Sentences with phrase «of plasma proteins»

During illness, the body of the tongue will change according to the strength or weakness of the arterial or venous blood flow, lymphatic drainage and concentration of plasma proteins.

The results show that the CM - associated response in mice that developed neurological signs comprise mainly acute - phase reaction and coagulation cascade activation, and indicate the leakage of plasma proteins into the brain parenchyma.

«Smoking, COPD, and 3 - Nitrotyrosine Levels of Plasma Proteins.»

Concentrations of plasma proteins were between 5 and 20 times higher than levels found at 4 o'clock in the afternoon.

Not exact matches

In 2000, the company entered into a joint venture with the American Red Cross that aimed to use ProMetic's technology to pull therapeutic proteins out of blood plasma.

Sled dogs fed a diet consisting of 35 % of energy from protein had higher plasma volume than dogs fed a diet with 18 % of energy from protein (63).

The effects of fat and protein on glycemic responses in nondiabetic humans vary with waist circumference, fasting plasma insulin, and dietary fiber intake

Effect of Intake of Different Dietary Protein Sources on Plasma Amino Acid Profiles at Rest and After Exercise.

** The immunological defense system of the soft mucosa, which may produce antibacterial and antiviral proteins such as lysozyme, also found in mothers milk, and plasma cells, which secrete immunoglobulin antibodies.

When logistic models were stratified by the presence or absence of hypertensive disease, only maternal age older than 34 years (odds ratio [OR], 1.4; 95 % confidence interval [CI], 1.0 - 2.0), pregnancy - associated plasma protein - A of the 95th percentile or less (OR, 1.9; 95 % CI, 1.2 - 3.1), and alpha fetoprotein of the 95th percentile or greater (OR, 2.3; 95 % CI, 1.4 - 3.8) remained statistically significantly associated for abruption.In this large, population - based cohort study, abnormal maternal aneuploidy serum analyte levels were associated with placental abruption, regardless of the presence of hypertensive disease.

Because blood is a complex suspension of red and white blood cells and platelets suspended within a plasma that contains various proteins, it can exhibit complex flow behavior.

The test measures blood plasma levels of a sticky protein called amyloid - beta.

The SCARB1 mutation affects 43 percent of the population, and within this group the carriers for the rs10846744 variant have a 45 percent increased risk of heart attack — likely due to low LAG3 protein in their plasma.

Larger biomarker signatures can be detected with technology from CDI Laboratories, which offers microarrays of functional human proteins (over 20,000 on a single array) to test the antibodies present in human liquid biopsy samples, such as blood, serum, plasma, CSF, or tissue lysates.

The test, which could be available to patients within two years, identifies the chemical signatures found in the plasma of blood joint proteins damaged by oxidation, nitration and glycation; the modification of proteins with oxygen, nitrogen and sugar molecules.

Wnt proteins, regulators of development in many organisms, bind to seven transmembrane — spanning (7TMS) receptors called frizzleds, thereby recruiting the cytoplasmic molecule dishevelled (Dvl) to the plasma membrane.Frizzled - mediated endocytosis of Wg (a Drosophila Wnt protein) and lysosomal degradation may regulate the formation of morphogen gradients.

«Starting with our cell model that mimics human pancreatic cancer progression, we identified released proteins, then tested and validated a subset of these proteins as potential plasma biomarkers of this cancer,» Zaret said.

In multiple myeloma, normal plasma cells transform into malignant myeloma cells and produce large quantities of toxic abnormal immunoglobulin called monoclonal protein that can damage multiple organs.

Multiple myeloma is preceded by a blood disorder called monoclonal gammopathy of undetermined significance (MGUS) in which abnormal plasma cells produce many copies of an antibody protein.

Wyss - Coray, whose group did most of the mouse studies that inspired the clinical trial, now plans to conduct a second, larger trial using plasma from which many proteins and other molecules have been removed.

They found levels of numerous proteins differed according to the plasma source age.

They also gave old mice infusions of young blood plasma (the liquid component of blood containing proteins and hormones but no cells), which significantly improved their performance in learning and memory tests.

This one - way adsober, which has been specifically developed for treating IgE - related diseases, reduces the plasma IgE level by running the patient's blood through a «column» that traps the IgE antibodies — by means of Sepharose beads carrying IgE - binding proteins.

