Dr. Summer and colleagues are currently working to develop a therapy that could restore lipid production in the lungs
of pulmonary fibrosis patients and slow the fibrotic process.
And an earlier study
of pulmonary fibrosis patients who took everolimus found that among 11 patients who had lung transplants, there was no increased incidence of wound - healing / anastomosis problems.
Not exact matches
To make these cracks, the researchers turned to Pseudomonas aeruginosa — a bacterial species that often builds biofilms within the lungs
of cystic
fibrosis patients, which can lead to chronic obstructive
pulmonary disease and subsequently death.
«
Pulmonary fibrosis slowly robs
patients of breath and finally life,» said Paul W. Noble, MD, professor and chair
of the Department
of Medicine and director
of the Women's Guild Lung Institute at Cedars - Sinai.
Compared with lung tissue
of disease - free individuals, lung tissue from
patients with
pulmonary fibrosis had far fewer AEC2 cells, and those that remained were less able to renew themselves.
Experts agree the treatment is transformative for
patients with the Cheevers» form
of CF. «We have just started using it in practice,» says Henry Dorkin, a pediatric
pulmonary specialist and director
of the Cystic
Fibrosis Center at Children's Hospital in Boston.
As a physician who treats
patients with
pulmonary fibrosis in a multidisciplinary clinic at Jefferson, the research has a sense
of urgency.
Pulmonary fibrosis, an ongoing process
of scarring that leaves
patients chronically short
of breath, can progress in severity until the only course
of treatment is lung transplant.
«This probably only explains a small subset
of patients with
pulmonary fibrosis,» he says.
Palmer said the multi-site registry will help doctors who treat
patients with idiopathic
pulmonary fibrosis better understand how to diagnose and manage the disease, while it will also help researchers uncover the basic causes and mechanisms
of the disease.
April 17, 2013 Gene study helps understand
pulmonary fibrosis A new study looking at the genomes
of more than 1,500
patients with idiopathic
pulmonary fibrosis, a rare and devastating lung disease, found multiple genetic associations with the disease, including one gene variant that was linked to an increase in the risk
of death.
Personalised medicine is becoming relevant in the treatment
of lung cancer [42, 43] and may have relevance for other lung diseases, like
pulmonary fibrosis, asthma and
pulmonary hypertension, but disease - related basic research aimed at searching for biomarkers is needed to achieve personalised and
patient - specific treatments for lung diseases.
In the long run, the scientists hope their lung stem cell therapy will also help
patients with other lung
fibrosis conditions
of which there are dozens, including COPD, cystic
fibrosis, and fibro - cavernous
pulmonary tuberculosis.
The biggest thing is making sure you can qualify for life insurance with SBLI, so lets cover (in general) what SBLI will and won't insure: SBLI Underwriting Uninsurable medical scenarios with SBLI: • Aids / HIV + status • ALS (Amyotrophic Lateral Sclerosis) • Alzheimer's disease or dementia or significant cognitive impairments related to functionality • Cancer diagnosis within last 2 years • Chronic pain treatment, severe, receiving disability, narcotic use • Cirrhosis
of the Liver • Congestive heart Failure • COPD / Emphysema or chronic bronchitis - Severe or with current nicotine use • Cystic
Fibrosis • Defibrillator use • Depression, severe, recurrent or with multiple in -
patient hospitalization history • Diabetes with co-morbidities that include significant cardiac disease, or impairment
of renal function or mobility • Heart / Cardiac Disease - multiple vessels diagnosed within 2 years or any past history with current nicotine use • Muscular Dystrophy • Multiple Sclerosis, if symptoms progressing • Organ Transplants, in most scenarios • Quadriplegia •
Pulmonary hypertension • Renal failure, Renal insufficiency - severe • Stroke within 1 year • Suicide attempt within 5 years • Surgical repair
of heart valves, aneurysms, intracranial tumors, major organs within six months, including gastric bypass Uninsurable non-medical scenarios: • Marijuana use, 4 or more times weekly • Substance abuse / misuse within last 5 years • Criminal activity - any history within the last 10 years • DUI, more than 2 or under age 25 if within 1 year • Unemployed (other than homemakers or retired) with minimal household income or dependent on SSI / disability benefits • Bankruptcy filing within 2 years • Liens / Judgements - outstanding activity that exceeds $ 50K