most recent Annual Report on Form 10 - K and any updates to those risk factors filed from time to time in our Quarterly Reports on Form 10 - Q or Current Reports on Form 8 - K.

A: At the time, ideas were beginning to form about which drug compounds to test — the first gene for ALS had been identified two years earlier — but ALS wasn't grabbing the attention of the pharmaceutical industry.