Sentences with phrase «of placebo treatment»

The study put people on 3 months of placebo treatment and 3 months of active treatment with hydrocortisone and fludrocortisone.
If so, such people would not only benefit from all kinds of placebo treatment, they also could be excluded from clinical drug trials.

Not exact matches

In a 564 - person trial, patients whose ovarian cancer recurred (and who had already started treatment with chemotherapy) given Rubraca, part of a new class of cancer drugs called «PARP» inhibitors, lived, on median, for double the amount of time without their disease getting even worse compared with those given a placebo.
In a late - stage study, Aimmune, a biotech immunotherapy allergy treatment taken via pill, found that of the roughly 500 kids with peanut allergies between the ages of 4 - 17 who were part of the trial, 67 % of those who received the treatment were able to tolerate 600 milligrams of peanut protein (about two to four peanuts) after about a year of treatment, while only 4 % of those who got the placebo could tolerate that dose of peanut protein.
Patisiran was being evaluated in a late - stage study against a placebo for the treatment of patients with hereditary ATTR (hATTR) amyloidosis with polyneuropathy.
He contributes to other large - scale clinical trials including SAVE (evaluating whether treatment of obstructive sleep apnoea with continuous positive airways pressure can reduce the incidence of serious CV events in patients with established CVD), and CREDENCE, a randomised, double - blind, placebo - controlled trial assessing whether canagliflozin can slow the progression of diabetic nephropathy in patients with type 2 diabetes.
Of them all, giving your baby a probiotic is perhaps the one treatment that just might help, although a very recent double - blind, placebo - controlled randomized trial in Australia concluded that «L reuteri DSM 17938 did not benefit a community sample of breastfed infants and formula fed infants with colic.&raquOf them all, giving your baby a probiotic is perhaps the one treatment that just might help, although a very recent double - blind, placebo - controlled randomized trial in Australia concluded that «L reuteri DSM 17938 did not benefit a community sample of breastfed infants and formula fed infants with colic.&raquof breastfed infants and formula fed infants with colic.»
Unfortunately, these types of treatments don't usually help or only help by way of a placebo effect and they can have side effects.
Additionally, a systematic review of PPI studies in treatment of reflux determines that they provide no more benefit than placebos.7
In a second study of 18 children with peanut allergies, the researchers gave the peanut protein treatment to 12 children and placebo powder to the other six.
«I'm on the record as saying I absolutely do not believe in the explanations for homeopathy and how it quote unquote works,» she says, before adding: «But I do believe in the placebo effect and it's possible that if a placebo is the best treatment for a lower back pain, for example, then that's what the evidence shows and in a lot of these areas there hasn't been enough research done to really tell that.
Treatment with zoledronic acid was associated with a 73 percent and a 65 percent reduction in bone loss relative to placebo at 12 weeks and 24 weeks respectively, an effect that lasted throughout the 48 weeks of the study.
With two additional years of denusomab treatment, their bone mineral density increased further and the wrist fracture rate declined to levels significantly lower than the FREEDOM placebo rate (rate ratio = 0.57, 95 % CI = 0.34 - 0.95; p = 0.03).
Hep C patients being treated for opioid addiction achieved high rates of sustained virologic response after 12 weeks of therapy with elbasvir - grazoprevir compared to those taking placebo for 12 weeks before beginning the drug treatment.
The three - armed trial evaluated the efficacy of chiropractic spinal manipulative therapy (CSMT) in the treatment of migraine versus placebo (sham chiropractic) and control (usual drug treatment).
Patients were randomised into eight treatment groups: a single dose regimen of 200, 300 or 500 mg inclisiran, or placebo; or a two dose regimen of 100, 200 or 300 mg inclisiran, or placebo, at days one and 90.
«A significant body of research has resulted in a shift from thinking of placebos as just «dummy» treatments to recognizing that placebo effects encompass numerous aspects of the health care experience and are central to medicine and patient care,» said the article's coauthor Ted Kaptchuk, Director of the Program in Placebo Studies at Beth Israel Deaconess Medical Center (BIDMC) and Professor of Medicine at Harvard Medical placebo effects encompass numerous aspects of the health care experience and are central to medicine and patient care,» said the article's coauthor Ted Kaptchuk, Director of the Program in Placebo Studies at Beth Israel Deaconess Medical Center (BIDMC) and Professor of Medicine at Harvard Medical Placebo Studies at Beth Israel Deaconess Medical Center (BIDMC) and Professor of Medicine at Harvard Medical School.
Placebos are used to help accurately measure clinical responses / outcomes when studying the effects of medications, therapies, and other treatments.
In the four weeks after the first treatments, people had about 15 percent fewer days of headache compared with a placebo or dummy injection.
Participants were then randomized to receive one of four placebo - based treatments: vasopressin, oxytocin, saline, or no treatment.
Researchers conclude that for the treatment of primary insomnia, neurofeedback does not have a specific efficacy beyond unspecific placebo effects.
The order of trainings, that is, real or placebo neurofeedback treatment was counterbalanced across subjects and the twelve sessions were completed within 4 weeks.
Researchers from the University of Florida investigated whether lessening of pain sensitivity attributed to SMT is specific to the procedure itself or occurs as a placebo effect from treatment expectation.