They then injected the protein into elderly mice with normal immune systems, and found this reproduced the beneficial effects of cord plasma on both memory performance and LTP in the hippocampus whereas mice engineered to lack TIMP2 showed reduced LTP.

Then there's the West Palm Beach symposium, held to recruit participants for a study testing what happens when aging people get infusions of plasma (the fluid part of blood packed with signaling proteins and other molecules but no red or white cells) from young people who've taken a drug meant to activate their immune system.

Results showed that d - ribose supplementation didn't promote the formation of glycated plasma proteins or any other adverse effects, and actually protected the horses from cramping while enhancing muscle recovery.

When the colds reached their peak, Persson's team tested the volunteers» noses for plasma proteins, a key sign of inflammation.

The horses were run through a series of low and high intensity workouts, and were subject to a series of blood tests that measured glycated plasma proteins, the advanced glycation end product of interest.

By examining blood plasma of two - year - olds exposed to the disease, researchers have discovered a new vaccine target: a protein recognized by the immune systems of malaria - resistant children.

Instead, inflammation causes the mucous cells of the nose to release their own liquid, although the concentrated plasma proteins could attract liquid by osmosis as they seep towards the nasal cavity, he says.

Plasma is given routinely to patients, so trials of this approach, unlike those testing a new protein, would not require U.S. Food and Drug Administration approval, Wyss - Coray says.

The Brain Trauma Indicator measures blood plasma levels of the UCH - L1, a protein scientists believe helps dispose of cellular waste in the brain, and GFAP, a structural protein found in non-neuronal cells called astrocytes.

Indiana University School of Medicine researchers have identified a small protein with a big role in lowering plasma glucose and increasing insulin sensitivity.

It plays a major role in metabolism and has a number of functions in the body including drug detoxification, glycogen storage, and plasma protein synthesis.

• Explore the use of covariate modeling to establish personally normalized plasma protein profiles (PNPPP) to reduce non-disease-related variation and maximize clinical potential

When levels of proteins in the plasma fall, the capillaries no longer effectively «hold» water, so fluid steadily leaks into surrounding tissues.

A cell membrane, plasma membrane or plasmalemma is a selectively permeable lipid bilayer coated by proteins which comprises the outer layer of a cell.

It has been found that the establishment and maintenance of polarity is governed by the interdependent relationship between the polarity marker protein on the plasma membrane (cell membrane), actin, the microtubule cytoskeleton, and membrane vesicle transport.

«A higher plasma concentration of these proteins means that there has been greater damage of muscle fibres and, therefore, a greater probability of fatigue.

The type of B cells that the scientists tapped for the coveted proteins are known as antibody - secreting plasma cells (ASCs).

Before the fusion of synaptic vesicles with the plasma membrane, a protein complex is thought to form between VAMP — an integral membrane protein of the vesicle — and two proteins associated with the plasma membrane, SNAP - 25 and syntaxin.

They exposed plasma from the samples to purified proteins of avian influenza virus H3, H4, H5, H6, H7, H8 and H12 subtypes using two laboratory tests to see how many different viruses participants reacted to, and how strongly.

Given their high rates of protein synthesis, antibody - producing plasma cells display particularly high levels of metabolic activity.

Thus, distribution and mobility of specific lipid species at the plasma membrane appears to precisely regulated by membrane - associated proteins.

The team found that cord plasma has elevated levels of a protein called TIMP2.

Because certain cell secretion pathways have been suggested to be required for this process, University of Buenos Aires researcher Matías Ostrowski and colleagues investigated whether a role might be played by Rab27a, a protein that guides delivery of membrane - bound compartments called endosomes to the plasma membrane.

Once inside a neuron, botulinum toxin cleaves proteins responsible for fusion of chemical containers, known as vesicles, with the plasma membrane.

New HIV - 1 particles assemble at specialized sites in the plasma membrane that are enriched in PIP2, a phospholipid component of the membrane that recruits a viral protein called Pr55Gag (Gag) that directs HIV - 1 assembly.

On the basis of a cursory inspection of Takebe's data presented at the meeting, Grompe says that the liver bud was producing only a small fraction of the albumin — a plasma protein that is a key marker of liver function — that it should.

The scientists observed that these proteins move extremely slowly in the plasma membrane of the yeast and discovered how they travel through the membrane to reach the islands.