Sentences with phrase «of pigmentary»

We have to be absolutely sure that the Goldens we think are clear of pigmentary uveitis truly are clear as we start screening genes.

The cause of pigmentary keratopathy is multifactorial.

Fossil specimens of adult macrolepidopterans often exhibit light - and dark - toned areas on their wings [14] and can retain ultrastructural details of their scales [15]; preservation of pigmentary or structural colors has not been reported.

(2009) Structural Persistence of the Retinal Ganglion Cell Projection in the DBA / 2J Mouse Model of Pigmentary Glaucoma (Investigative Ophthalmology & Visual Science, 50: ARVO E-Abstract 2777).

(2008) Age - dependent changes in morphologically identified glial cell populations in the optic nerve of the DBA / 2J mouse model of pigmentary glaucoma (Investigative Ophthalmology & Visual Science, 49: ARVO E-Abstract 3693).

(2008) Early transport deficits and distal axonopathy in the DBA / 2J mouse model of pigmentary glaucoma (Investigative Ophthalmology & Visual Science, 49: ARVO E-Abstract 3664).

«This is a very important discovery that will guide future research efforts to explore the interactions of these pigmentary genes with other genetic and environmental risk factors in cancers not linked to sun exposure, such as eye melanoma.

Not exact matches

However, it will take more research to determine whether other forms of the disease, like normal tension, acute, pigmentary, and trauma - related glaucoma, could also benefit from these encouraging findings.

Structural eye anomalies (in particular, microphthalmia and coloboma), cataracts, intraocular calcifications, and posterior ocular findings have been reported in infants with presumed and laboratory - confirmed prenatal ZIKV infection; however, posterior findings have been the most prevalent.21,25,28,33,35,36,41 - 43 Case series report chorioretinal atrophy, focal pigmentary mottling of the retina, and optic nerve atrophy / anomalies.28, 34,37,41 - 43,55 Series of 20 or more infants with presumed ZIKV - associated microcephaly report ocular findings in 24 % to 55 %.28, 33,42 In one study, testing for ZIKV IgM was performed in 24 of 40 infants (60 %) with microcephaly and the results were positive in the cerebrospinal fluid in 100 % of those tested.42 The proportion of infants with ocular lesions did not differ in those with and without testing.42 In that series, first trimester maternal infection and smaller head circumference significantly correlated with the presence of abnormal ocular findings.42

Although many of the components of this syndrome, such as cognitive, sensory, and motor disabilities, are shared by other congenital infections, 5 features differentiate CZS from other congenital infections: (1) severe microcephaly with partially collapsed skull; (2) thin cerebral cortices with subcortical calcifications; (3) macular scarring and focal pigmentary retinal mottling; (4) congenital contractures; and (5) marked early hypertonia with symptoms of extrapyramidal involvement (Table).

Pigmentation and the pigment cell form an ideal system for genetic analysis of a developmental system, since pigmentary mutations are readily detected and most often are not lethal.

These numerous pigmentary mutations, individually and in appropriate combinations, enable the rigorous evaluation of mutations at the organism, organ and tissue levels, and the assessment of genic interactions.

Pigmentary Uveitis (PU) or Pigmentary Cystic Glaucoma (PCG) is a bilateral inherited disease of Golden Retrievers.

Pigmentary keratopathy / keratitis in the dog is due to pigment migration onto the cornea and is a frequent cause of blindness in the Pug, Shih Tzu and Pekingese.

More severe cases of GVIID and GIID must be differentiated from other inflammatory diseases where extensive alopecia and pigmentary changes are seen.

There has been a great deal of discussion regarding pigmentary uveitis since it was first described as a disease of Golden Retrievers (Sapienza et al, 2000).

Clinical features shared by all 5 subgroups of canine ischemic dermatopathy given above include alopecia with crusting and post-inflammatory, mottled pigmentary change.

Golden Retriever Pigmentary Uveitis (GRPU) was first described and published in 1996 within the American College of Veterinary Ophthalmologists Genetic Committee report of «Ocular Disorders Presumed to be Inherited in Purebred Dogs».

For more information about pigmentary uveitis, please see the Health Section of the GRCA website www.grca.org.

Pigmentary Uveitis (PU) is a disease of the eye, it seems to be found at around age 8, but there are many cases found much earlier (2) and some much later.

Breed health concerns may include progressive retinal atrophy, pyloric stenosis, sebaceous gland tumors, keratocanthoma, hydrocephalus, intervertebral disc disease, entropion (usually lower lids), distichiasis, ectopic cilia, caruncular trichiasis, keratoconjunctivitis sicca («dry eye»), prolapse of the gland of the nictitating membrane («cherry eye»), refractory corneal ulceration and pigmentary keratitis and urolithiasis (calcium oxalate, struvite, silica).

Dr. Rachel Keller immediately diagnosed Piper with pigmentary uveitis in both eyes, a condition common to golden retrievers, in which an inflammation develops and may block the normal drainage of fluids from the eye, resulting in higher than normal pressure within the eye, or glaucoma.

Please see «Pigmentary Uveitis Letter to Owners» on the Health Section of the GRCA website www.grca.org for more information about this disease, including recommendations to help reduce the risks of the most significant health consequences.

An eye disease called pigmentary uveitis is of emerging concern in the breed, and while it is believed to have a genetic basis, at this time there are no satisfactory tools that breeders can use to be certain to avoid producing affected puppies.