Symptoms of Bladder Cancer: • Blood in the urine • Straining or pain during urination • Urinating often • Incontinence • Fatigue • Bone tenderness • Pain • Weight loss FDA Drug Safety Communication: Update to ongoing safety review of Actos (pioglitazone) and increased risk of bladder cancer, FDA, June 15, 2011 The use
of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case - control study, British Medical Journal, May 31, 2012
Actos» label also notes that the use
of pioglitazone for more than one year may be associated with an increased risk of bladder cancer.
Not exact matches
All
of them had been treated with either Avandia or Actos, (
pioglitazone), a very similar drug.
A pooled analysis
of data from two randomised trials comparing vitamin E versus placebo, and the placebo group from another trial comparing vitamin E use versus non-use, demonstrates that the efficacy
of vitamin E is comparable to other treatments for NASH, including
pioglitazone, metformin and obeticholic acid.
Pills to control blood sugar in people who have diabetes — like Avandia (rosiglitazone) or Actos (
pioglitazone)-- make it harder to get sodium out
of the body, which leads to swelling.
Effect
of Montmorency tart cherry versus PPAR agonist
pioglitazone on stroke - related phenotypes and inflammation.
Both the Winn Feline Foundation and the Morris Animal Foundation currently fund studies in Illinois to see if the human anti-diabetic drug,
pioglitazone, might help control (or perhaps, even prevent) the progression
of diabetes in cats as it apparently does in humans (ref).
This generic will come with the same warnings as Actos, including one stressing that
pioglitazone may cause or exacerbate heart failure or up the risk
of bladder cancer.
Our drug injury attorneys work to protect the rights
of patients harmed by dangerous drugs like Actos (
pioglitazone), a Type 2 diabetes medication that poses serious health risks.
In Re: ACTOS (
Pioglitazone) Products Liability Litigation, MDL No. 2299 (United States District Court, Western District
of Louisiana):
He currently serves as co-lead counsel in the In re: Gadolinium Based Contrast Agent Litigation, which is pending in the U.S. District Court for the Northern District
of Ohio; the Plaintiff's Executive Committee in the In re: Abilify Products Liability Litigation pending in the U.S. District Court for the Northern District
of Florida; the Plaintiff's Executive Committee in the In re: Benicar Products Liability Litigation pending in the U.S. District Court for the District
of New Jersey; the Plaintiff's Steering Committee in the In re: Actos (
Pioglitazone) Products Liability Litigation pending in the U.S. District Court for the Western District
of Louisiana; and the Plaintiff's Steering Committee in the In re: Fresenius Granuflo / Naturalyte Dialysate Products Liability Litigation pending in the U.S. District Court for the District
of Massachusetts.
According to an article that appeared Consumer Reports on August 21, 2012, the FDA advises against using the generic form,
Pioglitazone, or the brand name Actos because
of the risks discussed in this blog.
Actos is still sold in the US even though last year the US Food and Drug Administration put out a safety warning that
pioglitazone - Actos is the brand version - may increase the chances
of bladder cancer when taken for more than a year.
The FDA is now recommending that drugs with
pioglitazone not be prescribed to people who already have blood cancer and that those with a history
of the disease must be cautious should they choose to take this medication.
The FDA especially wants people already suffering from blood cancer or who have a history
of the disease to be very careful when taking Actos, or better yet refrain from taking medications with
pioglitazone, which is the generic name
of Actos.