Sentences with phrase «of risk of an adverse reaction»

Experts in veterinary medicine have been calling for a decrease of live and inactivated vaccination of companion animals because of the risk of adverse reaction to vaccines.

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

When combined with rice flour or tapioca flour, however, quinoa - based products definitely qualify as gluten - free and should help reduce risk of adverse reactions.

Both of these factors would be expected to decrease the risk of an adverse reaction to quinoa — especially in comparison to a cereal grass like wheat.

If you are concerned about the risk of your baby being allergic to a food, be sure to watch out for any adverse reactions, such as a rash or hives.

The softness of the pillow comes in part from its high - quality, 100 % organic cotton fabric; additionally, a hypoallergenic polyester filling decreases the risk that sensitive babies will have an adverse skin reaction to the pillow.

Because the risks of serious adverse reactions often outweigh the benefits, over-the-counter medicines must be used with caution in babies and young children.

Taking antibiotics when they are not needed creates additional health risks as it increases the chance a patient will experience an adverse drug reaction, and also leads to the development of antibiotic - resistant bacteria which affects everyone in the community.

A thorough comparison of adverse food reactions in humans and animals offers insight into the risk factors for the development of the condition, and can thus lead to improved recommendations for the prevention and treatment of adverse food reactions in animals and humans.

The long - term challenge for research - ers, Halpern says, is to determine which settings can exploit the therapeutic potential of hallucinogens while reducing the risk of adverse reactions.

The increased risk closely correlates with the frequency of a gene variant previously associated with that adverse reaction, supporting recommendations to screen for that variant in patients from those populations.

«We found that Asian and black patients have a substantially higher risk of severe cutaneous adverse reactions to urate - lowering drugs than do white or Hispanic patients, which correlates with the frequency of the HLA - B * 5801 gene in their U.S. populations,» says Hyon K. Choi, MD, DrPH, of the MGH Division of Rheumatology, Allergy and Immunology, senior author of the report that has been published online in Seminars in Arthritis and Rheumatism.

The reviewers identified several risk factors for women in the U.S. that were predictive of adverse reactions subsequent to abortion, including perceptions of stigma, a need for secrecy, low social support and personality traits such as coping style.

«Blood metal ion levels can identify hip replacement patients at low risk of ARMD: Blood metal ion levels can effectively identify patients at low risk of adverse reactions after metal on metal hip replacement.»

On April 7 reports of adverse skin reactions and heart problems prompted the FDA to ask Pfizer to withdraw Bextra, another COX - 2 inhibitor, and to include a warning about the health risks for Celebrex.

Patients with «metal on metal» (MoM) artificial hips are at risk of complications caused by adverse reactions to metal debris (ARMD).

A simple lab - based skin test which eliminates the risk of adverse reactions to new drugs, cosmetics and household chemicals has been developed by a Newcastle University team.

None of the patients experienced adverse reactions to the iron nanoparticles, though the FDA has previously noted a small risk of allergic reaction to the nanoparticles» coating.

Researchers and doctors at Uppsala University, along with Swedish and international collaboration partners, have found gene variants that predict the risk of a serious adverse reaction to drugs used for the treatment of hyperthyroidism.

«Genetic test shows patients at risk of a serious adverse reaction to toxic goitre treatment.»

An intervention would be ethically justified if the likelihood of an effective immune response significantly outweighs the risk and severity of adverse reactions to the intervention.

An international research team led by Mia Wadelius, Uppsala University / SciLifeLab, have found gene variants that predict the risk of a serious adverse reaction to drugs used for the treatment of hyperthyroidism.

This suggests that such groups are at greater risk of abusing alprazolam and may experience more severe adverse reactions if they do.

While prostate changes can occur with testosterone replacement, a study published in The Journal of Clinical Endocrinology & Metabolism in June of 2010, which looked closely at the adverse reactions reported in 51 other studies, found there to be no increased risk of the development of prostate cancer, prostate related urinary symptoms, or elevated PSA (prostate specific antigen).

Thats a pretty damning statistic, making the relative risks for adverse reactions among ephedra users 10 - to 40-fold greater than the risk among users of other herbal products.

This will reduce your risk of adverse reactions due to underlying health problems such as low blood pressure (hypotension).

