Being overweight or obese has been known to increase the risk of multiple myeloma, a
cancer of the plasma cells in the blood and bone marrow that develops more often after age 60.
In this type
of plasma cell neoplasm, the abnormal plasma cells (myeloma cells) are in one place and form one tumor, called a plasmacytoma.
Multiple myeloma is a cancer
of plasma cells in the blood that causes tumor growths in bone marrow.
The new findings build on prior research from the Dhodapkar lab demonstrating that patients with Gaucher disease, an inherited lipid storage disorder, have a significant increased risk for developing myeloma; and the discovery of a subset of lipid - reactive immune cells, called type II NKT - TFH, that promote the
development of plasma cells.
Multiple myeloma is a cancer involving the
growth of plasma cells, which are immune cells that make antibodies to fight infection.
In this specific study, among other studies the group has published in this area, mice with multiple myeloma — a malignant
disease of the plasma cells produced in bone marrow and spread throughout the body via the circulatory system — were treated with the selective anti-cancer drug Velcade (bortezomib).
It is required for progenitor cell development or helps B - cells differentiate and proliferate, and promotes the
formation of plasma cells from B - cells.
You can also register for our webinar on genomic
analysis of plasma cell - free DNA, which is coming up on April 10 and features Dr. Geoffrey R. Oxnard.
Early Onset, EBV - PTLD in Pediatric Liver - Small Bowel Transplantation Recipients: A
Spectrum of Plasma Cell Neoplasms with Favorable Prognosis.
Gut - associated lymphoid tissue (GALT) is the prominent part of mucosal - associated lymphoid tissue (MALT) and represents almost 70 % of the entire immune system; moreover, about 80 % of plasma cells [mainly immunoglobulin A (IgA)- bearing cells] reside there.
When tissue from the affected footpads is examined by pathologists, the most remarkable finding is the presence of abnormally high
numbers of plasma cells.
We are starting 2013 with Gambler, a 9 year old neutered male Australian Cattle dog, who was presented to our Oncology department at VRCC in early April 2011, with a biopsy confirmed
diagnosis of an plasma cell tumor of the right lower jaw.
In this
type of plasma cell neoplasm, less than 10 % of the bone marrow is made up of abnormal plasma cells and there is no cancer.
Obesity increases the risk of myeloma, a cancer
of plasma cells that accumulate inside the bones.
The laboratory primarily studies multiple myeloma, a cancer
of plasma cells.
Cancers of the breast, prostate, colorectal system, liver and kidney as well as multiple myeloma, a cancer
of the plasma cells that make antibodies to fight viruses and bacteria, strike earlier, deadlier and more often in some racial and ethnic groups, the National Cancer Institute has shown.
The research describes how a combination of glucose uptake and mitochondrial pyruvate import allow a specific type
of plasma cell to sustain durable antibody production.