Sentences with phrase «of programmed cell death»

They are heavily involved in cellular metabolism as well as in apoptosis, the process of programmed cell death by which potentially cancerous cells can be killed before they multiply and spread.

Cells that detach from their environment undergo a form of programmed cell death called anoikis.

When researchers knocked out both Atm and Tdp1, Top1cc accumulation rose substantially as did a form of programmed cell death called apoptosis.

After graduating, he went to the University of California, Davis, and settled on investigating the genetic regulation of programmed cell death in plants.

CED - 4 translocation induced by the cell - death activator EGL - 1 was blocked by a gain - of - function mutation in ced - 9 but was not dependent onced - 3 function, suggesting that CED - 4 translocation precedes caspase activation and the execution phase of programmed cell death.

New research shows that microRNA - 486 is a potent tumor - suppressor molecule in lung cancer, and that the it helps regulate the proliferation and migration of lung - cancer cells, and the induction of programmed cell death, or apoptosis, in those cells.

Kaelin's group reasoned that if they could disable this remaining safety check in cancer cells, then E2F would become abundant enough to provoke a spiral of programmed cell death.

Nivolumab is an inhibitor of the programmed cell death protein 1 (known as PD - 1), which functions as an immune checkpoint, playing an important role in the immune system.

Apoptosis and necrosis were quantified using immunofluorescence assays; bioconjugate - treated cells were early apoptotic after 4 hours, proving effective initiation of programmed cell death.

During that year, and subsequent years spent as a postdoc in Morata's lab (and later with Konrad Basler at the University of Zurich, Switzerland), Moreno was able to link the previously isolated phenomenon of cell competition to the well - established process of programmed cell death.

There, in a quest to develop targeted therapies for ovarian cancer, she began studying necroptosis, a form of programmed cell death.

The process of programmed cell death, or apoptosis, is one such mechanism.

Apoptosis is the process of programmed cell death.