For example, she studied brain activity and speech in a group of teenagers before, and three years after they entered high - school, and found music training in school significantly improved the auditory processing
of phenomes (speech sounds) and had lasting effects on language skills.
Not exact matches
By combining each mouse's genome,
phenome, proteome and metabolome, the scientists were able to identify a particular gene, located on their chromosome 2, and whose presence plays an important role in the development
of type 2 diabetes «The mice with a high - fat diet are more or less likely to develop diabetes depending on whether this gene is active or not,» said Evan Williams, LISP PhD student and the article's co-first author.
In Lausanne, the researchers carried out a detailed study
of the genome and the «
phenome» (the set
of all phenotypes or clinical features)
of a family
of mice composed by 183 members.
I haven't, so I am allowed into the lab's remarkable inner sanctum — the
Phenome Room, a small windowless space the size
of a studio apartment.
By going gene hunting in the
Phenome Room, Jackson Laboratory scientists hope to steer their colleagues away from the search for single genes in favor
of hunting for gene networks.
By now, the BXD community has gathered around 300 million phenotype data points from these animals, generating by far the largest coherent «
phenome» (a set
of all phenotypes expressed in an organism) for any animal experimental cohort.
The institute hosts one
of the two nodes
of the European Genome -
phenome Archive (EGA).
The CNAG - CRG plays a central role in the RD - Connect EU funded project through the development and hosting
of the RD - Connect Genome -
Phenome Analysis Platform.
Thanks to recent advances in high - throughput phenotyping, the size and variety
of the BXD
phenome has increased exponentially since 2010, to ~ 5,000 quantitative clinical phenotypes as
of December 2016 (Figure 2, detailed list could be downloaded here).
These webtools make use
of the multilayered datasets from the BXD mouse population to expedite in silico gene function prediction through a series
of integrative and complimentary systems analytical approaches, including (expression - based)
phenome - wide association, transcriptome - / proteome - wide association, and (reverse --RRB- mediation analysis.
The webtools make use
of the multilayered datasets from the BXD mouse population to expedite in silico gene function prediction through a series
of integrative and complimentary systems analytical approaches, including (expression - based)
phenome - wide association, transcriptome - / proteome - wide association, and (reverse --RRB- mediation analysis (Figure 1 - 2).
These include variant analysis and annotation tools as well as therapeutic prediction tools and gene - drug interaction resources, many
of which are integrated in the Genome -
Phenome Analysis Platform.
335/10: 30 DNA.Land: A community - wide platform to collect millions
of genomes -
phenomes.
131/5: 00
Phenome - wide association study provides biologic insights into the etiology
of age - related macular degeneration.
To address this challenge, the International Mouse Phenotyping Consortium is creating a genome - and
phenome - wide catalog
of gene function by characterizing new knockout - mouse strains across diverse biological systems through a broad set
of standardized phenotyping tests.
Thursday, Oct. 19, 5:45 - 6:15 p.m., Room 330C, South Building Invited Presentation: Assessing the
phenome - wide consequences
of genetically regulated molecular traits H. Im, University
of Chicago, et al
The exhibition explores the psychological and emotional impact
of artworks that, through concept or formal material qualities, hint at larger, elemental
phenome