A final area of likely benefit involves decreased risk of allergy — especially for individuals who have adverse reactions to certain grains and seek practical alternatives.

Both of these factors would be expected to decrease the risk of an adverse reaction to quinoa — especially in comparison to a cereal grass like wheat.

Other risks of vaccines are mainly mild adverse reactions such as mild fever, dimished appetite, discomfort at vaccination site, or more serious, an allergic reaction.

The amount of blood volume needed to be taken from a cat and their small size in combination with using a sedative may increase the risk of an adverse reaction such as low blood pressure.

Although an injectable inoculation is also available, the nasal version provides protection more quickly and there's no risk of an adverse reaction at the injection site.

The test results are useful in minimizing the risk of adverse reactions and in assessing the patient's infection status.

• increases the risk of cardiac hemangiosarcoma by a factor of 1.6 • triples the risk of hypothyroidism • increases the risk of progressive geriatric cognitive impairment • triples the risk of obesity, a common health problem in dogs with many associated health problems • quadruples the small risk (< 0.6 %) of prostate cancer • doubles the small risk (5; this is a common cancer and major cause of death in some breeds • triples the risk of hypothyroidism • increases the risk of obesity by a factor of 1.6 - 2, a common health problem in dogs with many associated health problems • causes urinary «spay incontinence» in 4 - 20 % of female dogs • increases the risk of persistent or recurring urinary tract infections by a factor of 3 - 4 • increases the risk of recessed vulva, vaginal dermatitis, and vaginitis, especially for female dogs spayed before puberty • doubles the small risk (< 1 %) of urinary tract tumors • increases the risk of orthopedic disorders • increases the risk of adverse reactions to vaccinations One thing is clear — much of the spay / neuter information that is available to the public is unbalanced and contains claims that are exaggerated or unsupported by evidence.

Cats metabolize some NSAIDs drugs more slowly than dogs, potentially increasing the risk of adverse drug reactions.

As with any medication, there is some risk of adverse reaction to flea and tick treatment.

In older animals, chest radiographs and electrocardiogram (ECG) are often recommended to ensure there is no pre-existing pathology in the heart or lungs that might increase the risk of an adverse reaction.

Owners may reduce the risk of adverse gastrointestinal reactions by giving chondroitin with food.

Because vaccinating an animal which is already immune to a disease does not increase their immunity but does in fact raise the risk of adverse reactions, it is important to avoid over-vaccination.

Therefore, we should advise companion animal breeders and caregivers of the potential for genetically susceptible littermates and relatives to be at increased risk for similar adverse vaccine reactions (Dodds, 1997, 1999, 2001).

Long Island City Veterinary Center believes that a well - balanced vaccination protocol is the best means to protect your pet from disease as well as the risk of an adverse reaction to a vaccine.

Dr. Schultz knows there's no benefit in over-vaccinating animals because immunity is not enhanced, but the risk of harmful adverse reactions is increased.

Given that the risk of an adverse reaction, a reasonable client would not elect Vaccination of their pet if provided with the above information.

Addition of an unnecessary antigen to the vaccination protocol will result in a lesser immunity to the important diseases like parvovirus and distemper, and increase the risk of adverse reactions.

Because of its lack of efficacy and the very great risk of adverse reactions, Leptospirosis vaccination is not the answer.

The client is paying for something with insignificant or no effect, except that the patient is being exposed to unnecessary risk of an adverse reaction.

Melissa Kennedy, DVM, PhD, DACVIM wrote in DVM360 on - line magazine: «The likelihood of adverse reactions in dogs has been found to correlate with the size of the dog and the number of inoculations given, with higher risk associated with small size and multiple inoculations.»

While experts might be refusing to use them on their own dogs because the risk of infection isn't that high, it's more likely due to the great number and significance of adverse reactions.

Certain small dog breeds are slightly more at risk of having an adverse reaction to vaccination than larger dogs, but no breed / size / individual is immune to the risks involved.

«Administration of multiple doses of parenteral vaccine at the same appointment, particularly among small breed dogs (< 10 kg), may increase the risk of an acute - onset adverse reaction.

Dr. Dodds feels the holistic veterinary community needs to document more case studies of adverse reactions and do cohort reports so that DVMs have access to information about predisposing factors that increase vaccine risks for certain pets.