The incidence
of placental abnormalities, such as placenta previa, in future pregnancies increases with each subsequent cesarean delivery, from 1 % with one prior cesarean delivery to almost 3 % with three or more prior cesarean deliveries.
Not exact matches
Some
of these causes might be chromosomal
abnormalities, cervical insufficiency, congenital birth defects,
placental problems, or other factors.
Causes
of pregnancy loss include antepartum conditions,
placental conditions, infection, growth restriction, hormonal problems, chromosomal
abnormalities, and immune system responses.
It underscores the importance
of folate not only in reducing the incidence
of early embryonic defects, but also in the prevention
of developmental delays and
placental abnormalities that may increase susceptibility to other defects and to reproductive complications.
Placenta praevias, IUGRs, high order multiples, cervical incompetence,
placental insufficiency, cholestasis
of pregancy, breech, Pre-eclamptics, eclamptics, women with pre-existing serious medical conditions, grand multiparas, women with BMI over 40, extreme prematurity, foetal
abnormalities...
Of the remainder, many are linked to
placental abnormalities but it is often unclear why the
abnormalities occur.
Endothelium - specific ablation
of PDGFB leads to pericyte loss and glomerular, cardiac and
placental abnormalities.
In embryos where the mix
of normal and abnormal cells was half and half, the researchers observed that the abnormal cells within the embryo were killed off by «apoptosis», or programmed - cell death, even when
placental cells retained
abnormalities.