Alternatively, the Institute investigated the benefit and harm of treatment of ASB detected by screening compared with non-treatment or placebo.
After four weeks of hospital treatment, the subjects taking the drug reported fewer spontaneous and stress - induced alcohol cravings than patients given a placebo did.
What doctors need, she says, is a list of indicators of diseases for which placebo treatments might be suited.
While 35 per cent of the patients who had not received any treatment reported an improvement, 59 per cent of the placebo group felt better.
For 24 weeks, 1,583 participants in the aptly named GAIT (Glucosamine / chondroitin Arthritis Intervention Trial) were given one of the following treatments: glucosamine, chondroitin sulfate, both in combination, a placebo, or the COX - 2 inhibitor Celebrex (celecoxib) as a control.
«Our results show that the number of responders was three times higher when correct information was given than when patients thought they were treated with an ineffective active placebo, even though the pharmacological treatment was identical,» says author Vanda Faria.
For those in the treatment group, the number of seizures per month was cut roughly in half, on average, compared to a negligible decline in the placebo group, researchers reported this week in The New England Journal of Medicine.
The study was not powered to demonstrate a treatment effect on kidney function, but there was no evidence of a benefit associated with bosutinib compared with placebo over the 2 - year treatment period.
The results imply a marked placebo component, related to expectancies, in SSRI treatment, underscoring the importance of the communication between prescriber and patient.
In a related Editor's Note, Deborah Grady, M.D., M.P.H., a deputy editor of JAMA Internal Medicine, writes: «It is possible that treatment beyond one year would result in better outcomes, but these data provide no support for use of higher - dose cholecalciferol replacement therapy or indeed any dose of cholecalciferol compared with placebo
Nearly half of the studies (eight of the acute and one of the chronic pain) suggested that antidepressants resulted in significant treatment benefits over placebo.
TRINOVA - 2 is evaluating pegylated liposomal doxorubicin in combination with either placebo or trebananib in previously treated patients with ovarian cancer while TRINOVA - 3, also known as ENGOT - Ov2 and Gynecologic Oncology Group — 3001, is studying the use of trebananib in front - line treatment adding it to carboplatin / paclitaxel.
Dr Jones, said: «This new meta - analysis shows that baclofen is no more effective than placebo on a range of key outcome measures, suggesting that the current increasing use of baclofen as a treatment for alcohol use disorders is premature.»
Within one hour of the anticipated start of anesthesia, 64 people received the combination treatment of Zofran (the standard therapy) plus aprepitant; the remaining 60 patients got the Zofran and a placebo.
The overall risk of nausea and vomiting within 24 hours was about 60 percent lower with gabapentin, compared to inactive placebo (or other treatments).
While the treatment did have some favorable effects, in the main measure of outcome — measured with a cognitive test called the Alzheimer's Disease Assessment Scale - cognitive subscale — the researchers did not observe any statistically significant benefit compared with placebo.
Furthermore, the report accuses the British Homeopathic Association (BHA), which had submitted evidence to the panel, of cherry - picking, and even, in one case actively misrepresenting, research into the treatment (a famous study that concluded its findings were «compatible with the notion that the clinical effects of homeopathy are placebo effects» was cited by the BHA as evidence of the treatment's efficacy.)
Now a group of physicians have designed the fecal treatment's first double - blind trial, in which neither patient nor researcher knows whether a placebo or a healthy microbiome is being delivered to the ailing gut.
The result: although the sex lives and sexual satisfaction of the women receiving oxytocin treatment improved significantly, the group that only received a placebo also had significantly improved scores.
Using a sample of 10 resistance - trained men in their early 20s, protein supplementation consisted of 3 treatment groups: whey protein isolate, soy protein isolate, or a maltrodextrin placebo control.
At the end of treatment, the women who received the drug reported a 21 - point reduction on a standard scale of depression symptoms, compared with about 9 points for the women on a placebo.
Over six months of treatment, there was a 27.6 per cent reduction of becoming full blown MS. (The risk was 61 per cent in the placebo group and 33.4 percent in the minocycline group.)
In fact, if the placebo / expectation component of a treatment is eliminated by means of a hidden administration (unbeknownst to the patient), the psychological component of the therapy is absent as well.
To explain why antidepressants in such trials nevertheless often cause greater symptom relief than placebo, it has been suggested that SSRI - induced side effects will make the patient understand that he or she has not been given placebo, hence enhancing his or her belief of having been given an effective treatment.
However, to have the statistical power to confirm trends even in these populations would probably take at least 100 people in both the treatment and placebo arms of the trial.
However, if SSRIs had indeed acted merely by means of a placebo effect, these drugs should not outperform actual placebo in clinical trials where patients have been treated with an SSRI or with ineffective placebo pills, and where neither the physician nor the patient knows which treatment the patient has been given until the study is over.
Patients taking part in the study will receive either Genistein Aglycone or placebo (an inactive substance that looks like the treatment) with food, over a period of 12 months.
a b c d e f g h i j k l m n o p q r s t u v w x y z